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Structural component of the gap junctions and the hemichannels.. Additionally we are shipping Pannexin 3 Proteins (4) and many more products for this protein.
Showing 10 out of 23 products:
Human Polyclonal PANX3 Primary Antibody for EIA, WB - ABIN953984
Iwamoto, Nakamura, Doyle, Ishikawa, de Vega, Fukumoto, Yamada: Pannexin 3 regulates intracellular ATP/cAMP levels and promotes chondrocyte differentiation. in The Journal of biological chemistry 2010
Show all 5 references for ABIN953984
Human Polyclonal PANX3 Primary Antibody for WB - ABIN2775572
Penuela, Bhalla, Gong, Cowan, Celetti, Cowan, Bai, Shao, Laird: Pannexin 1 and pannexin 3 are glycoproteins that exhibit many distinct characteristics from the connexin family of gap junction proteins. in Journal of cell science 2007
The results of this study do not support a major contribution of PANX1 (show PANX1 Antibodies)-3 to disease risk of schizophrenia according to DSM-5.
Case Report: osteosarcomatous transformation of axillary sweat gland neoplasm with high PANX3 expression.
Panx3 hemichannel is expressed in human odontoblast-like cells and mediates ATP release into the extracellular space.
Panx1 (show PANX1 Antibodies) and Panx3 are co-expressed in human skeletal muscle myoblasts and play a pivotal role in dictating the proliferation and differentiation.
Data suggest that both up-regulation and down-regulation of expression of pannexins (PANX1 (show PANX1 Antibodies), PANX2 (show PANX2 Antibodies), PANX3) are associated with disease onset and/or progression; examples include neoplasms, multiple sclerosis, migraine, and hypertension. [REVIEW]
The 70 kDa immunoreactive species of Panx3 highly regulated during keratinocyte differentiation was shown to most likely correspond to another Panx3 isoform.
Panx3 functions to switch the chondrocyte cell fate from proliferation to differentiation by regulating the intracellular ATP/cAMP levels
although Panx1 (show PANX1 Antibodies) and Panx3 share a common endoplasmic reticulum to Golgi secretory pathway to Cx43 (show GJA1 Antibodies), their ultimate cell surface residency appears to be independent of cell contacts and the need for intact microtubules
These studies show that Panx1 (show PANX1 Antibodies) and Panx3 have many characteristics that are distinct from Cx43 (show GJA1 Antibodies) and that these proteins probably play an important biological role as single membrane channels.
The study has identified several genetic loci that influence both body mass index and carcinogenesis and implicate Panx3 as a candidate gene that links these phenotypes through its effects on inflammation and lipid metabolism.
Our results clearly show that Panx3 ablation produces phenotypic effects in mouse femora and humeri, and support the premise that Panx3 has a role in regulating long bone growth and development.
Panx3 functions as an endoplasmic reticulum (ER) Ca(2 (show CA2 Antibodies)+) channel to promote differentiation, and it could rescue mineralization defects in Cx43 (show GJA1 Antibodies)(-/-) calvarial cells.
Mice lacking Panx3 are resistant to the development of osteoarthritis.
results provide evidence of the crucial roles of Panx3 in vertebrate skeletal development in vivo.
Panx3 is a new regulator that promotes the switch from proliferation to differentiation of osteoprogenitors via multiple Panx3 signaling pathways.
Panx3 may serve an important role in bone development, and is a novel target for Runx2 (show RUNX2 Antibodies)-dependent signaling.
Panx3 promotes osteoblast differentiation by functioning as an ER Ca(2 (show CA2 Antibodies)+) channel and a hemichannel, and by forming gap junctions.
Panx1 (show PANX1 Antibodies) and Panx3 are coexpressed in the mammalian epidermis, and the regulation of Panx1 (show PANX1 Antibodies) plays a key role in keratinocyte differentiation.
Structural component of the gap junctions and the hemichannels.
, pannexin 3
, gap junction protein pannexin 3