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Podocalyxin-Like Proteins (PODXL)

PODXL encodes a member of the sialomucin protein family. Additionally we are shipping Podocalyxin-Like Antibodies (276) and Podocalyxin-Like Kits (46) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PODXL 5420 O00592
PODXL 27205 Q9R0M4
PODXL 192181 Q9WTQ2
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Top Podocalyxin-Like Proteins at antibodies-online.com

Showing 10 out of 23 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
Yeast Rat His tag 50 μg Log in to see 31 to 36 Days
$341.00
Details
Yeast Human His tag 50 μg Log in to see 31 to 36 Days
$341.00
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 9 to 11 Days
$242.00
Details
HOST_Escherichia coli (E. coli) Human His tag,GST tag 100 μg Log in to see 11 to 13 Days
$724.90
Details
HOST_Escherichia coli (E. coli) Mouse His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$756.80
Details

PODXL Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Mouse (Murine) ,
, ,
Rat (Rattus) ,
,

More Proteins for Podocalyxin-Like (PODXL) Interaction Partners

Human Podocalyxin-Like (PODXL) interaction partners

  1. Obese subjects showed evidence of renal alteration through the detection of a higher number of urinary podocalyxin positive cells.

  2. Data show that both mucin16 (MUC16 (show MUC16 Proteins)) and podocalyxin (PODXL)-E-selectin (show SELE Proteins)-mediated interactions are mechanically stronger than like L-selectin (show SELL Proteins) interactions at the single-molecule level.

  3. In gastric cancer, PODXL expression by the polyclonal antibody HPA2110 is an independent marker of poor prognosis.

  4. PCX promotes cisplatin chemoresistance in osteosarcoma cells through a PI3Kdependent mechanism.

  5. EZR (show EZR Proteins), CLIC5 (show CLIC5 Proteins) and PODXL are overexpressed in hepatocellular carcinoma and may have a role in cell migration and invasiveness

  6. PODXL up-regulates the expression level of Bmi1 (show BMI1 Proteins) in OTSCC cells.

  7. podocalyxin to be an independent factor for poor prognosis in PDAC. To our knowledge, this is the first such report of its prognostic value.

  8. miR (show MLXIP Proteins)-125b was found to be important in arteriosclerosis obliterans by suppressing the expression of PODXL and may serve as a potential therapeutic target for the treatment of arteriosclerosis obliterans.

  9. We show that podocalyxin plays a key role in the formation of primary tumors and distant tumor metastasis.

  10. PCLP1 expressed on breast tumor cells may function as an immunomodulatory molecule, which may represent a mechanism to evade the immune response.

Mouse (Murine) Podocalyxin-Like (PODXL) interaction partners

  1. when endogenous podocalyxin was removed from highly metastatic 4T1 mammary tumor cells there was a decrease in collective invasion . Podocalyxin is a tumor cell-intrinsic regulator of experimental collective tumor cell invasion and tumor budding.

  2. Podocalyxin has a role in glioblastoma multiforme cell invasion and proliferation via beta-catenin (show CTNNB1 Proteins) signaling

  3. Loss of podocalyxin from the lung vasculature results in changes to the lung structure and function including increased lung volume when inflated under constant pressure (25 cm H2O) and changes to the matrix composition.

  4. CTGF is an important mediator of high glucose-induced podocyte damage and decreases the protein level of podocalyxin by the ERK1/2 pathway.

  5. platelet Podxl is involved in the control of hemostasis acting as a platelet co-stimulator, likely due to its pro-adhesive properties

  6. Full-length recombinant murine podocalyxin recruits NHERF-1 (show SLC9A3R1 Proteins) to the apical domain. Ectopic expression in human & canine epithelial cells leads to microvilli formation on an apical domain extending laterally to the junctional complexes.

  7. Podocalyxin plays multiple roles in neural development

  8. PODXL may act as a costimulator of agonists in the activation of platelets and formation of a stable thrombus.

  9. Data show that in podocalyxin-deficient mice, the thickness of the main carotid artery is significantly increased, and there is an increased number of choroidal capillaries lining the ventricular spaces.

  10. Podocalyxin mRNA was widely expressed at least from E14, the first age we studied, and expression remained high until adulthood

Podocalyxin-Like (PODXL) Protein Profile

Protein Summary

This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin.

Gene names and symbols associated with Podocalyxin-Like Proteins (PODXL)

  • podocalyxin-like (PODXL)
  • si:dkey-146n1.1 (si:dkey-146n1.1)
  • podocalyxin-like (LOC100614602)
  • podocalyxin-like (Podxl)
  • podocalyxin-like (LOC100512201)
  • podocalyxin-like protein 1 (PCLP1)
  • AW121214 protein
  • cPCLP1 protein
  • fc18d02 protein
  • Gp135 protein
  • Gp200 protein
  • Ly102 protein
  • MEP21 protein
  • PC protein
  • PCLP protein
  • PCLP-1 protein
  • PCLP1 protein
  • podocalyxin protein
  • Podxl protein
  • wu:fc18d02 protein

Protein level used designations for Podocalyxin-Like Proteins (PODXL)

podocalyxin-like , podocalyxin-like protein 1-like , GCTM-2 antigen , podocalyxin , podocalyxin-like protein 1 , PC-like protein 1 , Podocalyxin-like protein 1 , thrombomucin

GENE ID SPECIES
472604 Pan troglodytes
563365 Danio rerio
100462597 Pongo abelii
100614602 Pan troglodytes
5420 Homo sapiens
27205 Mus musculus
192181 Rattus norvegicus
482252 Canis lupus familiaris
100727578 Cavia porcellus
395755 Gallus gallus
616366 Bos taurus
101106679 Ovis aries
100512201 Sus scrofa
100009552 Oryctolagus cuniculus
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