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POU Domain, Class 4, Transcription Factor 1 Proteins (POU4F1)

POU4F1 encodes a member of the POU-IV class of neural transcription factors. Additionally we are shipping POU4F1 Antibodies (34) and POU4F1 Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
POU4F1 5457 Q01851
POU4F1 114503  
POU4F1 18996 P17208
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Top POU4F1 Proteins at antibodies-online.com

Showing 6 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Chicken His tag   1 mg Log in to see 56 to 66 Days
$2,225.67
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,262.33
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

POU4F1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Rat (Rattus)

Mouse (Murine)

More Proteins for POU Domain, Class 4, Transcription Factor 1 (POU4F1) Interaction Partners

Human POU Domain, Class 4, Transcription Factor 1 (POU4F1) interaction partners

  1. Brn3a cooperates with activated RAS/RAF (show RAF1 Proteins) signalling by reducing oncogene (show RAB1A Proteins)-induced senescence in melanocytic tumourigenesis.

  2. Data indicate that median methylation levels of BCAN (show BCAN Proteins), HOXD1 (show HOXD1 Proteins), KCTD8 (show KCTD8 Proteins), KLF11 (show KLF11 Proteins), NXPH1 (show NXPH1 Proteins), POU4F1, SIM1 (show SIM1 Proteins), and TCF7L1 (show TCF3 Proteins) were >/=30% higher than in normal samples, representing potential biomarkers for tumor diagnosis.

  3. PoU4F1 is highly expressed in t(8;21) samples, with AML (show RUNX1 Proteins)/ETO (show RUNX1T1 Proteins) appearning to promote some BRN3A expression

  4. BRN3A possesses anti-apoptotic property, and considering the above results, it may be regarded as the key component in promoting tumorigenic growth in the uterine cervical cells.

  5. Ewing sarcoma induce expression of neuronal markers such as BRN3A showing that the function of those same markers may be restricted or controlled in an sarcoma-dependent manner.

  6. Dysregulation of POU4F1 is associated with t(8;21) acute myeloid leukemia (show BCL11A Proteins).

  7. genomic organization of the Brn-3a locus and the mechanisms that control the expression of two different proteins from one genomic locus

  8. Measurement of Brn-3a levels in smears can be used to detect a significant proportion of cervical lesions that were missed by Pap (show REG3A Proteins) smear.

  9. These results indicate that Brn-3a could play an important role in the near future in improving cervical cancer screening.

  10. oncogenic rearrangement of EWS (show EWSR1 Proteins) to produce EWS (show EWSR1 Proteins)/Fli-1 (show FLI1 Proteins) may enhance the antiapoptotic effect of Brn-3a and inhibit its ability to promote neuronal differentiation.

Pig (Porcine) POU Domain, Class 4, Transcription Factor 1 (POU4F1) interaction partners

  1. Brn-3a may play a hitherto uncharacterized role in protection of sensory neurons from alphaherpesvirus-induced cell death, which may have implications for different aspects of the alphaherpesvirus life cycle, including latency/reactivation events

Mouse (Murine) POU Domain, Class 4, Transcription Factor 1 (POU4F1) interaction partners

  1. Study demonstrates a sequential expression order of NEUROD1 (show NEUROD1 Proteins)>ISL1 (show ISL1 Proteins)>POU4F1>POU4F2 (show POU4F2 Proteins) during the inner ear neurogenesis.

  2. Pou4f1 and pou4f2 (show POU4F2 Proteins) are dispensable for the long-term survival of adult retinal ganglion cells in mice.

  3. The deficiency of Pou4f1 who perform poorly in motivation-based locomotor behaviors, such as voluntary wheel running and the accelerating rotarod, but show only minor abnormalities in gait and balance and exhibit normal levels of basal locomotion.

  4. Data indicate that Brn3 transcription factors Brn3b (show POU4F2 Proteins) affects Brn3a and Brn3c (show POU4F3 Proteins) positive Retinal Ganglion Cells (RGCs) in cell autonomous and non-cell autonomous fashion.

  5. The results demonstrated a critical role for Brn3a in generating dorsal root ganglia sensory neuron diversity and regulating sensory afferent projections to the central targets.

  6. neither Brn3a nor Brn3c (show POU4F3 Proteins) are expressed in intrinsically photosensitive retinal ganglion cells

  7. Brn3 gene expression patterns in the retina and inner ear, these experiments suggest a deep functional similarity among primary somatosensory neurons, spiral and vestibular ganglion neurons, and retinal ganglion cells

  8. Progressive increase in IOP and loss of Brn3a signals in D2 animals were consistent with glaucoma progression starting after 6 months of age.

  9. An epistatic interaction between Brn3a and Isl1 (show ISL1 Proteins) is key to sensory neuron specification, in their absence almost all known markers of sensory neurons are lost. Data support the hypothesis that Brn3a and Isl1 (show ISL1 Proteins) bind to shared enhancers in target genes.

  10. Data show a longitudinal domain positive for both Nkx6.1 (show NKX6-1 Proteins) and Nkx6.2 that is medial to the Pou4f1-positive red nucleus. This domain could correspond to part of the reticular formation, which extends from the diencephalon and the mesencephalon.

POU4F1 Protein Profile

Protein Summary

This gene encodes a member of the POU-IV class of neural transcription factors. This protein is expressed in a subset of retinal ganglion cells and may be involved in the developing sensory nervous system. This protein may also promote the growth of cervical tumors. A translocation of this gene is associated with some adult acute myeloid leukemias.

Gene names and symbols associated with POU4F1

  • POU domain, class 4, transcription factor 1 (Tsp_01181)
  • POU class 4 homeobox 1 (pou4f1)
  • POU class 4 homeobox 1 (POU4F1)
  • POU class 4 homeobox 1 (Pou4f1)
  • POU class 4 homeobox 1 like (POU4F1AL)
  • POU domain, class 4, transcription factor 1 (pou4f1)
  • POU domain, class 4, transcription factor 1 (Pou4f1)
  • Brn-3 protein
  • Brn-3.0 protein
  • Brn-3a protein
  • Brn3 protein
  • brn3.0 protein
  • Brn3a protein
  • brn3a-A protein
  • E130119J07Rik protein
  • Oct-T1 protein
  • POU4F1 protein
  • RDC-1 protein

Protein level used designations for POU4F1

POU domain, class 4, transcription factor 1 , class IV POU-homeodomain protein , brain-3A , brain-specific homeobox/POU domain protein 3A , homeobox/POU domain protein RDC-1 , POU class 4 homeobox 1 , POU domain factor , brain-specific homeobox/POU domain protein 3a , brn3b , etID22526.1 , brn-3A

GENE ID SPECIES
10905375 Trichinella spiralis
373813 Xenopus laevis
5457 Homo sapiens
610785 Canis lupus familiaris
784887 Bos taurus
114503 Rattus norvegicus
448983 Sus scrofa
100857623 Gallus gallus
395739 Gallus gallus
58057 Danio rerio
18996 Mus musculus
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