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anti-Pleckstrin Homology Domain Containing, Family A (phosphoinositide Binding Specific) Member 1 (PLEKHA1) Antibodies

PLEKHA1 encodes a pleckstrin homology domain-containing adapter protein. Additionally we are shipping PLEKHA1 Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PLEKHA1 361659  
PLEKHA1 59338 Q9HB21
PLEKHA1 101476 Q8BUL6
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Top anti-PLEKHA1 Antibodies at antibodies-online.com

Showing 10 out of 42 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-PLEKHA1 Antibody Titration: 0.2-1 ug/mlPositive Control: Human Lung 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of PLEKHA1 (arrow) using rabbit polyclonal PLEKHA1 Antibody (Center) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the PLEKHA1 gene. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$385.00
Details
Human Rabbit Alkaline Phosphatase (AP) ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated IP, WB PLEKHA1 MaxPab rabbit polyclonal antibody. Western Blot analysis of PLEKHA1 expression in mouse kidney. Immunoprecipitation of PLEKHA1 transfected lysate using anti-PLEKHA1 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead , and immunoblotted with PLEKHA1 purified MaxPab mouse polyclonal antibody (B01P) . 100 μL Log in to see 9 Days
$418.57
Details
Human Mouse Un-conjugated WB Western Blot analysis of PLEKHA1 expression in transfected 293T cell line by PLEKHA1 MaxPab polyclonal antibody.Lane 1: PLEKHA1 transfected lysate(44.44 KDa).Lane 2: Non-transfected lysate. 50 μL Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Biotin ELISA, WB   100 μg Log in to see 8 to 10 Days
$639.83
Details
Human Rabbit FITC WB   100 μg Log in to see 8 to 10 Days
$683.83
Details

PLEKHA1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Rat (Rattus)


Human ,
,

, , , , ,
Mouse (Murine)


More Antibodies against PLEKHA1 Interaction Partners

Human Pleckstrin Homology Domain Containing, Family A (phosphoinositide Binding Specific) Member 1 (PLEKHA1) interaction partners

  1. Studies indicate that the high-risk allele of the 10q26 locus encompasses three genes, PLEKHA1, ARMS2 (show ARMS2 Antibodies), and HTRA1 (show HTRA1 Antibodies) with high linkage disequilibrium.

  2. CX3CR1 (show CX3CR1 Antibodies) (T280M and V249I) and PLEKHA1 (A320T) polymorphisms were not found to be associated with age-related macular degeneration in an Indian population.

  3. This study provides evidence of the joint contribution of genetic variants in PLEKHA1/ARMS2 (show ARMS2 Antibodies)/HTRA1 (show HTRA1 Antibodies) to age-related macular degeneration risk.

  4. TAPP1 binds to protein tyrosine phosphatase PTPL1 (show PTPN13 Antibodies).

  5. syntrophins regulate the localization of TAPP1, which may be important for remodeling the actin cytoskeleton in response to growth factor stimulation

  6. PLEKHA1 is strongly implicated as primarily responsible for the evidence of linkage of age-related maculopathy (ARM) to the 10q26 locus and as a major contributor to ARM.susceptibility.

  7. Although a role for PLEKHA1 could not be totally excluded, there was a four times higher age-related macular degeneration risk was associated with haplotype "A-T-A" involving "PLEKHA1-LOC387715-HTRA1 (show HTRA1 Antibodies)" risk alleles.

  8. Independent of CFH (show CFH Antibodies) genotype or smoking history, an individual's risk of AMD (show AMD1 Antibodies) (age-related macular degeneration) could be increased or decreased, depending on their genotype or haplotype in the 10q26 region.

Mouse (Murine) Pleckstrin Homology Domain Containing, Family A (phosphoinositide Binding Specific) Member 1 (PLEKHA1) interaction partners

  1. Results identify TAPP1 as an important negative regulator of oligodendrocyte precursor cells differentiation through the Mek (show MDK Antibodies)/Erk (show EPHB2 Antibodies) signaling pathway.

  2. interacts with phosphatidylinositol (3,4)-bisphosphate thus regulating B-cell activation (show BLNK Antibodies) and autoantibody production

PLEKHA1 Antigen Profile

Protein Summary

This gene encodes a pleckstrin homology domain-containing adapter protein. The encoded protein is localized to the plasma membrane where it specifically binds phosphatidylinositol 3,4-bisphosphate. This protein may be involved in the formation of signaling complexes in the plasma membrane. Polymorphisms in this gene are associated with age-related macular degeneration. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 5.

Gene names and symbols associated with PLEKHA1

  • pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 (Plekha1) antibody
  • pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 (plekha1) antibody
  • pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 (PLEKHA1) antibody
  • AA960558 antibody
  • C920009D07Rik antibody
  • DKFZp459M1025 antibody
  • fc34a05 antibody
  • fc57h12 antibody
  • MGC83674 antibody
  • PLEKHA1 antibody
  • RGD1564153 antibody
  • TAPP1 antibody
  • wu:fc34a05 antibody
  • wu:fc57h12 antibody
  • zgc:55676 antibody

Protein level used designations for PLEKHA1

pleckstrin homology domain-containing family A member 1 , pleckstrin homology domain-containing protein family A member 1 , tandem PH domain containing protein-1 , pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 , tandem PH domain-containing protein 1 , PH domain-containing family A member 1 , TAPP-1

GENE ID SPECIES
361659 Rattus norvegicus
406745 Danio rerio
423940 Gallus gallus
446375 Xenopus laevis
450790 Pan troglodytes
477851 Canis lupus familiaris
513040 Bos taurus
549587 Xenopus (Silurana) tropicalis
100019790 Monodelphis domestica
100058481 Equus caballus
100174594 Pongo abelii
59338 Homo sapiens
101476 Mus musculus
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