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anti-Paraoxonase 2 (PON2) Antibodies

PON2 encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. Additionally we are shipping PON2 Proteins (19) and PON2 Kits (18) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PON2 5445 Q15165
PON2 330260 Q62086
PON2 296851 Q6AXM8
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Top anti-PON2 Antibodies at antibodies-online.com

Showing 10 out of 105 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, FACS, IHC (p), WB Flow cytometric analysis of K562 cells using PON2 Antibody (N-term) Cat.-No AP53391PU-N (right histogram) compared to a negative control cell (left histogram). FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis. Immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue reacted with PON2 Antibody (N-term) followed which was peroxidase conjugated to the secondary antibody and followed by DAB staining. This data demonstrates the use of PON2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated WB Observed bind size: 39KD 100 μg Log in to see 4 to 6 Days
$240.00
Details
Mouse Rabbit Un-conjugated WB Lane 1: MarkerLane 2: 50 µg Mouse brain tissue lysate Primary antibody: 4 µg/mL Rabbit Anti-PON2 Polyclonal Antibody (ABIN398530) Lane 3: 50 µg Mouse brain tissue lysate Primary antibody: 2 µg/mL Rabbit Anti-PON2 Polyclonal Antibody (ABIN398530) Lane 4: 50 µg Mouse brain tissue lysate Primary antibody: 1 µg/mL Rabbit Anti-PON2 Polyclonal Antibody (ABIN398530) Secondary antibody: Goat Anti-Rabbit IgG (H&L) [HRP] Polyclonal Antibody (ABIN398323, 1: 10,000) 40 μg Log in to see 3 to 4 Days
$147.40
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated IF, IHC (p), WB PON2 Antibody (Center) (ABIN651946) western blot analysis in HepG2 cell line lysates (15 µg/lane). This demonstrates the PON2 antibody detected PON2 protein (arrow). PON2 Antibody (Center) (ABIN651946) western blot analysis in mouse heart tissue lysates (15 µg/lane). This demonstrates the PON2 antibody detected PON2 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB PON2 Antibody (N-term)  western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the PON2 antibody detected the PON2 protein (arrow). PON2 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PON2 Antibody (N-term) for immunohistochemistry.  Clinical relevance has not been evaluated. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB WB Image Sample (50 ug of whole cell lysate) A: mouse liver 10% SDS PAGE antibody diluted at 1:1000 WB Image Sample (30 ug of whole cell lysate) A: A431 , 10% SDS PAGE PON2 antibody antibody diluted at 1:1000 100 μL Log in to see 2 to 3 Days
$358.60
Details
Dog Goat Un-conjugated EIA, WB Antibody (0.2µg/ml) staining of HepG2 lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated EIA, IHC (p) 50 μg Log in to see 6 to 8 Days
$500.50
Details

PON2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Rat (Rattus) ,
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Top referenced anti-PON2 Antibodies

  1. Human Polyclonal PON2 Primary Antibody for EIA, FACS - ABIN954246 : Altenhöfer, Witte, Teiber, Wilgenbus, Pautz, Li, Daiber, Witan, Clement, Förstermann, Horke: One enzyme, two functions: PON2 prevents mitochondrial superoxide formation and apoptosis independent from its lactonase activity. in The Journal of biological chemistry 2010 (PubMed)
    Show all 4 references for ABIN954246

  2. Mouse (Murine) Polyclonal PON2 Primary Antibody for WB - ABIN1573944 : Devarajan, Bourquard, Hama, Navab, Grijalva, Morvardi, Clarke, Vergnes, Reue, Teiber, Reddy: Paraoxonase 2 deficiency alters mitochondrial function and exacerbates the development of atherosclerosis. in Antioxidants & redox signaling 2011 (PubMed)
    Show all 2 references for ABIN1573944

More Antibodies against PON2 Interaction Partners

Human Paraoxonase 2 (PON2) interaction partners

  1. PON2 SNPs rs12026 and rs7493 were associated with intracerebral hemorrhage. The C alleles of rs12026 and rs7493 contributed to a decreased risk of ICH (show COL4a2 Antibodies).

  2. Data indicate the relationship between ubiqutination of lysine (Lys (show LYZ Antibodies)) 168 and paraoxonase 2 (PON2) catalytic activity.

  3. Data suggest cigarette smoke leads to inhibition of hydrolytic activity of paraoxonase isoenzymes (PON1 (show PON1 Antibodies), PON2, PON3 (show PON3 Antibodies)) by modification of thiol groups, by interactions with free radicals/heavy metals, or by decreasing HDL (show HSD11B1 Antibodies) level in blood. [REVIEW]

  4. Haplotype containing two risk alleles of PON1 (show PON1 Antibodies) and PON2 genes was significantly associated with disease diabetes mellitus, type 2.

