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anti-Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1) Antibodies

PABPC1 encodes a poly(A) binding protein. Additionally we are shipping Poly(A) Binding Protein, Cytoplasmic 1 Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PABPC1 26986 P11940
PABPC1 18458 P29341
PABPC1 171350 Q9EPH8
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Top anti-Poly(A) Binding Protein, Cytoplasmic 1 Antibodies at antibodies-online.com

Showing 10 out of 45 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated IHC, WB WB Suggested Anti-PABPC1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: HepG2 cell lysate Sample Type: Human brain stem cells (NT2)  Primary Antibody Dilution: 1:500Secondary Antibody: Goat anti-rabbit Alexa Fluor 594 Secondary Antibody Dilution: 1:0000Color/Signal Descriptions: Red: PABPC1 Blue: DAPI  Gene Name: PABPC1 Submitted by: Dr. Yuzhi Chen, University of Arkansas for Medical Science 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of PABPC1 Antibody (Center) (ABIN389462) in NIH-3T3 cell line lysates (35 µg/lane). PABPC1 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human lung carcinoma reacted with PABPC1 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of PABPC1 Antibody (Center) in NIH-3T3 cell line lysates (35ug/lane). PABPC1 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Rabbit Mouse Un-conjugated ICC, FACS, IF, IP, ELISA, WB Western blot for anti-PABP on HeLa cell extracts (left lane) 50 μL Log in to see 5 to 6 Days
$402.29
Details
Human Rabbit Un-conjugated IHC (p), WB IHC-P Image PABP antibody [N1N2], N-term detects PABP protein at cytosol on mouse lung by immunohistochemical analysis. Sample: Paraffin-embedded mouse lung. PABP antibody [N1N2], N-term , dilution: 1:500. IHC-P Image PABP antibody [N1N2], N-term detects PABP protein at cytosol on mouse duodenum by immunohistochemical analysis. Sample: Paraffin-embedded mouse duodenum. PABP antibody [N1N2], N-term , dilution: 1:500. 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Mouse Un-conjugated IF, IP, ELISA, WB 50 μL Log in to see 8 to 10 Days
$573.83
Details
Human Rabbit Un-conjugated IF, WB Western Blot analysis of PABPC1 expression in transfected 293T cell line by PABPC1 MaxPab polyclonal antibody.Lane 1: PABPC1 transfected lysate(70.70 KDa).Lane 2: Non-transfected lysate. Immunofluorescence of purified MaxPab antibody to PABPC1 on HeLa cell. [antibody concentration 20 ug/ml] 100 μg Log in to see 9 Days
$418.57
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Lane 1: mouse heart lysates Lane 2: mouse kidney lysates probed with Anti PABP (Methyl Arg455/460) Polyclonal Antibody, Unconjugated (ABIN704831) at 1:200 in 4C. Followed by conjugation to secondary antibody at 1:3000 90min in 37C. Predicted band 75kD. Observed band size: 75kD Antigen: 2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Rabbit Anti-Goat IgG at 1: 5000;  TMB staining Read the data in Microplate Reader by 450nm. 100 μL Log in to see 3 to 7 Days
$291.50
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details

PABPC1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Poly(A) Binding Protein, Cytoplasmic 1 Antibodies

  1. Rabbit Monoclonal PABPC1 Primary Antibody for ICC, FACS - ABIN108539 : Görlach, Burd, Dreyfuss: The mRNA poly(A)-binding protein: localization, abundance, and RNA-binding specificity. in Experimental cell research 1994 (PubMed)
    Show all 3 references for ABIN108539

  2. Chicken Polyclonal PABPC1 Primary Antibody for IHC, WB - ABIN2778803 : Rivera, Lloyd: Modulation of enteroviral proteinase cleavage of poly(A)-binding protein (PABP) by conformation and PABP-associated factors. in Virology 2008 (PubMed)

  3. Human Polyclonal PABPC1 Primary Antibody for IHC (p), WB - ABIN389462 : Le Clerc, Limou, Coulonges, Carpentier, Dina, Taing, Delaneau, Labib, Sladek, , Deveau, Guillemain, Ratsimandresy, Montes, Spadoni, Therwath, Schächter, Matsuda, Gut, Lelièvre, Lévy, Froguel, Delfraissy, Hercberg, Zagury: Genomewide association study of a rapid progression cohort identifies new susceptibility alleles for AIDS (ANRS Genomewide Association Study 03). in The Journal of infectious diseases 2009 (PubMed)

  4. Human Polyclonal PABPC1 Primary Antibody for IF, WB - ABIN525792 : Higashi, Tomigahara, Shiraki, Miyata, Mikami, Kimura, Moro, Inagaki, Kaneko: A novel small compound that promotes nuclear translocation of YB-1 ameliorates experimental hepatic fibrosis in mice. in The Journal of biological chemistry 2011 (PubMed)

More Antibodies against Poly(A) Binding Protein, Cytoplasmic 1 Interaction Partners

Human Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1) interaction partners

  1. BTG2 (show BTG2 Antibodies) stimulates mRNA deadenylation via CAF1 (show CHAF1B Antibodies) activation through interaction with PABPC1. Interaction of BTG2 (show BTG2 Antibodies) with the first RRM domain of PABPC1 is required for BTG2 (show BTG2 Antibodies) to control cell proliferation.

