PODXL antibody (Extracellular, Intracellular, Transmembrane Domain)

Catalog No. ABIN3025406

This Mouse Monoclonal antibody specifically detects PODXL in WB, FACS, IF and IHC (p). It exhibits reactivity toward Human and Rat.

Quick Overview for PODXL antibody (Extracellular, Intracellular, Transmembrane Domain) (ABIN3025406)

Target: PODXL (Podocalyxin-Like (PODXL))

Reactivity: Human, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This PODXL antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: 3D3

Product Details anti-PODXL Antibody

Binding Specificity: Extracellular, Intracellular, Transmembrane Domain

Purpose: Podocalyxin Antibody (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogen: A human recombinant protein fragment containing the intracellular, transmembrane, and part of the extracellular domain was used as the immunogen for the Podocalyxin antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the Podocalyxin antibody to be titered up or down for optimal performance.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the Podocalyxin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for PODXL

Target: PODXL (Podocalyxin-Like (PODXL))

Alternative Name: Podocalyxin

Background: Podocalyxin is a member of the CD34 transmembrane sialomucin family. It is over-expressed on the podocyte foot projections and plays essential roles in kidney development and homeostasis, blood filtration and urine formation. It is also expressed on vascular endothelia, hematopoietic progenitors and a subset of neurons. Overexpression may be linked to more aggressive tumor behavior. Podocalyxin antibody can identify podocytes in the urine (podocyturia) that may indicate glomerular disease, pre-eclampsia, and other kidney pathology.

Pathways: Tube Formation