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anti-Paired Box 5 (PAX5) Antibodies

PAX5 encodes a member of the paired box (PAX) family of transcription factors. Additionally we are shipping PAX5 Proteins (7) and PAX5 Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PAX5 5079 Q02548
PAX5 500453  
PAX5 18507 Q02650
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Top anti-PAX5 Antibodies at antibodies-online.com

Showing 10 out of 174 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated IHC, WB WB Suggested Anti-PAX5 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, WB PAX5 Antibody (Center) flow cytometric analysis of Ramos cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. PAX5 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PAX5 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p) Flow cytometric analysis of rabbit anti-PAX-5 (SP34) antibody in RAMOS (green) compare to negative control of rabbit IgG (blue). 7 mL Log in to see 2 to 3 Days
$302.00
Details
Human Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$456.50
Details
Human Rabbit Un-conjugated FACS, IHC (p) Flow cytometric analysis of rabbit anti-PAX-5 (SP34) antibody in RAMOS (green) compare to negative control of rabbit IgG (blue). 1 mL Log in to see 2 to 3 Days
$691.00
Details
Human Goat Un-conjugated ELISA, WB ABIN184804 staining (3µg/ml) of U937 lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Mouse Un-conjugated IHC, ELISA, WB Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10 ng), Green: Antigen (50ng), Blue: Antigen (100 ng) Figure 2: Immunohistochemical analysis of paraffin-embedded brain tumors tissues using PAX5 mouse mAb with DAB staining. 0.1 mg Log in to see 3 to 4 Days
$430.10
Details
Human Mouse Un-conjugated ELISA, WB Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 ng), Blue: Antigen (100 ng) Figure 2: Western blot analysis using PAX5 mouse mAb against Raji (1), and EVC-304 (2) cell lysate. 0.1 mg Log in to see 3 to 4 Days
$430.10
Details
Human Mouse Un-conjugated WB Western blot analysis of PAX5 over-expressed 293 cell line, cotransfected with PAX5 Validated Chimera RNAi used as specificity and loading control. Western Blot analysis of PAX5 expression in transfected 293T cell line by PAX5 monoclonal antibody (M01), clone 8F9. Lane 1: PAX5 transfected lysate(42.1 KDa). Lane 2: Non-transfected lysate. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details

PAX5 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-PAX5 Antibodies

  1. Human Monoclonal PAX5 Primary Antibody for IHC (p) - ABIN1687422 : Steinert, Schenkel, Fraser, Beura, Manlove, Igyártó, Southern, Masopust: Quantifying Memory CD8 T Cells Reveals Regionalization of Immunosurveillance. in Cell 2015 (PubMed)
    Show all 7 references for ABIN1687422

  2. Human Monoclonal PAX5 Primary Antibody for FACS, IHC (p) - ABIN1687411 : Zanelli, Valli, Capodanno, Ragazzi, Ascani: Anaplastic lymphoma kinase-positive large B-cell lymphoma: description of a case with an unexpected clinical outcome. in International journal of surgical pathology 2015 (PubMed)
    Show all 7 references for ABIN1687411

  3. Human Monoclonal PAX5 Primary Antibody for WB - ABIN394437 : Okamoto, Ogawa, Nowak, Kawamata, Akagi, Kato, Sanada, Weiss, Haferlach, Dugas, Ruckert, Haferlach, Koeffler: Genomic profiling of adult acute lymphoblastic leukemia by single nucleotide polymorphism oligonucleotide microarray and comparison to pediatric acute lymphoblastic leukemia. in Haematologica 2010 (PubMed)
    Show all 5 references for ABIN394437

  4. Human Polyclonal PAX5 Primary Antibody for EIA, WB - ABIN954009 : Song, Li, Tretiakova, Salgia, Cagle, Husain: Expression patterns of PAX5, c-Met, and paxillin in neuroendocrine tumors of the lung. in Archives of pathology & laboratory medicine 2010 (PubMed)
    Show all 5 references for ABIN954009

  5. Human Polyclonal PAX5 Primary Antibody for WB - ABIN493221 : Wallin, Wilting, Koseki, Fritsch, Christ, Balling: The role of Pax-1 in axial skeleton development. in Development (Cambridge, England) 1994 (PubMed)
    Show all 3 references for ABIN493221

