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Patatin-Like phospholipase Domain Containing 8 Proteins (PNPLA8)

PNPLA8 encodes a member of the patatin-like phospholipase domain containing protein family. Additionally we are shipping Patatin-Like phospholipase Domain Containing 8 Antibodies (36) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PNPLA8 50640 Q9NP80
PNPLA8 67452 Q8K1N1
Rat PNPLA8 PNPLA8 314075  
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Top Patatin-Like phospholipase Domain Containing 8 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 59 to 64 Days
$8,623.45
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 59 to 64 Days
$6,052.17
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details

PNPLA8 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Patatin-Like phospholipase Domain Containing 8 (PNPLA8) Interaction Partners

Human Patatin-Like phospholipase Domain Containing 8 (PNPLA8) interaction partners

  1. iPLA2gamma plays an important role in in vivo Thromboxane A2 production accompanied by thrombus formation.

  2. iPLA2gamma plays a cardioprotective role during the acute stage of Chagas' disease.

  3. Thus, complement-mediated activation of iPLA(2)gamma is mediated via ERK (show EPHB2 Proteins) and p38 (show CRK Proteins) pathways, and phosphorylation of Ser (show SIGLEC1 Proteins)-511 and/or Ser (show SIGLEC1 Proteins)-515 plays a key role in the catalytic activity and signaling of iPLA(2)gamma.

  4. These results suggest distinct roles for iPLA2beta (show PLA2G6 Proteins) and iPLA2gamma in cellular homeostasis and signaling, a functional link between peroxisomal AA release and eicosanoid generation, and a potential contribution of iPLA2gamma to tumorigenesis.

  5. iPLA2 (show PLA2G6 Proteins) activation is not sufficient for SOCE activation. iPLA2 (show PLA2G6 Proteins) may regulate basal phosphoinositide metabolism

Mouse (Murine) Patatin-Like phospholipase Domain Containing 8 (PNPLA8) interaction partners

  1. UCP2 (show UCP2 Proteins), functional due to fatty acids released by redox-activated mt-iPLA2gamma, suppresses mitochondrial superoxide production by its uncoupling action.

  2. Mitochondrial dysfunction and reduced prostaglandin synthesis in skeletal muscle of Group VIB (show SEMA6B Proteins) Ca2 (show CA2 Proteins)+-independent phospholipase A2gamma-deficient mice

  3. iPLA(2)beta (show PLA2G6 Proteins) and iPLA(2 (show PLA2G6 Proteins))gamma are required for the adipogenic program that drives resting 3T3-L1 cells into adipocytes after hormone stimulation

  4. iPLA2 (show PLA2G6 Proteins) signaling plays an important role in glucose-stimulated insulin (show INS Proteins) secretion under physiological conditions

  5. iPLA(2 (show PLA2G6 Proteins))gamma is essential for maintaining efficient bioenergetic mitochondrial function through tailoring mitochondrial membrane lipid metabolism and composition

  6. the obligatory role of iPLA(2 (show PLA2G6 Proteins))gamma in neuronal mitochondrial lipid metabolism and membrane structure demonstrating that iPLA(2 (show PLA2G6 Proteins))gamma loss of function results in a mitochondrial neurodegenerative disorder

Patatin-Like phospholipase Domain Containing 8 (PNPLA8) Protein Profile

Protein Summary

This gene encodes a member of the patatin-like phospholipase domain containing protein family. Members of this family are phospholipases which catalyze the cleavage of fatty acids from membrane phospholipids. The product of this gene is a calcium-independent phospholipase. A pseudogene of this gene is located on the X chromosome. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with PNPLA8

  • patatin-like phospholipase domain containing 8 (PNPLA8)
  • patatin-like phospholipase domain containing 8 (Pnpla8)
  • 1200006O19Rik protein
  • AI467579 protein
  • iPLA2 protein
  • Ipla2(gamma) protein
  • IPLA2-2 protein
  • IPLA2G protein
  • iPLA2gamma protein
  • RGD1311444 protein

Protein level used designations for PNPLA8

PNPLA-gamma , calcium-independent phospholipase A2-gamma , iPLA2 gamma , iPLA2-gamma , intracellular membrane-associated calcium-independent phospholipase A2 gamma , membrane-associated calcium-independent phospholipase A2 gamma , patatin-like phospholipase domain-containing protein 8 , group VIB calcium-independent phospholipase A2

GENE ID SPECIES
50640 Homo sapiens
67452 Mus musculus
314075 Rattus norvegicus
100328577 Oryctolagus cuniculus
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