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PHD Finger Protein 6 (PHF6) ELISA Kits

PHF6 is a member of the plant homeodomain (PHD)-like finger (PHF) family. Additionally we are shipping PHF6 Antibodies (36) and PHF6 Proteins (7) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human PHF6 PHF6 84295 Q8IWS0
Anti-Mouse PHF6 PHF6 70998 Q9D4J7
Anti-Rat PHF6 PHF6 100359714  
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More ELISA Kits for PHF6 Interaction Partners

Human PHD Finger Protein 6 (PHF6) interaction partners

  1. Female phenotypes of Borjeson-Forssman-Lehmann syndrome patients with PHF6 mutations

  2. Our RBBP4 (show RBBP4 ELISA Kits)-PHF6 complex structure provides insights into the molecular basis of PHF6-NuRD complex interaction and implicates a role for PHF6 in chromatin structure modulation and gene regulation.

  3. Phf6 is a "lineage-specific" cancer gene that plays opposing roles in developmentally distinct hematopoietic malignancies.

  4. The PHF6 tumor suppressor gene was targeted in acute lymphoblastic leukemia by microRNA-128-3p.

  5. Our report confirms that PHF6 loss in females results in a recognizable phenotype overlapping with Coffin-Siris syndrome and distinct from Borjeson-Forssman-Lehmann syndrome.

  6. Recurrent microdeletion was detected in Xq26.3, causing loss of PHF6 expression, a potential tumor suppressor gene, and the miR (show MLXIP ELISA Kits)-424, which is involved in the development of acute myeloid leukemia (show BCL11A ELISA Kits).

  7. The findings show that de novo mutations in PHF6 in females result in a recognisable phenotype which overlap with Borjeson-Forssman-Lehmann syndrome but also has additional distinct features, thus adding a new facet to this disorder.

  8. these data support the hypothesis that PHF6 may function as a transcriptional repressor using its ePHD domains binding to the promoter region of its repressed gene

  9. Data suggest that mutations of PHF6 are associated with chronic myeloid leukemia (CML) progression.

  10. These results reveal that the key function of PHF6 is involved in regulating rRNA synthesis, which may contribute to its roles in cell cycle control, genomic maintenance, and tumor suppression.

Mouse (Murine) PHD Finger Protein 6 (PHF6) interaction partners

  1. These results place miR (show MLXIP ELISA Kits)-128 upstream of PHF6 in a pathway vital for cortical lamination as well as for the development of neuronal morphology and intrinsic excitability.

  2. As part of a cell-intrinsic transcriptional pathway, PHF6 regulates neuronal migration in the brain.

  3. Strongest Phf6 gene expression and nuclear localisation of Phf6 protein were observed in the developing central nervous system, the anterior pituitary gland, the primordia of facial structures and the limb buds.

PHF6 Antigen Profile

Antigen Summary

This gene is a member of the plant homeodomain (PHD)-like finger (PHF) family. It encodes a protein with two PHD-type zinc finger domains, indicating a potential role in transcriptional regulation, that localizes to the nucleolus. Mutations affecting the coding region of this gene or the splicing of the transcript have been associated with Borjeson-Forssman-Lehmann syndrome (BFLS), a disorder characterized by mental retardation, epilepsy, hypogonadism, hypometabolism, obesity, swelling of subcutaneous tissue of the face, narrow palpebral fissures, and large ears. Alternate splicing results in multiple transcript variants, encoding different isoforms.

Gene names and symbols associated with PHD Finger Protein 6 (PHF6) ELISA Kits

  • PHD finger protein 6 (phf6) antibody
  • PHD finger protein 6 (PHF6) antibody
  • PHD finger protein 6 (LOC100225613) antibody
  • PHD finger protein 6 (LOC100346149) antibody
  • PHD finger protein 6 (Phf6) antibody
  • 2700007B13Rik antibody
  • 4931428F02Rik antibody
  • BFLS antibody
  • BORJ antibody
  • CENP-31 antibody
  • mKIAA1823 antibody
  • wu:fa22g03 antibody
  • zgc:55403 antibody

Protein level used designations for PHD Finger Protein 6 (PHF6) ELISA Kits

PHD finger protein 6 , PHD-like zinc finger protein , centromere protein 31

GENE ID SPECIES
327070 Danio rerio
495066 Xenopus laevis
707390 Macaca mulatta
779543 Xenopus (Silurana) tropicalis
100151997 Sus scrofa
100225613 Taeniopygia guttata
100346149 Oryctolagus cuniculus
100379647 Monodelphis domestica
735789 Pan troglodytes
100054177 Equus caballus
84295 Homo sapiens
422235 Gallus gallus
612921 Canis lupus familiaris
518186 Bos taurus
70998 Mus musculus
100359714 Rattus norvegicus
100174671 Pongo abelii
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