  2. PABPC1 is a novel co-regulator of the AR

  3. PABPC1 is upregulated in gastric carcinoma tissues, and high PABPC1 expression predicts poor survival. PABPC1 regulates proliferation and transformation of gastric cancer cells in vitro and in vivo. PABPC1 knockdown induces apoptosis.

  4. PABPC1 interacts with AGO2 (show EIF2C2 Antibodies) and is responsible for the microRNA mediated gene silencing in high grade hepatocellular carcinoma.

  5. Poly(A) binding protein 1 enhances cap-independent translation initiation of neurovirulence factor from avian herpesvirus

  6. Metastatic duodenal cancer cells do not tolerate intracellular PABP1 accumulation and are thus exported into the extracellular milieu by the exosome-mediated pathway. In addition, PABP1 has a potential use as a biomarker for metastatic duodenal cancer.

  7. This study highlights PABP-1 as a protein that is important to the pathology of ALS and indicates that the proteomic profile of TDP-43 inclusions in ALS may differ depending on the causative genetic mutation.

  8. PABPC1 is mislocalized in spinal cord motor neurons in amyotrophic lateral sclerosis.

  9. Study shows that PABP specifically regulates iNOS (show NOS2 Antibodies) mRNA stability in human DLD (show DLD Antibodies)-1 cells by binding to different sites in the 50- and 30-UTR (show UTS2R Antibodies) of the iNOS (show NOS2 Antibodies) mRNA. .

  10. These results suggest that production of the NSs protein during rift valley fever virus infection leads to sequestration of PABP1 in the nuclear speckles, creating a state within the cell that favors viral protein production.

Mouse (Murine) Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1) interaction partners

  1. Data (including data from studies in knockout mice) suggest that Epab (embryonic poly(A)-binding protein), which is oocyte specific, is required for ability of cumulus cells and granulosa cells to exhibit responsiveness to Egf/Egfr (show EGFR Antibodies) signaling.

  2. Epab(-/-) oocytes are smaller in size, contain peripheral germinal vesicles, and are loosely associated with cumulus cells

  3. These findings suggest that EPAB may predominantly play roles in translational regulation of the mRNAs during early oogenesis and folliculogenesis, but PABPC1 most likely perform these roles in the later terms of ovarian development along with EPAB

  4. Epab is dispensable for mouse spermatogenesis and male fertility.

  5. We analyzed the expression of sperm-specific Akap3 (show AKAP3 Antibodies) and the potential regulatory factors of its protein synthesis during mouse spermiogenesis.

  6. Both Epab and Pabpc1 expression increase during early postnatal life and reach their peak at D32 testis.

  7. our data support the concept that expanded ATXN2 (show ATXN2 Antibodies) undergoes progressive insolubility and affects PABPC1 by a toxic gain-of-function mechanism with tissue-specific effects, which may be partially alleviated by the induction of FBXW8 (show FBXW8 Antibodies).

  8. EPAB is necessary for oogenesis, folliculogenesis and female fertility in mice.

  9. PABPC2 was present in pachytene spermatocytes and round spermatids, whereas elongating spermatids still included PABPC1.

Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1) Antigen Profile

Protein Summary

This gene encodes a poly(A) binding protein. The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly(A) tail of eukaryotic messenger RNAs via RNA-recognition motifs. The binding of this protein to poly(A) promotes ribosome recruitment and translation initiation\; it is also required for poly(A) shortening which is the first step in mRNA decay. The gene is part of a small gene family including three protein-coding genes and several pseudogenes.

Gene names and symbols associated with PABPC1

  • poly(A) binding protein, cytoplasmic 1-like (pabpc1l) antibody
  • poly(A) binding protein, cytoplasmic 1 (pabpc1) antibody
  • poly(A) binding protein, cytoplasmic 1-like (PABPC1L) antibody
  • poly A binding protein, cytoplasmic 1 a (pabpc1a) antibody
  • poly(A) binding protein, cytoplasmic 1 (pabpc1-a) antibody
  • poly(A) binding protein, cytoplasmic 1 (PABPC1) antibody
  • poly(A) binding protein, cytoplasmic 1 (Pabpc1) antibody
  • ePAB antibody
  • fi20g03 antibody
  • pab-2 antibody
  • PAB1 antibody
  • Pabp antibody
  • Pabp1 antibody
  • pabpc1 antibody
  • PABPC2 antibody
  • PabpI antibody
  • Pabpl1 antibody
  • wu:fb16a02 antibody
  • wu:fi19b08 antibody
  • wu:fi20g03 antibody
  • wu:fj12d09 antibody
  • wu:fj61f06 antibody
  • zgc:55855 antibody
  • zgc:109879 antibody

Protein level used designations for PABPC1

polyadenylate-binding protein 1-like , poly(A) binding protein, cytoplasmic 1 , polyadenylate-binding protein 1 , PABP 1-A , PABP-1-A , PABP-A , cytoplasmic poly(A)-binding protein 1-A , poly(A)-binding protein 1-A , polyadenylate-binding protein 1-A , xPABP1-A , poly(A) binding protein, cytoplasmic 2 , PABP 1 , PABP-1 , poly(A)-binding protein 1 , poly A binding protein 1

GENE ID SPECIES
327625 Danio rerio
448595 Xenopus (Silurana) tropicalis
711882 Macaca mulatta
606498 Danio rerio
379896 Xenopus laevis
430997 Gallus gallus
26986 Homo sapiens
612751 Canis lupus familiaris
282296 Bos taurus
18458 Mus musculus
171350 Rattus norvegicus
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