  6. Human Monoclonal PAX5 Primary Antibody for ELISA, WB - ABIN969552 : Coyaud, Struski, Prade, Familiades, Eichner, Quelen, Bousquet, Mugneret, Talmant, Pages, Lefebvre, Penther, Lippert, Nadal, Taviaux, Poppe, Luquet, Baranger, Eclache, Radford, Barin, Mozziconacci et al.: Wide diversity of PAX5 alterations in B-ALL: a Groupe Francophone de Cytogenetique Hematologique study. ... in Blood 2010 (PubMed)
    Show all 2 references for ABIN969552

  7. Human Monoclonal PAX5 Primary Antibody for IHC, ELISA - ABIN1098104 : OBrien, Morin, Ouellette, Robichaud: The Pax-5 gene: a pluripotent regulator of B-cell differentiation and cancer disease. in Cancer research 2011 (PubMed)
    Show all 2 references for ABIN1098104

  8. Human Polyclonal PAX5 Primary Antibody for WB - ABIN374250 : Adams, Dörfler, Aguzzi, Kozmik, Urbánek, Maurer-Fogy, Busslinger: Pax-5 encodes the transcription factor BSAP and is expressed in B lymphocytes, the developing CNS, and adult testis. in Genes & development 1992 (PubMed)

  9. Chicken Polyclonal PAX5 Primary Antibody for IHC, WB - ABIN2775953 : Robichaud, Nardini, Laflamme, Cuperlovic-Culf, Ouellette: Human Pax-5 C-terminal isoforms possess distinct transactivation properties and are differentially modulated in normal and malignant B cells. in The Journal of biological chemistry 2004 (PubMed)

More Antibodies against PAX5 Interaction Partners

Human Paired Box 5 (PAX5) interaction partners

  1. PAX2 (show PAX2 Antibodies) and PAX5 are useful biomarker in the differential diagnosis of lung cancer

  2. Our findings suggest that this mutation in a single allele of the PAX5 gene is not sufficient to cause disease, and it is possible that other alleles are also involved in the onset of B-ALL.

  3. PAX5 methylated imprint margins may signify recurrence in head and neck squamous cell carcinoma

  4. Authors demonstrate leukemogenicity of PAX5-PML (show PML Antibodies) by introducing it into normal mouse pro-B cells; B-cell linker protein (Blnk (show BLNK Antibodies)) is repressed by PAX5-PML (show PML Antibodies) in leukemia cells; enforced expression of Blnk (show BLNK Antibodies) increases survival despite introduction of PAX5-PML (show PML Antibodies).

  5. PAX5 deletion is an independent risk factor for DFS (show FST Antibodies) in B-ALL children.

  6. Differential PAX5 levels promote malignant B-cell infiltration, progression and drug resistance, and predict a poor prognosis in mantle cell lymphoma patients independent (show CCND1 Antibodies) of CCND1.

  7. This is the first reported case of a novel complex variant translocation of t(11;14)(q13;q32) and t(9;14)(p13;q32)in PAX5-positive plasma cell myeloma.

  8. data suggested the differential regulation of hDAO expression by two promoters whose activities may be modulated by the binding of PAX2 (show PAX2 Antibodies) and PAX5

  9. Cells from PAX5 translocated patients show LCK (show LCK Antibodies) up-regulation and over-activation, as well as STAT5 (show STAT5A Antibodies) hyper-phosphorylation, compared to PAX5 wt and PAX5 deleted cases.

  10. Increased hypermethylation of PAX5 is associated with Triple negative breast cancer.

Xenopus laevis Paired Box 5 (PAX5) interaction partners

  1. Pax5 transcription factor cooperates in patterning the Xenopus brain.

Mouse (Murine) Paired Box 5 (PAX5) interaction partners

  1. Differential PAX5 levels promote malignant B-cell infiltration, progression and drug resistance, and predict a poor prognosis in mantle cell lymphoma independent of CCND1 (show CCND1 Antibodies).

  2. Spleen-specific isoform of Pax5 and Ataxin-7 (show ATXN7 Antibodies) can be considered as spleen-specific unique molecular markers for the evaluation of splenomegaly and lympho-proliferative disorders.

