anti-Paternally Expressed 3 (PEG3) Antibodies

In human, ZIM2 and PEG3 are treated as two distinct genes though they share multiple 5' exons and a common promoter and both genes are paternally expressed (PMID:15203203). Additionally we are shipping and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PEG3 5178 Q9GZU2
PEG3 18616 Q3URU2
PEG3 246361  
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Top anti-PEG3 Antibodies at antibodies-online.com

Showing 10 out of 31 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-PEG3 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: A204 cell lysate WB Suggested Anti-PEG3  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control: A204 cell lysate  PEG3 is strongly supported by BioGPS gene expression data to be expressed in Human A204 cells 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p) Formalin-fixed and paraffin embedded rat brain tissue labeled with Anti-PEG3 Polyclonal Antibody, Unconjugated (ABIN735653) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$307.45
Details
Human Mouse Un-conjugated WB 100 μL Log in to see 7 to 9 Days
$493.17
Details
Human Mouse Un-conjugated IHC (p), WB 100 μL Log in to see 7 to 9 Days
$493.17
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 16 Days
$175.80
Details
Bat Rabbit Un-conjugated IHC (p), WB Human Brain, Cerebellum (formalin-fixed, paraffin-embedded) stained with PEG3 antibody ABIN214135 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 7 to 9 Days
$676.50
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Mouse Un-conjugated IHC, WB Immunohistochemistry: PEG3 Antibody (1E10) [NBP2-46379] - Analysis of Carcinoma of Human thyroid tissue. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min) Immunohistochemistry: PEG3 Antibody (1E10) [NBP2-46379] - Analysis of Human colon tissue. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min) 0.1 mL Log in to see 8 to 11 Days
$447.56
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 14 to 21 Days
$417.45
Details
Human Rabbit Alexa Fluor 488 IF (p)   100 μL Log in to see 14 to 21 Days
$417.45
Details

PEG3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-PEG3 Antibodies

  1. Human Polyclonal PEG3 Primary Antibody for IF (p), IHC (p) - ABIN735653 : Ge, Liang, Luo, Wei, Han, Schatten, Sun, Zhang: Diabetic uterus environment may play a key role in alterations of DNA methylation of several imprinted genes at mid-gestation in mice. in Reproductive biology and endocrinology : RB&E 2014 (PubMed)
    Show all 2 references for 735653

  2. Cow (Bovine) Polyclonal PEG3 Primary Antibody for WB - ABIN2780754 : Dowdy, Gostout, Shridhar, Wu, Smith, Podratz, Jiang: Biallelic methylation and silencing of paternally expressed gene 3 (PEG3) in gynecologic cancer cell lines. in Gynecologic oncology 2005 (PubMed)

More Antibodies against PEG3 Interaction Partners

Pig (Porcine) Paternally Expressed 3 (PEG3) interaction partners

  1. Porcine skeletal muscle-derived PW1(pos)/Pax7 (show PAX7 Antibodies)(neg (show TMEM131 Antibodies)) interstitial cells are a source of stem/progenitor cells.

  2. The PEG3 gene expression was not affected by day of pregnancy or breed.

  3. For PEG3, pigs expressed the paternal allele in skeletal muscle, liver, spleen, kidney, and uterus, but biallele in heart, lung, fat, stomach, small intestine, and ovary.

Human Paternally Expressed 3 (PEG3) interaction partners

  1. Peg3 transcriptionally modulates BECN1 (show BECN1 Antibodies) activity.

  2. Data indicate that a set of cis (show CISH Antibodies)-regulatory motifs and corresponding trans factors that may be critical for the transcriptional regulation of the Peg3 (Paternally Expressed Gene 3) domain.

  3. In the current study, the authors have identified three alternative promoters for mouse Peg3 and one alternative promoter for human PEG3.

  4. A resident population of resident smooth muscle progenitor cells expressing PW1 was identified in pulmonary hypertension-associated vascular remodeling.

  5. PW1/Peg3 function is essential for conferring proper mesoangioblast competence and it's level in human mesoangioblasts may serve as a biomarker to identify donor populations for therapeutic application in muscular dystrophies.

  6. The PEG3-SCAN domain appears to constitute an assembly block, enabling PEG3 homo- or heterodimerization to control gene expression in a combinatorial fashion.

  7. Genetic translocations involving PEG3 gene is associated with mesenchymal hamartoma of the liver.

  8. we have unveiled a mechanism for a secreted proteoglycan (show Vcan Antibodies) in inducing Peg3, a master regulator of macroautophagy in endothelial cells

  9. Results show that a five percent increase in DNA methylation (show HELLS Antibodies) of PEG3 is associated with a 1.6-fold increase invasive cervical cancer (ICC) risk.

