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PEAR1 is a platelet receptor that signals upon the formation of platelet-platelet contacts independent of platelet activation and secondary to platelet aggregation (Nanda et al., 2005 [PubMed 15851471]).[supplied by OMIM, Mar 2008].. Additionally we are shipping PEAR1 Proteins (7) and PEAR1 Kits (3) and many more products for this protein.
Showing 10 out of 52 products:
Human Polyclonal PEAR1 Primary Antibody for EIA, IHC (p) - ABIN954080
Johnson, Yanek, Chen, Faraday, Larson, Tofler, Lin, Kraja, Province, Yang, Becker, ODonnell, Becker: Genome-wide meta-analyses identifies seven loci associated with platelet aggregation in response to agonists. in Nature genetics 2010
Show all 4 references for 954080
Human Polyclonal PEAR1 Primary Antibody for FACS, WB - ABIN4899612
Faraday, Yanek, Yang, Mathias, Herrera-Galeano, Suktitipat, Qayyum, Johnson, Chen, Tofler, Ruczinski, Friedman, Gylfason, Thorsteinsdottir, Bray, ODonnell, Becker, Becker: Identification of a specific intronic PEAR1 gene variant associated with greater platelet aggregability and protein expression. in Blood 2011
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DNA methylation (show HELLS Antibodies) at 4 different loci of PEAR1 during in vitro megakaryopoiesis, was studied.
In a White population, we could not replicate previous reports from experimental studies or obtained in patients suggesting that PEAR1 might be a susceptibility gene for cardiovascular complications
PEAR1 genetic variations were strongly associated with platelet reactivity in a Chinese patient population with coronary heart disease undergoing dual antiplatelet therapy with aspirin and clopidogrel.
A considerable portion of Chinese ischemic stroke patients are insensitive to aspirin treatment, which may be correlated with the MDR1 (show TBC1D9 Antibodies) C3435T, TBXA2R (show TBXA2R Antibodies) (rs1131882), and PLA2G7 (show Lp-PLA2 Antibodies) (rs1051931-rs7756935) polymorphisms.
Platelet endothelial aggregation receptor-1: a novel modifier of neoangiogenesis.
Results suggest that genetic variation of PEAR1 is a significant determinant of endothelial function through pathways implicated in cardiovascular disease.
FcepsilonRI (show FCER1G Antibodies) alpha-chain (show FCGRT Antibodies) is an activating platelet endothelium aggregation receptor 1 (PEAR1) ligand.
genetic variability of GAS6 (show GAS6 Antibodies) and PEAR1 genes may be associated with platelet hyperaggregability
A common genetic variant in PEAR1 (rs12041331) reproducibly influenced platelet aggregation in aspirin-treated patients with coronary artery disease.
study suggests that PEAR1 is not a hypertension susceptibility gene in humans.
Jedi-1 signals through recruitment of GULP (show GULP1 Antibodies), which promotes phagocytosis through a noncanonical phosphoclathrin-dependent mechanism.
These results indicated that both Jedi-1 and MEGF10 (show MEGF10 Antibodies) can mediate phagocytosis independently through the recruitment of Syk (show SYK Antibodies).
Jedi is involved in the fine regulation of the early stages of hematopoietic differentiation, presumably through the Notch (show NOTCH1 Antibodies) signaling pathway.
a cellular and molecular mechanism by which neuronal corpses are culled during dorsal root ganglia development involves Jedi protein
PEAR1 is a platelet receptor that signals upon the formation of platelet-platelet contacts independent of platelet activation and secondary to platelet aggregation (Nanda et al., 2005
platelet endothelial aggregation receptor 1
, multiple EGF-like-domains 12
, platelet endothelial aggregation receptor 1-like
, multiple EGF-like domains protein 12
, multiple epidermal growth factor-like domains protein 12
, jagged and Delta protein
, protein Jedi