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PRP31 Pre-MRNA Processing Factor 31 Homolog (S. Cerevisiae) Proteins (PRPF31)

PRPF31 encodes a component of the spliceosome complex and is one of several retinitis pigmentosa-causing genes. Additionally we are shipping PRP31 Pre-MRNA Processing Factor 31 Homolog (S. Cerevisiae) Antibodies (66) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PRPF31 26121 Q8WWY3
Rat PRPF31 PRPF31 292536  
PRPF31 68988 Q8CCF0
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Top PRP31 Pre-MRNA Processing Factor 31 Homolog (S. Cerevisiae) Proteins at antibodies-online.com

Showing 7 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
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Yeast Yeast His tag   1 mg Log in to see 56 to 66 Days
$3,399.00
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Yeast Xenopus tropicalis His tag   1 mg Log in to see 56 to 66 Days
$3,411.83
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Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$3,411.83
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HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
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PRPF31 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for PRP31 Pre-MRNA Processing Factor 31 Homolog (S. Cerevisiae) (PRPF31) Interaction Partners

Human PRP31 Pre-MRNA Processing Factor 31 Homolog (S. Cerevisiae) (PRPF31) interaction partners

  1. A PRPF31 mutation was identified to be responsible for adRP (show PLIN2 Proteins) in a large Chinese family. Our findings expand the mutation spectrum of RP in the Chinese population.

  2. A mutation in PRPF31 is hypostatic to a trait acting on CNOT3 (show CNOT3 Proteins), with the RP11 phenotype only being observed when there is homozygous (recessive) inheritance of the higher expressivity CNOT3 (show CNOT3 Proteins) ("symptomatic" or risk) allele.

  3. identification of the novel "A" insertion mutation in exon9 at chr19:54629961-54629961 in PRPF31 can provide further genetic evidence for clinical test for adRP (show PLIN2 Proteins) and JMD.

  4. Two novel PRPF31 mutations including a complex insertion-deletion mutation have been identified in Chinese families with retinitis pigmentosa.

  5. We have identified a novel 14-bp deletion in PRPF31 as the genetic driver of adRP (show PLIN2 Proteins) in a large Mexican family that exhibits nonpenetrance and variable expressivity, known properties of this locus.

  6. The molecular and clinical features of a family with a novel 3-base insertion, c.914_915insTGT (p.Val305_Asp306insVal) in exon 9 of PRPF31 are described to illustrate the salient clinical features of mutations in this gene.

  7. In asymptomatic carriers CNOT3 (show CNOT3 Proteins) is expressed at low levels, allowing higher amounts of wild-type PRPF31 transcripts to be produced and preventing manifestation of retinal degeneration.

  8. Novel PRPF31 mutations associated with Chinese autosomal dominant retinitis pigmentosa patients occur at a relatively high frequency.

  9. The present study describes mapping of a locus for non-syndromic adRP (show PLIN2 Proteins) at 19q13.42 (RP11 locus) in a family of Indian origin and identifies a novel deletion, c.59_65del7, in PRPF31 within the mapped interval.

  10. Characterization of the core promoters controlling the expression of PRPF31 and TFPT (show TFPT Proteins), a bi-directional gene-pair.

Mouse (Murine) PRP31 Pre-MRNA Processing Factor 31 Homolog (S. Cerevisiae) (PRPF31) interaction partners

  1. The mouse retinal pigment epithelium (RPE (show RPE Proteins))is the primary cell affected by mutations in the RNA splicing factors (PRPF3 (show PRPF3 Proteins), PRPF8, and PRPF31), and these changes occur at an early age.

  2. found that PRP31 and PRPC8 as well as snRNAs are highly expressed in retinal cells

  3. CTNNBL1 (show CTNNBL1 Proteins) is a novel nuclear localization sequence-binding protein that recognizes RNA-splicing factors CDC5L (show CDC5L Proteins) and Prp31

  4. The finding of similar degenerative changes in RPE (show RPE Proteins) cells of all three mouse models suggests that the retinal pigment epithelium may be the primary cell type affected in the RNA splicing factor (show SLU7 Proteins) forms of retinitis pigmentosa.

  5. Our results demonstrate that mutations in PRPF31 gene affect rhodopsin (RHO) pre-mRNA splicing and reveal a link between PRPF31 and RHO, two major genes in autosomal dominant retinitis pigmentosa.

  6. Our results indicate that PRPF31 mutations lead to defective pre-mRNA splicing of photoreceptor-specific genes and that the ubiquitously expressed adRP (show PLIN2 Proteins) gene, PRPF31, is critical for pre-mRNA splicing of a subset of photoreceptor genes.

  7. The results imply that Prpf31 is necessary for survival, and there is no compensation mechanism in mouse for the lack of this splicing factor (show SLU7 Proteins)

PRP31 Pre-MRNA Processing Factor 31 Homolog (S. Cerevisiae) (PRPF31) Protein Profile

Protein Summary

This gene encodes a component of the spliceosome complex and is one of several retinitis pigmentosa-causing genes. When the gene product is added to the spliceosome complex, activation occurs.

Gene names and symbols associated with PRPF31

  • PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae) (PRPF31)
  • pre-mRNA processing factor 31 (prpf31)
  • PrpF31 U4/U6*U5 snRNP-associated pre-mRNA processing factor 31, (IC) (PrpF31)
  • PRP31 pre-mRNA processing factor 31 homolog (PRPF31)
  • pre-mRNA processing factor 31 (PRPF31)
  • pre-mRNA processing factor 31 (Prpf31)
  • PRP31 pre-mRNA processing factor 31 homolog (yeast) (Prpf31)
  • PRP31 pre-mRNA processing factor 31 homolog (yeast) (prpf31)
  • 1500019O16Rik protein
  • 2810404O06Rik protein
  • AW554706 protein
  • DDBDRAFT_0219465 protein
  • DDBDRAFT_0304959 protein
  • DDB_0219465 protein
  • DDB_0304959 protein
  • NY-BR-99 protein
  • prp31 protein
  • PRPF31 protein
  • rp11 protein
  • SNRNP61 protein
  • zgc:66177 protein

Protein level used designations for PRPF31

pre-mRNA processing factor 31 homolog , PrpF31 U4/U6*U5 snRNP-associated pre-mRNA processing factor 31, (IC) , PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae) , PRP31 pre-mRNA processing factor 31 homolog , u4/U6 small nuclear ribonucleoprotein Prp31-like , U4/U6 small nuclear ribonucleoprotein Prp31 , U4/U6 snRNP 61 kDa protein , hPrp31 , pre-mRNA-processing factor 31 , protein 61K , serologically defined breast cancer antigen NY-BR-99 , pre-mRNA processing factor 31-like protein

GENE ID SPECIES
456278 Pan troglodytes
8627218 Dictyostelium discoideum AX4
9832603 Ostreococcus tauri
100019854 Monodelphis domestica
100049878 Equus caballus
100137336 Papio anubis
100455616 Pongo abelii
26121 Homo sapiens
292536 Rattus norvegicus
495301 Xenopus laevis
476389 Canis lupus familiaris
513577 Bos taurus
68988 Mus musculus
393476 Danio rerio
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