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anti-Paired Box 3 (PAX3) Antibodies

PAX3 is a member of the paired box (PAX) family of transcription factors. Additionally we are shipping Paired Box 3 Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PAX3 5077 P23760
PAX3 114502  
PAX3 18505 P24610
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Top anti-Paired Box 3 Antibodies at antibodies-online.com

Showing 10 out of 102 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-PAX3 Antibody Titration: 0.2-1 ug/mlPositive Control: Hela cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Chicken Rabbit Un-conjugated IHC, WB Sample Type: Mouse B16F10 Primary Antibody Dilution: 1:200Secondary Antibody: Goat anti-rabbit-FITC Secondary Antibody Dilution: 1:000Color/Signal Descriptions: Green: FITC Blue: DAPI  Gene Name: PAX3 Submitted by: Tsu Fang Wu, Institute of Molecular Biology, National Chung Hsing University WB Suggested Anti-PAX3 Antibody  Positive Control: Lane 1: Flag-PAX3(overexpression, human), HEK293, 50?g. Lane 2: Mouse, B16F10, 50?g. Lane 3: Human, A375, 50?g. Lane 4: Human, A2058, 50?g Primary Antibody Dilution: 1:5000Secondary Antibody: Goat anti-rabbit APSecondry  Antibody Dilution: 1:0000Submitted by: Tsu Fang Wu, Institute of Molecular Biology, National Chung Hsing University 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Goat Un-conjugated EIA, IHC (p) 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Chicken Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Goat Un-conjugated IHC, ELISA, WB ABIN185216 (3µg/ml) staining of paraffin embedded Human Oesophagus. Microwaved antigen retrieval with Tris/EDTA buffer pH9, HRP-staining. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of PAX3 Antibody (N-term) (ABIN389492) in K562 cell line lysates (35 µg/lane). PAX3 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human skin reacted with PAX3 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of PAX3 Antibody (N-term) in K562 cell line lysates (35ug/lane). PAX3 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Human Mouse Un-conjugated ELISA, WB 0.1 mg Log in to see 3 to 4 Days
$430.10
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Lane 1: mouse embryo lysates Lane 2: human colon carcinoma lysates probed with Anti PAX3 Polyclonal Antibody, Unconjugated (ABIN737616) at 1:200 in 4C. Followed by conjugation to secondary antibody at 1:3000 90min in 37C. Predicted band 53kD. Observed band size: 53kD Formalin-fixed and paraffin embedded human esophageal carcinoma labeled with Anti-PAX3 Polyclonal Antibody, Unconjugated (ABIN737616) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Mouse Un-conjugated IHC (p), WB 50 μg Log in to see 6 to 8 Days
$500.50
Details

PAX3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Paired Box 3 Antibodies

  1. Cow (Bovine) Polyclonal PAX3 Primary Antibody for EIA, IHC (p) - ABIN374426 : Hsieh, Yao, Lai, Yang: Transcriptional repression activity of PAX3 is modulated by competition between corepressor KAP1 and heterochromatin protein 1. in Biochemical and biophysical research communications 2006 (PubMed)
    Show all 2 references for ABIN374426

  2. Human Polyclonal PAX3 Primary Antibody for IHC, ELISA - ABIN185216 : Tsukamoto, Nakamura, Niikawa: Isolation of two isoforms of the PAX3 gene transcripts and their tissue-specific alternative expression in human adult tissues. in Human genetics 1994 (PubMed)
    Show all 2 references for ABIN185216

  3. Human Monoclonal PAX3 Primary Antibody for ELISA, WB - ABIN1724817 : Dong, Li, Cao, Liu, Pier, Chen, Xu, Chen, Wang, Cui: FGF2 regulates melanocytes viability through the STAT3-transactivated PAX3 transcription. in Cell death and differentiation 2012 (PubMed)

  4. Human Polyclonal PAX3 Primary Antibody for IF (p), IHC (p) - ABIN737616 : Bonchak, Eby, Willenborg, Chrobak, Henning, Krzywiec, Johnson, Le Poole: Targeting melanocyte and melanoma stem cells by 8-hydroxy-2-dipropylaminotetralin. in Archives of biochemistry and biophysics 2014 (PubMed)

