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May play a role in placental development (By similarity).. Additionally we are shipping Placenta-Specific 1 Antibodies (22) and Placenta-Specific 1 Kits (6) and many more products for this protein.
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PLAC1/CP1 provides a marker for identifying gastric cancers with poor prognosis, and suggest that PLAC1/CP1 may provide a useful target for immunotherapy.
Data suggests that PLAC1 plays an important role in human placental trophoblast invasion and migration.
This data suggests that the Epstein-Barr virus-induced PLAC1 is a member of the cancer/testis group of tumor antigens.
PLAC1/CP1 antigen is a possible prognostic marker of colorectal carcinoma, and PLAC1/CP1 p41 (show EPB41 Proteins)-50 and PLAC1/CP1 p69 (show ICA1 Proteins)-77 are novel HLA-A*0201-restricted CD8 (show CD8A Proteins)+ T cell epitopes
NCOA3 (show NCOA3 Proteins) is a selective co-activator of estrogen receptor alpha (show ESR1 Proteins)-mediated transactivation of PLAC1.
we identified a novel specific antitrophoblast antibody, anti-PLAC1, in infertile women with repeated unexplained implantation failure. PLAC1 shows placenta-specific expression and is localized primarily in the syncytiotrophoblast.
A novel HLA-A2-restricted cytotoxic T lymphocyte epitope from cancer-testis antigen PLAC1 has been identified in breast cancer.
RXRalpha (show RXRA Proteins) and LXR (show NR1H3 Proteins) activate two promoters in placenta- and tumor-specific expression of PLAC1.
The expression of PLAC1/CP1 genes correlates with various clinical and pathologic parameters in primary colorectal carcinoma.
A potential role for PLAC1 as a biomarker predictive of specific pregnancy complications, such as preeclampsia.
Our findings suggest that Plac1 is involved in trophoblast cell proliferation, differentiation, and migration
Plac1 (placenta-specific 1) is widely expressed during fetal development and is associated with a lethal form of hydrocephalus.
Plac1 is a paternally imprinted, X-linked gene essential for normal placental and embryonic development.
May play a role in placental development (By similarity).
, placenta-specific protein 1
, cancer/testis antigen 92
, ectoplacental cone, invasive trophoblast giant cells, extraembryonic ectoderm and chorion sequence 26