  10. None of the folate cycle genotypes in the mother or infant were related to the methylation of IGF2, PEG3, or LINE-1.

Cow (Bovine) Paternally Expressed 3 (PEG3) interaction partners

  1. the expression of PEG3 domain genes within the maternal placenta is not significantly affected by the MIMT1Del mutation and alterations in PEG3 domain gene expression on the fetal side

  2. Data show that a 110 kb microdeletion in the maternally imprinted PEG3 domain that results in a loss of paternal MIMT1 expression and causes late term abortion and stillbirth.

  3. Peg3 was seriously demethylated or showed aberrant methylation patterns in four aborted clones.

  4. PEG3 imprinted domain of humans, cows, and mice contains differing numbers of differentially methylated regions (DMR (show WDR20 Antibodies)), but the PEG3-CpG island is the only DMR (show WDR20 Antibodies) that is conserved among these three species.

Mouse (Murine) Paternally Expressed 3 (PEG3) interaction partners

  1. Strand-specific CpG hemimethylation, a novel epigenetic modification functional for genomic imprinting, has been demonstrated for Peg3 gene.

  2. Data show that complete removal of paternally expressed gene 3 (PEG3) resulted in up-regulation of male-specific lethal 1 (Msl1 (show OPRK1 Antibodies)) and male-specific lethal 3 (Msl3 (show MSL3 Antibodies)).

  3. orientation of the Peg3-ICR may play no role in its allele-specific DNA methylation (show HELLS Antibodies)

  4. The results indicate that PW1 is a co-regulator of the beta cell cycle and can thus be considered a novel therapeutic target in diabetes.

  5. This study demonstrated the existence of a novel population of resident adult cardiac stem cells expressing PW1(+) and their involvement in fibrotic remodeling after MI.

  6. promoters of Peg3 derive sexually biased and tissue-specific expression patterns

  7. Our study also identified the imprinting control region (ICR) of H19 (show NCKAP1 Antibodies) as a genomic target. According to the results, PEG3 binds to a specific sequence motif located between the 3(rd) and 4(th) CTCF (show CTCF Antibodies) binding sites of the H19 (show NCKAP1 Antibodies)-ICR. PEG3 also binds to the active maternal allele of the H19 (show NCKAP1 Antibodies)-ICR.

  8. These results support a general role for Pw1/Peg3 in the regulation of body growth but not maternal care and lactation.

  9. Data indicate that a set of cis (show CISH Antibodies)-regulatory motifs and corresponding trans factors that may be critical for the transcriptional regulation of the Peg3 (Paternally Expressed Gene 3) domain.

  10. Data show that bisperoxovanadium (BpV) treatment induces specific epigenetic modifications at the promoter regions of genes associated with stem cell fate, including Sca-1 (show Ly6a Antibodies) and Pw1.

PEG3 Antigen Profile

Protein Summary

In human, ZIM2 and PEG3 are treated as two distinct genes though they share multiple 5' exons and a common promoter and both genes are paternally expressed (PMID:15203203). Alternative splicing events connect their shared 5' exons either with the remaining 4 exons unique to ZIM2, or with the remaining 2 exons unique to PEG3. In contrast, in other mammals ZIM2 does not undergo imprinting and, in mouse, cow, and likely other mammals as well, the ZIM2 and PEG3 genes do not share exons. Human PEG3 protein belongs to the Kruppel C2H2-type zinc finger protein family. PEG3 may play a role in cell proliferation and p53-mediated apoptosis. PEG3 has also shown tumor suppressor activity and tumorigenesis in glioma and ovarian cells. Alternative splicing of this PEG3 gene results in multiple transcript variants encoding distinct isoforms.

Gene names and symbols associated with PEG3

  • paternally expressed 3 (PEG3) antibody
  • paternally expressed 3 (Peg3) antibody
  • AL022617 antibody
  • ASF-1 antibody
  • End4 antibody
  • Gcap4 antibody
  • mKIAA0287 antibody
  • PEG3 antibody
  • Pw1 antibody
  • Zfp102 antibody
  • ZKSCAN22 antibody
  • ZNF904 antibody
  • ZSCAN24 antibody

Protein level used designations for PEG3

paternally expressed 3 , paternally-expressed gene 3 protein-like , Kruppel-type zinc finger protein , paternally-expressed gene 3 protein , zinc finger and SCAN domain-containing protein 24 , paternally expressed gene 3 , zinc-finger protein , granule cell antiserum positive 4

GENE ID SPECIES
707825 Macaca mulatta
100233196 Sus scrofa
100448879 Pongo abelii
100505405 Ovis aries
100510800 Felis catus
5178 Homo sapiens
476371 Canis lupus familiaris
100522552 Sus scrofa
444864 Bos taurus
18616 Mus musculus
469030 Pan troglodytes
246361 Rattus norvegicus
Selected quality suppliers for anti-PEG3 (PEG3) Antibodies
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