POU Class 3 Homeobox 2 Proteins (POU3F2)

POU3F2 encodes a member of the POU-III class of neural transcription factors. Additionally we are shipping POU3F2 Antibodies (100) and POU3F2 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
POU3F2 12307 P12658
POU3F2 5454 P20265
POU3F2 29588 P56222
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Top POU3F2 Proteins at antibodies-online.com

Showing 7 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
Yeast Zebrafish His tag   1 mg Log in to see 60 to 71 Days
Yeast Xenopus laevis His tag   1 mg Log in to see 60 to 71 Days
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days

POU3F2 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
, ,
Rat (Rattus)

More Proteins for POU Class 3 Homeobox 2 (POU3F2) Interaction Partners

Mouse (Murine) POU Class 3 Homeobox 2 (POU3F2) interaction partners

  1. propose that chronic suppression of calbindin (show CALB1 Proteins) by DeltaFosB is one mechanism through which intermittent seizures drive persistent cognitive deficits in conditions accompanied by recurrent seizures

  2. This study investigated changes in the skin in the K5-Brn2 transgenic mouse, which overexpresses Brn2 and contains the keratin 5 promotor. The volume of the eccrine glands was reduced in the K5-Brn2 transgenic mouse.

  3. Our results demonstrate that fear memory and social behavior are altered in male knockout mice, and Calb1 (show CALB1 Proteins) KO mice of both sexes show less anxiety. Moreover, gene expression studies of the amygdala and prefrontal cortex revealed several significant genotype and sex effects in genes related to brain-derived neurotrophic factor (show BDNF Proteins) signaling, hormone receptors, histone deacetylases, and gamma-aminobutyric acid signaling.

  4. Microgravity causes substantial down-regulation of nerve tissue proteins, choline acetyltransferase, NF200 (show NEFH Proteins), and calbindin (show CALB1 Proteins) in mouse motor neurons.

  5. results suggest that a mutually repressive mechanism exists between Brn1 (show POU3F3 Proteins)/2 and Rorb (show RORB Proteins) expression and that the established expression of Brn1 (show POU3F3 Proteins)/2 and Rorb (show RORB Proteins) further specifies those neurons into L2/3 and L4, respectively, during UCP (show UCP1 Proteins) maturation

  6. Calbindin D-28k (show CALB1 Proteins) plays an important role in gene expression of distal kidney tubule Ca, but not Mg, transport molecules.

  7. Mammalian-specific sequences in pou3f2 contribute to maternal behavior.

  8. Brn2-Zic1 (show ZIC1 Proteins) axis is essential to specify neural fate in retinoic-acid-treated embryonic stem cells.

  9. calbindin1 in rat primary islet cells reduced glucose-stimulated insulin (show INS Proteins) secretion (GSIS), and the effect of BMP4 (show BMP4 Proteins) on GSIS was lost in islets from calbindin1 (Calb1 (show CALB1 Proteins)) knockout mice

  10. These results indicate that changes of CB protein expression may be associated with no neuronal death in the model of neuroinflammation with systemic administration of 1 mg/kg LPS (show TLR4 Proteins).

Human POU Class 3 Homeobox 2 (POU3F2) interaction partners

  1. Re4sults show that BRN2 is: directly transcriptionally repressed by AR, required for the expression of terminal neuroendocrine markers and aggressive growth of castration-resistant prostate cancer (CRPC), and is highly expressed in human neuroendocrine prostate cancer and metastatic CRPC with low circulating PSA.

  2. These findings not only shed light on the molecular mechanism of the anticancer properties of capsaicin, but also the transcription regulation of tNOX (show ENOX2 Proteins) expression that may potentially explain how POU3F2 is associated with tumorigenesis.

  3. Data indicate that NFIB (show NFIB Proteins) protein increases EZH2 (show EZH2 Proteins) protein expression downstream of BRN2 protein, which further decreases MITF (show MITF Proteins) protein levels.

