anti-Polyhomeotic Homolog 3 (Drosophila) (PHC3) Antibodies

Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. Additionally we are shipping Polyhomeotic Homolog 3 (Drosophila) Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PHC3 310258  
PHC3 80012 Q8NDX5
PHC3 241915 Q8CHP6
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Top anti-Polyhomeotic Homolog 3 (Drosophila) Antibodies at antibodies-online.com

Showing 10 out of 14 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: PHC3 Antibody [NBP1-84896] - Staining of human cell line A-431 shows positivity in vesicles, actin filaments & nucleus but excluded from the nucleoli. Antibody staining is shown in green. Immunohistochemistry-Paraffin: PHC3 Antibody [NBP1-84896] - Staining of human kidney shows strong granular cytoplasmic positivity in cells in tubules and moderate nuclear staining in cells in glomeruli. 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Human Rabbit Un-conjugated IC, IF, WB Immunofluorescent analysis of PHC3 staining in U2OS cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody i Western blot analysis of PHC3 expression in Hela (A) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated IP, WB Western Blot: PHC3 Antibody [ABIN2622642] - Detection of Human PHC3 by Western Blot and Immunoprecipitation. Samples: Whole cell lysate (5, 15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-PHC3 antibody ABIN2622642 used for WB at 0.1 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 3 mcg/mg lysate. PHC3 was also immunoprecipitated by another rabbit anti-PHC3 antibody, which recognizes a downstream epitope. 100 μL Log in to see 7 to 9 Days
$486.94
Details
Human Rabbit Un-conjugated IP 100 μL Log in to see 7 to 9 Days
$486.94
Details
Human Rabbit Un-conjugated IF, IHC, WB Immunofluorescence analysis of U2OS cell using PHC3 antibody. Blue: DAPI for nuclear staining. 100 μL Log in to see 16 Days
$323.13
Details
Human Rabbit Un-conjugated ICC, IF Immunocytochemistry/Immunofluorescence: PHC3 Antibody  - Staining of human cell line A549 shows localization to nucleus. 100 μL Log in to see 10 to 13 Days
$439.69
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated IF, WB Western Blot analysis of PHC3 expression in transfected 293T cell line by PHC3 MaxPab polyclonal antibody.Lane 1: PHC3 transfected lysate(16.61 KDa).Lane 2: Non-transfected lysate. Immunofluorescence of purified MaxPab antibody to PHC3 on HeLa cell. [antibody concentration 10 ug/ml] 50 μL Log in to see 11 to 12 Days
$430.00
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 7 to 9 Days
$537.17
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 15 to 19 Days
$466.62
Details

PHC3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Rat (Rattus)


Human , ,
,

Mouse (Murine)


Top referenced anti-Polyhomeotic Homolog 3 (Drosophila) Antibodies

  1. Human Polyclonal PHC3 Primary Antibody for ICC, IF - ABIN4345165 : Choi, Kim, Cho, Lee, Yi, Eun, Kim, Woo, Choi, Whangbo, Choi, Noh, Moon: Noninvasive identification of viable cell populations in docetaxel-treated breast tumors using ferritin-based magnetic resonance imaging. in PLoS ONE 2013 (PubMed)

More Antibodies against Polyhomeotic Homolog 3 (Drosophila) Interaction Partners

Human Polyhomeotic Homolog 3 (Drosophila) (PHC3) interaction partners

  1. Data show that polycomb (show CBX2 Antibodies)-group proteins BMI1 (show BMI1 Antibodies), PHC3, CBX6 (show CBX6 Antibodies) and CBX7 (show CBX7 Antibodies) expression was significantly increased during imatinib treatment.

  2. PHC3 amplification may emerge as a biomarker in cancer.

  3. SAM (show TTN Antibodies) linker controls PHC3 SAM (show TTN Antibodies) polymerization

  4. PHC3 is a tumor suppressor in osteosarcoma cells abd its suppression may be caused by modification of polycomb (show CBX2 Antibodies) repressive complex 1 in cancer cells.

  5. loss of PHC3 may favor tumorigenesis by potentially disrupting the ability of cells to remain in G(0)

Polyhomeotic Homolog 3 (Drosophila) (PHC3) Antigen Profile

Protein Summary

Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones\; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility (By similarity).

Gene names and symbols associated with PHC3

  • polyhomeotic homolog 3 (Drosophila) (Phc3) antibody
  • polyhomeotic homolog 3 (Drosophila) (PHC3) antibody
  • polyhomeotic like 3 (LOC100346297) antibody
  • polyhomeotic-like 3 (Drosophila) (Phc3) antibody
  • E030046K01Rik antibody
  • Edr3 antibody
  • Hph3 antibody

Protein level used designations for PHC3

polyhomeotic-like protein 3 , polyhomeotic like 3 , polyhomeotic homolog 3 (Drosophila) , early development regulator 3 , early development regulatory protein 3 , homolog of polyhomeotic 3 , polyhomeotic 3

GENE ID SPECIES
310258 Rattus norvegicus
460843 Pan troglodytes
100346297 Oryctolagus cuniculus
80012 Homo sapiens
241915 Mus musculus
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