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This is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs), RF1 and RF1/RF2, as well as retroviral-like slippage and pseudoknot elements, which can induce a -1 nucleotide frame-shift. Additionally we are shipping Paternally Expressed 10 Kits (4) and Paternally Expressed 10 Proteins (4) and many more products for this protein.
Showing 10 out of 94 products:
Human Monoclonal PEG10 Primary Antibody for IHC, ELISA - ABIN969349
Jie, Lang, Jian, Chaoqun, Dehua, Yi, Yanping, Luokun, Qiuping, Hui, Feili, Boquan, Youxin, Jinquan: Androgen activates PEG10 to promote carcinogenesis in hepatic cancer cells. in Oncogene 2007
Show all 3 references for ABIN969349
Human Monoclonal PEG10 Primary Antibody for ICC, IHC - ABIN969348
Kochetov, Ahmad, Ivanisenko, Volkova, Kolchanov, Sarai: uORFs, reinitiation and alternative translation start sites in human mRNAs. in FEBS letters 2008
Show all 3 references for ABIN969348
Human Polyclonal PEG10 Primary Antibody for EIA, FACS - ABIN954082
Tsuji, Yasui, Gen, Endo, Dohi, Zen, Mitsuyoshi, Minami, Itoh, Taniwaki, Tanaka, Arii, Okanoue, Yoshikawa: PEG10 is a probable target for the amplification at 7q21 detected in hepatocellular carcinoma. in Cancer genetics and cytogenetics 2010
Show all 3 references for ABIN954082
Human Monoclonal PEG10 Primary Antibody for IF, WB - ABIN2869375
Wang, Xiao, Hu, Chen, Liu, Hu: PEG10 directly regulated by E2Fs might have a role in the development of hepatocellular carcinoma. in FEBS letters 2008
Show all 2 references for ABIN2869375
Human Polyclonal PEG10 Primary Antibody for FACS, WB - ABIN656590
Lux, Beil, Majety, Barron, Gallione, Kuhn, Berg, Kioschis, Marchuk, Hafner: Human retroviral gag- and gag-pol-like proteins interact with the transforming growth factor-beta receptor activin receptor-like kinase 1. in The Journal of biological chemistry 2005
Show all 2 references for ABIN656590
important role in trophoblast proliferation and promotes trophoblast invasion through TIMP-1 (show TIMP1 Antibodies)
Results revealed that PEG10 high expression was closely associated with the TNM (show ODZ1 Antibodies) classification in lung cancer and is a critical indicator for poor prognosis. Also, It promotes significantly proliferation, migration and invasion of A549 lung cancer cells.
The downregulated expression of the imprinted gene PEG10 may be an important reason for the occurrence of preeclampsia.
elevated expression of PEG10 is likely to be involved in the pathophysiology of preeclampsia
promotes migration of Burkitt's lymphoma cells via upregulation of matrix metalloproteinase-2 (show MMP2 Antibodies) and -9
Overexpression of PEG10 and TSG101 (show TSG101 Antibodies) was detected in gallbladder adenocarcinoma.
PEG10 imprinting is lost in a majority of hepatocellular carcinomas and no correlation exists between the imprinting status of PEG10 and its expression in HCC (show FAM126A Antibodies) tissues.
the mRNA expression level of PEG10 were significantly up-regulated in tumorous liver tissues compared with corresponding nontumorous counterparts.
In third trimester PEG10 was downregulated in fetal samples group
PEG10 gene is imprinted, with preferential expression from the paternal allele.
polymorphisms in PEG10 and PPP1R9A (show PPP1R9A Antibodies) were associated with fat deposition and carcass traits
The imprinting status of PEG10 is conserved in swine as paternal expression was demonstrated by quantitative allelic sequencing of reciprocal crosses in fetal tissues of whole brain, carcass, liver and placentae.
The expression patterns of PLAGL1 (show PLAGL1 Antibodies) and PEG10 genes in two breeds of swine are reported.
the abnormal DNA methylation (show HELLS Antibodies) epigenetic reprogramming of imprinting PEG10 gene in placenta may be one of the main causes of the abnormal development and death of the transgenic cloned cattle.
Loss of DNA methylation (show HELLS Antibodies) at the Peg10 imprinted gDMD associated with decreased embryonic viability and decreased labyrinthine volume.
Knockdown of Syncytin-A (show ERVW-1 Antibodies) demonstrated a functional regulation of cell-cell fusion, where knockdown of Peg10 showed no involvement in cell fusion
Programmed -1 ribosomal frameshifting in mouse and human Peg10 genes.
Peg10 gene is imprinted, with preferential expression from the paternal allele, and its deletion results in early embryonic lethality.
Results indicate that the induction of the imprinted gene paternally expressed 10 (PEG10) may play an important role during liver regeneration or carcinogenesis of the hepatocyte.
These findings strongly indicate that peg10 plays a crucial role at the immediate early (show JUN Antibodies) stage of adipocyte differentiation.
the ORF1 (show MED14 Antibodies)-2 protein of PEG10, synthesized utilizing the most efficient -1 frameshift mechanism yet documented in vivo, will have an essential function that is intrinsic to the importance of PEG10 in mammals
This is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs), RF1 and RF1/RF2, as well as retroviral-like slippage and pseudoknot elements, which can induce a -1 nucleotide frame-shift. ORF1 encodes a shorter isoform with a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons. The longer isoform is the result of -1 translational frame-shifting leading to translation of a gag/pol-like protein combining RF1 and RF2. It contains the active-site consensus sequence of the protease domain of pol proteins. Additional isoforms resulting from alternatively spliced transcript variants, as well as from use of upstream non-AUG (CUG) start codon, have been reported for this gene. Increased expression of this gene is associated with hepatocellular carcinomas.
paternally expressed 10
, MEF3 like 1
, MEF3-like protein 1
, embryonal carcinoma differentiation regulated
, embryonal carcinoma differentiation-regulated protein
, mammalian retrotransposon-derived protein 2
, myelin expression factor 3-like protein 1
, paternally expressed gene 10 protein
, retrotransposon gag domain containing 3
, retrotransposon gag domain-containing protein 3
, retrotransposon-derived gag-like polyprotein
, retrotransposon-derived protein PEG10
, ty3/Gypsy-like protein
, MyEF-3 like
, embryonal carcinoma differentiation regulated protein
, myelin expression factor 3