  5. D1-like receptors inhibit ROS (show ROS1 Antibodies) production by altering PON2 distribution in membrane microdomains in the short-term, and by increasing PON2 expression in the long-term.

  6. PON2 is a central regulator of host cell responses to Pseudomonas aeruginosa N-(3-oxo-dodecanoyl)-L-homoserine lactone

  7. PON2 levels reflect the cells' irradiation sensitivity.

  8. Newborns with PON2 148AG/GG genotype and exposed to high concentrations of MBP (show MBL2 Antibodies) and MEHP had higher risks of LBW and SBL

  9. A modest dose-dependent allele effect between the PON2 c.311C > G polymorphism, increased triglyceride concentrations and decreased LDL particle size distribution.

  10. Taken together, our data suggest a model by which DJ-1 (show PARK7 Antibodies) exerts its antioxidant activities, at least partly through regulation of PON2.

Mouse (Murine) Paraoxonase 2 (PON2) interaction partners

  1. PON2 plays an important role in innate immune defense against Pseudomonas aeruginosa infection.

  2. macrophage triglyceride accumulation upregulates PON2 expression via MEK (show MDK Antibodies)/ JNK/c-Jun pathway, and these effects could be related, at least in part, to cellular triglycerides-induced ROS (show ROS1 Antibodies) formation.

  3. These results suggest that PON2 is a novel major intracellular factor that protects CNS cells against oxidative stress and confers gender-dependent susceptibility to such stress

  4. Macrophage PON2 modulates mechanisms that link endoplasmic reticulum stress, mitochondrial dysfunction and the development of atherosclerosis.

  5. results demonstrate that PON2 plays an important role in hepatic insulin (show INS Antibodies) signalling and underscores the influence of macrophage-mediated inflammatory response on hepatic insulin (show INS Antibodies) sensitivity.

  6. Results illustrate that the antiatherogenic effects of PON2 are, in part, mediated by the role of PON2 in mitochondrial function.

  7. Under normal conditions macrophage endoplasmic reticulum stabilizes PON2 activity, and this effect could be attributed to ER proteins and redox status.

  8. PON2 proteins were present in the vast majority of tissues investigated. mRNA for these proteins was also expressed in most of these tissues suggesting local production and the ability to respond in situ to inflammatory stimuli.

  9. Pomegranite juice consumption antioxidative properties on mouse macrophages are mediated via PJ-induced stimulation of macrophage PON2 expression.

  10. analysis of macrophage cholesterol biosynthesis and decreased cellular paraoxonase 2 (PON2) expression in Delta6-desaturase knockout (6-DS KO) mice

Pig (Porcine) Paraoxonase 2 (PON2) interaction partners

  1. The expression of the PON2 gene was greater in Meishan pig than that in Yorkshire on gestational day 26 and 90.

Cow (Bovine) Paraoxonase 2 (PON2) interaction partners

  1. The aim of this study was to evaluate expression of the natural anti-oxidants paraoxonase (PON) 1 (show PON1 Antibodies), 2 and 3 in granulosa cells and PON1 (show PON1 Antibodies) activity in follicular fluid and plasma of dairy cows.

PON2 Antigen Profile

Protein Summary

This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described.

Gene names and symbols associated with anti-Paraoxonase 2 (PON2) Antibodies

  • paraoxonase 2 (PON2) antibody
  • paraoxonase 2 (LOC100218152) antibody
  • paraoxonase 2 (LOC100340152) antibody
  • Serum paraoxonase/arylesterase 2 (pon1) antibody
  • serum paraoxonase/arylesterase 2 (BDBG_00600) antibody
  • Serum paraoxonase/arylesterase 2 (pon2) antibody
  • paraoxonase 2 (Pon2) antibody
  • 6330405I24Rik antibody
  • AI481612 antibody
  • MGC53915 antibody
  • pon1 antibody
  • pon2 antibody

Protein level used designations for anti-Paraoxonase 2 (PON2) Antibodies

A-esterase 2 , Aromatic esterase 2 , PON 2 , Serum aryldialkylphosphatase 2 , Serum paraoxonase/arylesterase 2 , paraoxonase 2 , celiac disease 2 , serum paraoxonase/arylesterase 2-like , serum paraoxonase/arylesterase 2 , aromatic esterase 2 , paraoxonase nirs , serum aryldialkylphosphatase 2

GENE ID SPECIES
100303695 Meleagris gallopavo
463549 Pan troglodytes
100145861 Ovis aries
100218152 Taeniopygia guttata
100340152 Oryctolagus cuniculus
100407939 Callithrix jacchus
380341 Xenopus laevis
8507698 Ajellomyces dermatitidis SLH14081
100196477 Salmo salar
5445 Homo sapiens
330260 Mus musculus
296851 Rattus norvegicus
403855 Canis lupus familiaris
100142663 Sus scrofa
281417 Bos taurus
395830 Gallus gallus
Selected quality suppliers for anti-PON2 (PON2) Antibodies
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