  5. Human Polyclonal PAX3 Primary Antibody for EIA, WB - ABIN453251 : Boutet, Disatnik, Chan, Iori, Rando: Regulation of Pax3 by proteasomal degradation of monoubiquitinated protein in skeletal muscle progenitors. in Cell 2007 (PubMed)

  6. Chicken Polyclonal PAX3 Primary Antibody for WB - ABIN2779649 : Wachtel, Dettling, Koscielniak, Stegmaier, Treuner, Simon-Klingenstein, Bühlmann, Niggli, Schäfer: Gene expression signatures identify rhabdomyosarcoma subtypes and detect a novel t(2;2)(q35;p23) translocation fusing PAX3 to NCOA1. in Cancer research 2004 (PubMed)

  7. Chicken Polyclonal PAX3 Primary Antibody for IHC, WB - ABIN2777556 : Blake, Ziman: Pax3 transcripts in melanoblast development. in Development, growth & differentiation 2005 (PubMed)

  8. Chicken Polyclonal PAX3 Primary Antibody for WB - ABIN2779648 : Mercado, Xia, Zhang, Ahn, Gustafson, Laé, Ladanyi, Barr: Identification of PAX3-FKHR-regulated genes differentially expressed between alveolar and embryonal rhabdomyosarcoma: focus on MYCN as a biologically relevant target. in Genes, chromosomes & cancer 2008 (PubMed)

More Antibodies against Paired Box 3 Interaction Partners

Horse (Equine) Paired Box 3 (PAX3) interaction partners

  1. A novel missense variant, PAX3:p.Pro32Arg, in Appaloosa horses with a splashed white phenotype in addition to their leopard complex spotting patterns.

  2. several independent mutations in MITF (show MITF Antibodies) and PAX3 together with known variants in the EDNRB (show EDNRB Antibodies) and KIT genes explain a large proportion of horses with the more extreme white spotting phenotypes

Xenopus laevis Paired Box 3 (PAX3) interaction partners

  1. The pax3 and Pax7 (show PAX7 Antibodies) paralogs cooperate in neural and neural crest patterning using distinct molecular mechanisms, in Xenopus laevis embryos.

Human Paired Box 3 (PAX3) interaction partners

  1. Secreted Frizzled-Related Protein 3 (SFRP3 (show FRZB Antibodies)) Is Required for Tumorigenesis of PAX3-FOXO1 (show FOXO1 Antibodies)-Positive Alveolar Rhabdomyosarcoma

  2. findings suggest a tumor suppressor role for APC (show APC Antibodies)/C(Cdh1 (show CDH1 Antibodies)) in melanocytes and that targeting PAX3 may be a strategy for treating melanoma.

  3. PAX3 phosphorylation has a role in determing melanoma phenotypes by affecting proliferation, invasion, and transformation

  4. All affected members of pedigree IR-WS-20 carried the mutation c.1024_1040 del AGCACGATTCCTTCCAA in exon 7 of PAX3, while none of the unaffected members and 50 of the ethnic matched controls tested had this deletion.

  5. PAX3 differentially regulates various downstream target genes involved in cell proliferation in melanoma cells compared to melanocytes.

  6. The results expand the spectrum of PAX3 mutations and may have implications for the genetic counseling of Waardenburg syndrome in Iran.

  7. Report novel PAX3-NCOA1 (show NCOA1 Antibodies) gene fusions in biphenotypic sinonasal sarcomas with focal rhabdomyoblastic differentiation.

  8. PAX3-FOXO1 (show FOXO1 Antibodies) may contribute to tumor formation.

  9. Data show that transcription factors PAX3 and FOXD3 (show FOXD3 Antibodies)-mediated melanoma cell migration is dependent on promoting the expression of chemokine receptor CXCR4 (show CXCR4 Antibodies).

  10. findings suggest that PAX3 WS mutants interfere with the normal functions of PAX3 in a dominant negative manner, which is important to the understanding of the pathogenesis of Waardenburg syndrome

Cow (Bovine) Paired Box 3 (PAX3) interaction partners

  1. SNP and haplotype analysis of PAX3 gene provide evidence for association with growth traits in Chinese cattle.

Mouse (Murine) Paired Box 3 (PAX3) interaction partners

  1. The Pax3(GFP) allele proved to be a convenient marker to identify and directly sort heterogeneous populations of melanoma cells within the tumor bulk at each stage of melanoma progression.

