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PODXL encodes a member of the sialomucin protein family. Additionally we are shipping Podocalyxin-Like Kits (46) and Podocalyxin-Like Proteins (23) and many more products for this protein.
Showing 10 out of 286 products:
Mouse (Murine) Monoclonal PODXL Primary Antibody for FACS - ABIN1108688
Doyonnas, Nielsen, Chelliah, Drew, Hara, Miyajima, McNagny: Podocalyxin is a CD34-related marker of murine hematopoietic stem cells and embryonic erythroid cells. in Blood 2005
Show all 4 references for ABIN1108688
Mouse (Murine) Monoclonal PODXL Primary Antibody for FACS - ABIN2853591
Minegishi, Suzuki, Yokomizo, Pan, Fujimoto, Takahashi, Hara, Miyajima, Nishikawa, Yamamoto: Expression and domain-specific function of GATA-2 during differentiation of the hematopoietic precursor cells in midgestation mouse embryos. in Blood 2003
Show all 4 references for ABIN2853591
Mouse (Murine) Monoclonal PODXL Primary Antibody for FACS - ABIN1108687
Minehata, Mukouyama, Sekiguchi, Hara, Miyajima: Macrophage colony stimulating factor modulates the development of hematopoiesis by stimulating the differentiation of endothelial cells in the AGM region. in Blood 2002
Show all 4 references for ABIN1108687
Mouse (Murine) Monoclonal PODXL Primary Antibody for FACS - ABIN1108686
Hara, Nakano, Tanaka, Tamura, Sekiguchi, Minehata, Copeland, Jenkins, Okabe, Kogo, Mukouyama, Miyajima: Identification of podocalyxin-like protein 1 as a novel cell surface marker for hemangioblasts in the murine aorta-gonad-mesonephros region. in Immunity 2000
Show all 4 references for ABIN1108686
Human Polyclonal PODXL Primary Antibody for IF (p), IHC (p) - ABIN675264
Xing, Ye, Chen, Hu, Chen: Hydrochloride pioglitazone protects diabetic rats against podocyte injury through preserving glomerular podocalyxin expression. in Arquivos brasileiros de endocrinologia e metabologia 2014
Human Monoclonal PODXL Primary Antibody for ELISA, WB - ABIN969355
Thomas, Schnaar, Konstantopoulos: Podocalyxin-like protein is an E-/L-selectin ligand on colon carcinoma cells: comparative biochemical properties of selectin ligands in host and tumor cells. in American journal of physiology. Cell physiology 2009
Dog (Canine) Polyclonal PODXL Primary Antibody for WB - ABIN374787
Nielsen, Graves, Chelliah, Vogl, Roskelley, McNagny: The CD34-related molecule podocalyxin is a potent inducer of microvillus formation. in PLoS ONE 2007
Human Polyclonal PODXL Primary Antibody for IHC, WB - ABIN2781992
Qiu, Xiang, Li, Krishnamoorthy, Chen, Wang: Profiling TRA-1-81 antigen distribution on a human embryonic stem cell. in Biochemical and biophysical research communications 2008
Human Polyclonal PODXL Primary Antibody for WB - ABIN2781991
Casey, Neville, Liu, Plummer, Cicek, Krumroy, Curran, McGreevy, Catalona, Klein, Witte: Podocalyxin variants and risk of prostate cancer and tumor aggressiveness. in Human molecular genetics 2006
Obese subjects showed evidence of renal alteration through the detection of a higher number of urinary podocalyxin positive cells.
Data show that both mucin16 (MUC16 (show MUC16 Antibodies)) and podocalyxin (PODXL)-E-selectin (show SELE Antibodies)-mediated interactions are mechanically stronger than like L-selectin (show SELL Antibodies) interactions at the single-molecule level.
In gastric cancer, PODXL expression by the polyclonal antibody HPA2110 is an independent marker of poor prognosis.
PCX (show PC Antibodies) promotes cisplatin chemoresistance in osteosarcoma cells through a PI3Kdependent mechanism.
EZR (show EZR Antibodies), CLIC5 (show CLIC5 Antibodies) and PODXL are overexpressed in hepatocellular carcinoma and may have a role in cell migration and invasiveness
PODXL up-regulates the expression level of Bmi1 (show BMI1 Antibodies) in OTSCC cells.
podocalyxin to be an independent factor for poor prognosis in PDAC. To our knowledge, this is the first such report of its prognostic value.
miR (show MLXIP Antibodies)-125b was found to be important in arteriosclerosis obliterans by suppressing the expression of PODXL and may serve as a potential therapeutic target for the treatment of arteriosclerosis obliterans.
We show that podocalyxin plays a key role in the formation of primary tumors and distant tumor metastasis.
PCLP1 expressed on breast tumor cells may function as an immunomodulatory molecule, which may represent a mechanism to evade the immune response.
when endogenous podocalyxin was removed from highly metastatic 4T1 mammary tumor cells there was a decrease in collective invasion . Podocalyxin is a tumor cell-intrinsic regulator of experimental collective tumor cell invasion and tumor budding.
Podocalyxin has a role in glioblastoma multiforme cell invasion and proliferation via beta-catenin (show CTNNB1 Antibodies) signaling
Loss of podocalyxin from the lung vasculature results in changes to the lung structure and function including increased lung volume when inflated under constant pressure (25 cm H2O) and changes to the matrix composition.
CTGF (show CTGF Antibodies) is an important mediator of high glucose-induced podocyte damage and decreases the protein level of podocalyxin by the ERK1/2 (show MAPK1/3 Antibodies) pathway.
platelet Podxl is involved in the control of hemostasis acting as a platelet co-stimulator, likely due to its pro-adhesive properties
Full-length recombinant murine podocalyxin recruits NHERF-1 (show SLC9A3R1 Antibodies) to the apical domain. Ectopic expression in human & canine epithelial cells leads to microvilli formation on an apical domain extending laterally to the junctional complexes.
Podocalyxin plays multiple roles in neural development
PODXL may act as a costimulator of agonists in the activation of platelets and formation of a stable thrombus.
Data show that in podocalyxin-deficient mice, the thickness of the main carotid artery is significantly increased, and there is an increased number of choroidal capillaries lining the ventricular spaces.
Podocalyxin mRNA was widely expressed at least from E14 (show NPAT Antibodies), the first age we studied, and expression remained high until adulthood
This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin.
, podocalyxin-like protein 1-like
, GCTM-2 antigen
, podocalyxin-like protein 1
, PC-like protein 1
, Podocalyxin-like protein 1