  3. Pax5 and Ebf1 (show EBF1 Antibodies) collaborate to modulate the transcriptional response to Notch (show NOTCH1 Antibodies) signaling, and their combined heterozygous loss allows for T-lineage conversion of B cell progenitors.

  4. a dramatic increase in the frequency of pro-B cell leukemia was observed in mice with combined heterozygous mutations in the Ebf1 (show EBF1 Antibodies) and Pax5 genes, revealing a synergistic effect of combined dose reduction of these proteins

  5. These results show that in contrast to simple Pax5 haploinsufficiency, multiple sequential alterations targeting lymphoid development are central to leukemogenesis and contribute to the arrest in lymphoid maturation characteristic of ALL.

  6. miR (show MLXIP Antibodies)-155 inhibits PU.1 expression, leading to Pax5 down-regulation and the initiation of the plasma cell differentiation pathway.

  7. restoring endogenous Pax5 expression in established B-ALL triggers immunophenotypic maturation and durable disease remission by engaging a transcriptional program reminiscent of normal B-cell differentiation

  8. Pax5 in GABAergic neurons is essential for normal ventricular development.

  9. results suggest that osteoblastic Pax5 would play a role in ovariectomy-induced bone loss through a mechanism relevant to the promotion of both osteoblastic bone formation and osteoclastic bone resorption in vivo

  10. Pax5 regulates Aicda (show AICDA Antibodies) transcription through its C-terminal-activation domain

Zebrafish Paired Box 5 (PAX5) interaction partners

  1. pax5 works in conjunction with fgf3 (show FGF3 Antibodies) and pax2a to establish and/or maintain the utricular macula and is essential for vestibular function.

PAX5 Antigen Profile

Protein Summary

This gene encodes a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. This gene encodes the B-cell lineage specific activator protein that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis and so the encoded protein may also play a role in neural development and spermatogenesis. This gene is located at 9p13, which is involved in t(9\;14)(p13\;q32) translocations recurring in small lymphocytic lymphomas of the plasmacytoid subtype, and in derived large-cell lymphomas. This translocation brings the potent E-mu enhancer of the IgH gene into close proximity of the PAX5 promoter, suggesting that the deregulation of transcription of this gene contributes to the pathogenesis of these lymphomas. Alternatively spliced transcript variants encoding different isoforms have been described but their biological validity has not been determined.

Gene names and symbols associated with anti-Paired Box 5 (PAX5) Antibodies

  • paired box 5 (PAX5) antibody
  • paired box 5 (pax5) antibody
  • paired box 5 (Pax5) antibody
  • paired box gene 5 (Pax5) antibody
  • paired box gene 5 (pax5) antibody
  • BSAP antibody
  • EBB-1 antibody
  • KLP antibody
  • noi antibody
  • Pax-5 antibody
  • pax2.1 antibody
  • pax2a antibody
  • PAX5 antibody
  • pax5-a antibody
  • paxzf-b antibody
  • Pax[Zf-b] antibody
  • RGD1565236 antibody

Protein level used designations for anti-Paired Box 5 (PAX5) Antibodies

paired box 5 , paired box gene 5 (B-cell lineage specific activator) , paired box protein Pax-5 , paired box protein Pax-5-like , B-cell lineage specific activator , paired box homeotic gene 5 , paired domain gene 5 , transcription factor PAX 5 , XPax-5 , B-cell-specific transcription factor , Pax5 variant 1 , Pax5 variant 2 , No isthmus protein

GENE ID SPECIES
716839 Macaca mulatta
747452 Pan troglodytes
100055252 Equus caballus
100389113 Callithrix jacchus
100457719 Pongo abelii
100481668 Ailuropoda melanoleuca
100586040 Nomascus leucogenys
5079 Homo sapiens
378499 Xenopus laevis
387330 Gallus gallus
612021 Canis lupus familiaris
500453 Rattus norvegicus
100520167 Sus scrofa
538371 Bos taurus
18507 Mus musculus
60636 Danio rerio
Selected quality suppliers for anti-PAX5 (PAX5) Antibodies
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