  4. We show that POU3F2 lies downstreamof SIM1 and controls oxytocin expression in the hypoth (show SIM1 Proteins)alamic neuroendocrine preoptic area. We show that this finding is consistent with the expression patterns of POU3F2 and related genes in the human brain.

  5. BRN2 is a higher level regulator than ASCL1 and ND1 and BRN2 might be involved in aggressiveness of small cell lung cancer.

  6. TTF1 expression in small-cell lung cancer is a cell lineage-specific phenomenon that involves the developing neural cell-specific homeoprotein BRN2.

  7. The present study investigated transcriptional regulation of CDH13 (show CDH13 Proteins) in melanoma. Found an inverse correlation between BRN2 and T-cadherin (show CDH13 Proteins) protein and transcript expression in melanoma.

  8. PI3K (show PIK3CA Proteins) has a crucial role in regulating Brn-2 and Pax3 (show PAX3 Proteins) expression and neoplasm invasiveness, and it is a key determinant of melanoma subpopulation diversity.

  9. links BRN2 as an activator and MITF (show MITF Proteins) as a repressor of the NOTCH (show NOTCH1 Proteins) pathway in melanoma cells. Loss of the BRN2-MITF (show MITF Proteins) axis in antisense-ablated cell lines decreased the melanoma sphere-forming capability and cell adhesion

  10. a model for the apparent non-overlapping expression levels of BRN2 and MITF (show MITF Proteins) in melanoma, mediated by miR (show MLXIP Proteins)-211 expression.

Zebrafish POU Class 3 Homeobox 2 (POU3F2) interaction partners

  1. Using morpholino and mutant zebrafish models, we show that POU3F2 lies downstream of SIM1 and controls oxytocin expression in the hypothalamic neuroendocrine preoptic area.

POU3F2 Protein Profile

Protein Summary

This gene encodes a member of the POU-III class of neural transcription factors. The encoded protein is involved in neuronal differentiation and enhances the activation of corticotropin-releasing hormone regulated genes. Overexpression of this protein is associated with an increase in the proliferation of melanoma cells.

Gene names and symbols associated with POU3F2

  • calbindin 1 (Calb1)
  • POU class 3 homeobox 2 L homeolog (pou3f2.L)
  • POU class 3 homeobox 2 (POU3F2)
  • POU class 3 homeobox 2 (Pou3f2)
  • POU class 3 homeobox 2b (pou3f2b)
  • POU domain, class 3, transcription factor 2 (Pou3f2)
  • 9430075J19Rik protein
  • A230098E07Rik protein
  • Brain-2 protein
  • Brn-2 protein
  • Brn2 protein
  • Calb protein
  • Calb-1 protein
  • CB protein
  • N-Oct3 protein
  • oct-7 protein
  • OCT7 protein
  • OTF-7 protein
  • Otf7 protein
  • pou3f2 protein
  • pou3f2-A protein
  • pou3f4 protein
  • pou47 protein
  • POUF3 protein
  • XlPOU3 protein
  • zp47 protein
  • zp47pou protein

Protein level used designations for POU3F2

CalbindinD28K , D-28K , PCD-29 , calbindin , calbindin 1, 28kDa , calbindin D28 , calbindin-28K , calbindin-D (28k) , spot 35 protein , vitamin D-dependent calcium-binding protein, avian-type , POU domain, class 3, transcription factor 2-B , POU domain, class 3, transcription factor 4 , transcription factor POU3-B , xlPOU3B , POU domain, class 3, transcription factor 2 , brain-2 , brain-specific homeobox/POU domain protein 2 , nervous system-specific octamer-binding transcription factor N-Oct-3 , octamer-binding protein 7 , octamer-binding transcription factor 7 , POU class 3 homeobox 2 , protein Brn-2 , POU domain gene 47 , POU domain protein 47 , POU domain protein ZP-47 , ZP-47 , brain-2 class III POU-domain protein

12307 Mus musculus
779122 Xenopus laevis
5454 Homo sapiens
481931 Canis lupus familiaris
783320 Bos taurus
29588 Rattus norvegicus
100157279 Sus scrofa
30397 Danio rerio
18992 Mus musculus
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