anti-Platelet Endothelial Aggregation Receptor 1 (PEAR1) Antibodies

PEAR1 is a platelet receptor that signals upon the formation of platelet-platelet contacts independent of platelet activation and secondary to platelet aggregation (Nanda et al., 2005 [PubMed 15851471]).[supplied by OMIM, Mar 2008].. Additionally we are shipping PEAR1 Proteins (7) and PEAR1 Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PEAR1 375033 Q5VY43
PEAR1 73182 Q8VIK5
PEAR1 295293  
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Top anti-PEAR1 Antibodies at antibodies-online.com

Showing 10 out of 52 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue reacted with PEAR1 Antibody (C-term) followed which was peroxidase conjugated to the secondary antibody and followed by  DAB staining. This data demonstrates the use of the PEAR1 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. Western blot analysis of PEAR1 Antibody (C-term) in MDA-MB435 cell line lysates (35ug/lane). This demonstrates the PEAR1 antibody detected the PEAR1 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Goat Un-conjugated FACS, WB Detection of PEAR1 in Human CD41+ Platelets by Flow Cytometry. Human CD41+ platelets were stained with Human PEAR1 Antigen Affinity-purified Polyclonal Antibody. Detection of PEAR1 in Human CD41+ Platelets by Flow Cytometry. Human CD41+ platelets were stained with Human PEAR1 Antigen Affinity-purified Polyclonal Antibody. 100 μg Log in to see 8 to 9 Days
$372.75
Details
Human Rabbit Un-conjugated IHC (p), WB PEAR1 antibody (C-term) (ABIN654292) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB   0.1 mg Log in to see 12 to 15 Days
$375.38
Details
Human Mouse PE FACS Detection of PEAR1 in Human Blood Platelets by Flow Cytometry. Human peripheral blood platelets were stained with anti-human Integrin alpha 2b/CD41 FITC-conjugated antibody and either (A) Mouse Anti-Human PEAR1 PE-conjugated Monoclonal Antibody. 100 Tests Log in to see 8 to 9 Days
$315.00
Details
Human Mouse Alexa Fluor 488 FACS Detection of PEAR1 in Human Blood Platelets by Flow Cytometry. Human peripheral blood platelets were stained with Mouse Anti-Human Integrin alpha 2b/CD41 APC-conjugated Monoclonal Antibody. Detection of PEAR1 in Human Blood Platelets by Flow Cytometry. Human peripheral blood platelets were stained with Mouse Anti-Human Integrin alpha 2b/CD41 APC-conjugated Monoclonal Antibody. 100 Tests Log in to see 8 to 9 Days
$325.50
Details
Human Mouse Allophycocyanin FACS Detection of PEAR1 in Human Blood Platelets by Flow Cytometry. Human peripheral blood platelets were stained with anti-human Integrin alpha 2b/CD41 FITC-conjugated antibody and either (A) Mouse Anti-Human PEAR1 APC-conjugated Monoclonal Antibody. 100 Tests Log in to see 8 to 9 Days
$351.75
Details
Human Mouse Un-conjugated FACS, WB Detection of PEAR1 in Human Peripheral Blood Platelets by Flow Cytometry Human peripheral blood platelets were stained with Mouse Anti-Human PEAR1 Monoclonal Antibody. Detection of PEAR1 in Human Peripheral Blood Platelets by Flow Cytometry Human peripheral blood platelets were stained with Mouse Anti-Human PEAR1 Monoclonal Antibody. 100 μg Log in to see 8 to 9 Days
$262.50
Details
Mouse Sheep Un-conjugated FACS, WB Detection of PEAR1 in bEnd.3 Mouse Cell Line by Flow Cytometry. bEnd.3 mouse endo-thelioma cell line was stained with Sheep Anti-Mouse PEAR1 Antigen Affinity-purified Polyclonal Antibody. Detection of Mouse PEAR1 by Western Blot. Western blot shows lysates of mouse spleen tissue and mouse platelets. PVDF membrane was probed with 1 ug/mL of Sheep Anti-Mouse PEAR1 Antigen Affinity-purified Polyclonal Antibody. This experiment was conducted under reducing conditions. 100 μg Log in to see 8 to 9 Days
$372.75
Details
Human Mouse APC FACS   100 Tests Log in to see 7 to 9 Days
$1,079.83
Details

PEAR1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Mouse (Murine)
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Rat (Rattus)


Top referenced anti-PEAR1 Antibodies

  1. Human Polyclonal PEAR1 Primary Antibody for EIA, IHC (p) - ABIN954080 : Johnson, Yanek, Chen, Faraday, Larson, Tofler, Lin, Kraja, Province, Yang, Becker, ODonnell, Becker: Genome-wide meta-analyses identifies seven loci associated with platelet aggregation in response to agonists. in Nature genetics 2010 (PubMed)
    Show all 4 references for 954080

