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PDZ Domain Containing 3 Proteins (PDZD3)

Guanylyl cyclase C (GCC, or GUCY2C\; MIM 601330) produces cGMP following the binding of either endogenous ligands or heat-stable enterotoxins secreted by E. Additionally we are shipping PDZ Domain Containing 3 Antibodies (44) and PDZ Domain Containing 3 Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat PDZD3 PDZD3 500986  
PDZD3 79849 Q86UT5
PDZD3 170761 Q99MJ6
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Top PDZ Domain Containing 3 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

PDZD3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for PDZ Domain Containing 3 (PDZD3) Interaction Partners

Human PDZ Domain Containing 3 (PDZD3) interaction partners

  1. The NHERF4 is a novel modulator of luminal fluidity in the intestine by adjusting SLC26A3 (show SLC26A3 Proteins) expression and activity through a phosphorylation-dependent mechanism.

  2. IKEPP was also found to be expressed in vascular endothelial cells where it co-localizes and complexes with the hIP

  3. A novel PDZ protein regulates the activity of guanylyl cyclase C (show GUCY2C Proteins), the heat-stable enterotoxin receptor (show GUCY2C Proteins).

  4. Regulation of NHE3 (show SLC9A3 Proteins) depends on the nature of the NHERF (show SLC9A3R1 Proteins) family member associating with NHE3 (show SLC9A3 Proteins) and the accompanying NHE3 (show SLC9A3 Proteins) complexes.

Mouse (Murine) PDZ Domain Containing 3 (PDZD3) interaction partners

  1. Regulation of NHE3 (show SLC9A3 Proteins) depends on the nature of the NHERF (show SLC9A3R1 Proteins) family member associating with NHE3 (show SLC9A3 Proteins) and the accompanying NHE3 (show SLC9A3 Proteins) complexes.[IKEPP]

  2. PDZK2 is an essential TRPV6 (show TRPV6 Proteins) interacting protein as a physiological modulator of TRPV6 (show TRPV6 Proteins).

PDZ Domain Containing 3 (PDZD3) Protein Profile

Protein Summary

Guanylyl cyclase C (GCC, or GUCY2C\; MIM 601330) produces cGMP following the binding of either endogenous ligands or heat-stable enterotoxins secreted by E. coli and other enteric bacteria. Activation of GCC initiates a signaling cascade that leads to phosphorylation of the cystic fibrosis transmembrane conductance regulator (CFTR\; MIM 602421), followed by a net efflux of ions and water into the intestinal lumen. IKEPP is a regulatory protein that associates with GCC and regulates the amount of cGMP produced following receptor stimulation (Scott et al., 2002

Gene names and symbols associated with PDZD3

  • PDZ domain containing 3 (Pdzd3)
  • PDZ domain containing 3b (pdzd3b)
  • PDZ domain containing 3 (PDZD3)
  • IKEPP protein
  • NaPi-Cap2 protein
  • NHERF4 protein
  • Pdzk2 protein
  • RGD1559807 protein
  • zgc:194812 protein

Protein level used designations for PDZD3

Na(+)/H(+) exchange regulatory cofactor NHE-RF4 , PDZ domain containing 3 , NHERF-4 , PDZ domain containing 2 , PDZ domain-containing protein 2 , PDZ domain-containing protein 3 , intestinal and kidney enriched PDZ protein , intestinal and kidney-enriched PDZ protein , na/Pi cotransporter C-terminal-associated protein 2 , naPi-Cap2 , natrium-phosphate cotransporter IIa C-terminal-associated protein 2 , sodium-hydrogen exchanger regulatory factor 4 , sodium-phosphate cotransporter IIa C-terminal-associated protein 2

GENE ID SPECIES
500986 Rattus norvegicus
566852 Danio rerio
79849 Homo sapiens
170761 Mus musculus
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