  2. deletion of Foxc1 (show FOXC1 Antibodies) and Foxc2 (show FOXC2 Antibodies) specifically in Pax3-positive cells affects cell fate choices in the dermomyotome of somites at forelimb level, promoting the myogenic cell fate at the expense of endothelial cells that migrate to the limb

  3. findings suggest a tumor suppressor role for APC (show APC Antibodies)/C(Cdh1 (show CDH1 Antibodies)) in melanocytes and that targeting PAX3 may be a strategy for treating melanoma.

  4. These results demonstrate a requirement for endoglin (show ENG Antibodies) in descendants of Pax3-expressing vascular cell precursors.

  5. Results suggest that regional Pax3 expression not only marks a novel subset of High-grade Brainstem Glioma but also contributes to PDGF-B (show PDGFB Antibodies)-induced brainstem gliomagenesis

  6. we show that the ability of Pax3 to induce the skeletal myogenic cell fate occurs at the expenses of the cardiac lineage.

  7. Pax3 activity is regulated by the Hippo pathway and Pax (show PXN Antibodies) factors are Hippo effectors.

  8. Loss of Pax3 expression is associated with craniofacial abnormalities.

  9. the PAX3-NCOA2 (show NCOA2 Antibodies) fusion gene has a dual role in the tumorigenesis of rhabdomyosarcoma

  10. positive input from the neural-specific transcription factor Sox2 (show SOX2 Antibodies). Altogether, our data provide important mechanistic insights into the coordinated integration of different signaling pathways on a short Pax3 CRM.

Zebrafish Paired Box 3 (PAX3) interaction partners

  1. BMP, Wnt (show WNT2 Antibodies) and FGF signaling are needed for expression of the neural plate border specifiers pax3a and zic3 (show ZIC3 Antibodies) in zebrafish

  2. evidence of YAP's role in regulating pax3 neural crest expression

  3. Pax3 in zebrafish is required for specification of two specific lineages of neural crest, xanthophores and enteric neurons.

Paired Box 3 (PAX3) Antigen Profile

Protein Summary

This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2\;13)(q35\;q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini.

Gene names and symbols associated with anti-Paired Box 3 (PAX3) Antibodies

  • paired box 3 (PAX3) antibody
  • paired box 3 (pax3) antibody
  • paired box 3 (pax3-b) antibody
  • paired box 3 (Pax3) antibody
  • paired box gene 3 (Pax3) antibody
  • paired box gene 3a (pax3a) antibody
  • CDHS antibody
  • HUP2 antibody
  • Pax-3 antibody
  • pax3 antibody
  • pax3b antibody
  • Sp antibody
  • splotch antibody
  • WS1 antibody
  • WS3 antibody
  • xpax3 antibody
  • xPax3-B antibody
  • zgc:92547 antibody

Protein level used designations for anti-Paired Box 3 (PAX3) Antibodies

paired box 3 , paired box protein 3 , paired box gene 3 (Waardenburg syndrome 1) , Paired-domain transcription factor Pax3 , Waardenburg syndrome 1 , paired box protein Pax-3 , paired-box 3 , paired box protein Pax-3-like , paired box 3 b , paired box protein Pax-3-B , paired-domain transcription factor Pax3-B , paired box gene 3 , paired box homeotic gene 3 , paired domain gene 3 , paired domain gene HuP2 , paired-box 3 protein , homeodomain protein PAX3 , etID309899.2

GENE ID SPECIES
414901 Sus scrofa
448464 Xenopus (Silurana) tropicalis
459971 Pan troglodytes
705315 Macaca mulatta
100056517 Equus caballus
100357318 Oryctolagus cuniculus
100406473 Callithrix jacchus
100468866 Ailuropoda melanoleuca
100560571 Anolis carolinensis
100591131 Nomascus leucogenys
496377 Xenopus laevis
374127 Gallus gallus
5077 Homo sapiens
488544 Canis lupus familiaris
540951 Bos taurus
114502 Rattus norvegicus
18505 Mus musculus
30532 Danio rerio
Selected quality suppliers for anti-Paired Box 3 (PAX3) Antibodies
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