  2. Human Polyclonal PEAR1 Primary Antibody for FACS, WB - ABIN4899612 : Faraday, Yanek, Yang, Mathias, Herrera-Galeano, Suktitipat, Qayyum, Johnson, Chen, Tofler, Ruczinski, Friedman, Gylfason, Thorsteinsdottir, Bray, ODonnell, Becker, Becker: Identification of a specific intronic PEAR1 gene variant associated with greater platelet aggregability and protein expression. in Blood 2011 (PubMed)
    Show all 2 references for 4899612

More Antibodies against PEAR1 Interaction Partners

Human Platelet Endothelial Aggregation Receptor 1 (PEAR1) interaction partners

  1. DNA methylation (show HELLS Antibodies) at 4 different loci of PEAR1 during in vitro megakaryopoiesis, was studied.

  2. In a White population, we could not replicate previous reports from experimental studies or obtained in patients suggesting that PEAR1 might be a susceptibility gene for cardiovascular complications

  3. PEAR1 genetic variations were strongly associated with platelet reactivity in a Chinese patient population with coronary heart disease undergoing dual antiplatelet therapy with aspirin and clopidogrel.

  4. A considerable portion of Chinese ischemic stroke patients are insensitive to aspirin treatment, which may be correlated with the MDR1 (show TBC1D9 Antibodies) C3435T, TBXA2R (show TBXA2R Antibodies) (rs1131882), and PLA2G7 (show Lp-PLA2 Antibodies) (rs1051931-rs7756935) polymorphisms.

  5. Platelet endothelial aggregation receptor-1: a novel modifier of neoangiogenesis.

  6. Results suggest that genetic variation of PEAR1 is a significant determinant of endothelial function through pathways implicated in cardiovascular disease.

  7. FcepsilonRI (show FCER1G Antibodies) alpha-chain (show FCGRT Antibodies) is an activating platelet endothelium aggregation receptor 1 (PEAR1) ligand.

  8. genetic variability of GAS6 (show GAS6 Antibodies) and PEAR1 genes may be associated with platelet hyperaggregability

  9. A common genetic variant in PEAR1 (rs12041331) reproducibly influenced platelet aggregation in aspirin-treated patients with coronary artery disease.

  10. study suggests that PEAR1 is not a hypertension susceptibility gene in humans.

Mouse (Murine) Platelet Endothelial Aggregation Receptor 1 (PEAR1) interaction partners

  1. Platelet endothelial aggregation receptor-1: a novel modifier of neoangiogenesis.

  2. Jedi-1 signals through recruitment of GULP (show GULP1 Antibodies), which promotes phagocytosis through a noncanonical phosphoclathrin-dependent mechanism.

  3. These results indicated that both Jedi-1 and MEGF10 (show MEGF10 Antibodies) can mediate phagocytosis independently through the recruitment of Syk (show SYK Antibodies).

  4. Jedi is involved in the fine regulation of the early stages of hematopoietic differentiation, presumably through the Notch (show NOTCH1 Antibodies) signaling pathway.

  5. a cellular and molecular mechanism by which neuronal corpses are culled during dorsal root ganglia development involves Jedi protein

PEAR1 Antigen Profile

Protein Summary

PEAR1 is a platelet receptor that signals upon the formation of platelet-platelet contacts independent of platelet activation and secondary to platelet aggregation (Nanda et al., 2005

Gene names and symbols associated with PEAR1

  • platelet endothelial aggregation receptor 1 (PEAR1) antibody
  • platelet endothelial aggregation receptor 1 (pear1) antibody
  • platelet endothelial aggregation receptor 1 (LOC100338327) antibody
  • platelet endothelial aggregation receptor 1 (Pear1) antibody
  • 3110045G13Rik antibody
  • JEDI antibody
  • Jedi-1 antibody
  • Megf12 antibody
  • RGD1305653 antibody

Protein level used designations for PEAR1

platelet endothelial aggregation receptor 1 , multiple EGF-like-domains 12 , platelet endothelial aggregation receptor 1-like , hPEAR1 , multiple EGF-like domains protein 12 , multiple epidermal growth factor-like domains protein 12 , Jedi , jagged and Delta protein , mPEAR1 , protein Jedi

GENE ID SPECIES
457409 Pan troglodytes
490403 Canis lupus familiaris
571812 Danio rerio
718698 Macaca mulatta
787112 Bos taurus
100023818 Monodelphis domestica
100064623 Equus caballus
100338327 Oryctolagus cuniculus
100451525 Pongo abelii
100586891 Nomascus leucogenys
375033 Homo sapiens
73182 Mus musculus
295293 Rattus norvegicus
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