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Drosophila peroxidasin is an extracellular matrix-associated peroxidase (Horikoshi et al., 1999 [PubMed 10441517]). Additionally we are shipping PXDN Kits (15) and PXDN Proteins (9) and many more products for this protein.
Showing 10 out of 19 products:
VPO1 plays a critical role in asymmetric dimethylarginine production via H2O2-VPO1-hypochlorous acid pathways, which may contribute to endothelial dysfunction in hypertension.
PC processing of Pxdn is a key regulatory step that contributes to its function and, therefore, supports BM integrity and homeostasis.
PXDN expression is significantly upregulated in human masticatory mucosa during wound healing
Novel mutations in PXDN cause microphthalmia and anterior segment dysgenesis
Despite sequence homology at the active site and biophysical properties similar to human peroxidases, the catalytic efficiency of bromide oxidation (kcat/KM(app (show APP Antibodies))) of full-length hsPxd01 is rather low but increased upon truncation.
MiR (show MLXIP Antibodies)-4782-3p inhibited cell proliferation in NSCLC by targeting USP14, ZEB2 (show ZEB2 Antibodies) and XIAP (show XIAP Antibodies).
studies demonstrate the enzymatic properties and substrate specificity of VPO1 are similar to MPO (show MPO Antibodies); however, significantly lower catalytic rate constants of VPO1 relative to MPO (show MPO Antibodies) suggest the possibility of other physiologic roles for this peroxidase
VPO1 is likely to participate in host defense, with bactericidal activity mediated through the generation of HOCl.
Results from this study indicate that the 2p25.3 duplication disrupting PXDN and MYT1L (show MYT1L Antibodies) is a potential autism-causing variant in the pedigree reported here and should receive further consideration as a candidate for autism
Vascular peroxidase-1 is rapidly secreted, circulates in plasma, and supports dityrosine cross-linking reactions.
Cdkn1b (show CDKN1B Antibodies) exert its effects via the inhibition of proliferation and is mediated by miR (show MLXIP Antibodies)-24 and targeted by the transcription factors FOXO4 (show FOXO4 Antibodies) and AP4 (show REPIN1 Antibodies) in the peroxidasin (Pxdn) mutation-induced eye disorders, such as glaucoma.
Drosophila peroxidasin is an extracellular matrix-associated peroxidase (Horikoshi et al., 1999
melanoma-associated antigen MG50
, p53-responsive gene 2 protein
, peroxidasin homolog
, vascular peroxidase 1