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PAX3 is a member of the paired box (PAX) family of transcription factors. Additionally we are shipping Paired Box 3 Proteins (8) and Paired Box 3 Kits (1) and many more products for this protein.
Showing 10 out of 125 products:
Human Polyclonal PAX3 Primary Antibody for IHC, ELISA - ABIN185216
Tsukamoto, Nakamura, Niikawa: Isolation of two isoforms of the PAX3 gene transcripts and their tissue-specific alternative expression in human adult tissues. in Human genetics 1994
Show all 2 references for ABIN185216
Cow (Bovine) Polyclonal PAX3 Primary Antibody for EIA, IHC (p) - ABIN374426
Hsieh, Yao, Lai, Yang: Transcriptional repression activity of PAX3 is modulated by competition between corepressor KAP1 and heterochromatin protein 1. in Biochemical and biophysical research communications 2006
Show all 2 references for ABIN374426
Human Polyclonal PAX3 Primary Antibody for IF (p), IHC (p) - ABIN737616
Bonchak, Eby, Willenborg, Chrobak, Henning, Krzywiec, Johnson, Le Poole: Targeting melanocyte and melanoma stem cells by 8-hydroxy-2-dipropylaminotetralin. in Archives of biochemistry and biophysics 2014
Show all 2 references for ABIN737616
Human Polyclonal PAX3 Primary Antibody for EIA, WB - ABIN453251
Boutet, Disatnik, Chan, Iori, Rando: Regulation of Pax3 by proteasomal degradation of monoubiquitinated protein in skeletal muscle progenitors. in Cell 2007
Human Monoclonal PAX3 Primary Antibody for ELISA, WB - ABIN1724817
Dong, Li, Cao, Liu, Pier, Chen, Xu, Chen, Wang, Cui: FGF2 regulates melanocytes viability through the STAT3-transactivated PAX3 transcription. in Cell death and differentiation 2012
Chicken Polyclonal PAX3 Primary Antibody for IHC, WB - ABIN2777556
Blake, Ziman: Pax3 transcripts in melanoblast development. in Development, growth & differentiation 2005
Chicken Polyclonal PAX3 Primary Antibody for WB - ABIN2779649
Wachtel, Dettling, Koscielniak, Stegmaier, Treuner, Simon-Klingenstein, Bühlmann, Niggli, Schäfer: Gene expression signatures identify rhabdomyosarcoma subtypes and detect a novel t(2;2)(q35;p23) translocation fusing PAX3 to NCOA1. in Cancer research 2004
Chicken Polyclonal PAX3 Primary Antibody for WB - ABIN2779648
Mercado, Xia, Zhang, Ahn, Gustafson, Laé, Ladanyi, Barr: Identification of PAX3-FKHR-regulated genes differentially expressed between alveolar and embryonal rhabdomyosarcoma: focus on MYCN as a biologically relevant target. in Genes, chromosomes & cancer 2008
A novel missense variant, PAX3:p.Pro32Arg, in Appaloosa horses with a splashed white phenotype in addition to their leopard complex spotting patterns.
several independent mutations in MITF (show MITF Antibodies) and PAX3 together with known variants in the EDNRB (show EDNRB Antibodies) and KIT genes explain a large proportion of horses with the more extreme white spotting phenotypes
The pax3 and Pax7 (show PAX7 Antibodies) paralogs cooperate in neural and neural crest patterning using distinct molecular mechanisms, in Xenopus laevis embryos.
FOXD3 (show FOXD3 Antibodies) is sufficient but not necessary to drive PAX3 expression in melanoma cells.
Secreted Frizzled-Related Protein 3 (SFRP3 (show FRZB Antibodies)) Is Required for Tumorigenesis of PAX3-FOXO1 (show FOXO1 Antibodies)-Positive Alveolar Rhabdomyosarcoma
findings suggest a tumor suppressor role for APC (show APC Antibodies)/C(Cdh1 (show CDH1 Antibodies)) in melanocytes and that targeting PAX3 may be a strategy for treating melanoma.
PAX3 phosphorylation has a role in determing melanoma phenotypes by affecting proliferation, invasion, and transformation
All affected members of pedigree IR-WS-20 carried the mutation c.1024_1040 del AGCACGATTCCTTCCAA in exon 7 of PAX3, while none of the unaffected members and 50 of the ethnic matched controls tested had this deletion.
PAX3 differentially regulates various downstream target genes involved in cell proliferation in melanoma cells compared to melanocytes.
The results expand the spectrum of PAX3 mutations and may have implications for the genetic counseling of Waardenburg syndrome in Iran.
Report novel PAX3-NCOA1 (show NCOA1 Antibodies) gene fusions in biphenotypic sinonasal sarcomas with focal rhabdomyoblastic differentiation.
PAX3-FOXO1 (show FOXO1 Antibodies) may contribute to tumor formation.
Data show that transcription factors PAX3 and FOXD3 (show FOXD3 Antibodies)-mediated melanoma cell migration is dependent on promoting the expression of chemokine receptor CXCR4 (show CXCR4 Antibodies).
SNP and haplotype analysis of PAX3 gene provide evidence for association with growth traits in Chinese cattle.
PAX3 role in neural tube defects
The Pax3(GFP) allele proved to be a convenient marker to identify and directly sort heterogeneous populations of melanoma cells within the tumor bulk at each stage of melanoma progression.
deletion of Foxc1 (show FOXC1 Antibodies) and Foxc2 (show FOXC2 Antibodies) specifically in Pax3-positive cells affects cell fate choices in the dermomyotome of somites at forelimb level, promoting the myogenic cell fate at the expense of endothelial cells that migrate to the limb
These results demonstrate a requirement for endoglin (show ENG Antibodies) in descendants of Pax3-expressing vascular cell precursors.
Results suggest that regional Pax3 expression not only marks a novel subset of High-grade Brainstem Glioma but also contributes to PDGF-B (show PDGFB Antibodies)-induced brainstem gliomagenesis
we show that the ability of Pax3 to induce the skeletal myogenic cell fate occurs at the expenses of the cardiac lineage.
Pax3 activity is regulated by the Hippo pathway and Pax (show PXN Antibodies) factors are Hippo effectors.
Loss of Pax3 expression is associated with craniofacial abnormalities.
the PAX3-NCOA2 (show NCOA2 Antibodies) fusion gene has a dual role in the tumorigenesis of rhabdomyosarcoma
BMP, Wnt (show WNT2 Antibodies) and FGF signaling are needed for expression of the neural plate border specifiers pax3a and zic3 (show ZIC3 Antibodies) in zebrafish
evidence of YAP's role in regulating pax3 neural crest expression
Pax3 in zebrafish is required for specification of two specific lineages of neural crest, xanthophores and enteric neurons.
This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2\;13)(q35\;q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini.
paired box 3
, paired box protein 3
, paired box gene 3 (Waardenburg syndrome 1)
, Paired-domain transcription factor Pax3
, Waardenburg syndrome 1
, paired box protein Pax-3
, paired-box 3
, paired box protein Pax-3-like
, paired box 3 b
, paired box protein Pax-3-B
, paired-domain transcription factor Pax3-B
, paired box gene 3
, paired box homeotic gene 3
, paired domain gene 3
, paired domain gene HuP2
, paired-box 3 protein
, homeodomain protein PAX3