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Polymerase (RNA) III (DNA Directed) Polypeptide A, 155kDa Proteins (POLR3A)

The protein encoded by POLR3A is the catalytic component of RNA polymerase III, which synthesizes small RNAs. Additionally we are shipping Polymerase (RNA) III (DNA Directed) Polypeptide A, 155kDa Antibodies (27) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Mouse POLR3A POLR3A 218832  
Rat POLR3A POLR3A 361102  
POLR3A 11128 O14802
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Top Polymerase (RNA) III (DNA Directed) Polypeptide A, 155kDa Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Human His-SUMO Tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details

POLR3A Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
, ,

More Proteins for Polymerase (RNA) III (DNA Directed) Polypeptide A, 155kDa (POLR3A) Interaction Partners

Human Polymerase (RNA) III (DNA Directed) Polypeptide A, 155kDa (POLR3A) interaction partners

  1. Mutations in POLR3A or POLR3B (show POLR3B Proteins) are rare in patients with unclassified hypomyelination.

  2. Mutations in POLR3A are associated with a more severe clinical course of 4H leukodystrophy.

  3. MRI (show C7ORF49 Proteins) in patients with POLR3B (show POLR3B Proteins) mutations revealed smaller cerebellar structures, especially vermis, than those in POLR3A mutations. MRI (show C7ORF49 Proteins) also showed milder hypomyelination in patients with POLR3B (show POLR3B Proteins) mutations than those with POLR3A mutations

  4. Investigated POLR3A and POLR3B (show POLR3B Proteins) mutations in patients with genetically unexplained hypomyelinating leukodystrophies with features of Pol III-related leukodystrophies. Recessive mutations in POLR3A or POLR3B (show POLR3B Proteins) were uncovered in all 14 patients.

  5. Studies indicate that aatients with anti-RNAP have an increased risk of malignancy within a 5-year timeframe before or after onset of systemic sclerosis (SSc (show CYP11A1 Proteins)) skin changes.

  6. Mutations in POLR3A and POLR3B encoding RNA Polymerase III subunits cause an autosomal-recessive hypomyelinating leukoencephalopathy

  7. Mutations of POLR3A encoding a catalytic subunit of RNA polymerase Pol III cause a recessive hypomyelinating leukodystrophy.

Polymerase (RNA) III (DNA Directed) Polypeptide A, 155kDa (POLR3A) Protein Profile

Protein Summary

The protein encoded by this gene is the catalytic component of RNA polymerase III, which synthesizes small RNAs. The encoded protein also acts as a sensor to detect foreign DNA and trigger an innate immune response.

Gene names and symbols associated with POLR3A

  • polymerase (RNA) III (DNA directed) polypeptide A (Polr3a)
  • polymerase (RNA) III (DNA directed) polypeptide A, 155kDa (POLR3A)
  • 9330175N20Rik protein
  • ADDH protein
  • BC053071 protein
  • HLD7 protein
  • hRPC155 protein
  • RGD1305574 protein
  • RPC1 protein
  • RPC155 protein

Protein level used designations for POLR3A

DNA-directed RNA polymerase III subunit RPC1 , polymerase (RNA) III (DNA directed) polypeptide A, 155kDa , DNA-directed RNA polymerase III largest subunit , DNA-directed RNA polymerase III subunit A , RNA polymerase III 155 kDa subunit , RNA polymerase III subunit C1 , RNA polymerase III subunit C160 , RNA polymerase III subunit RPC155-D

GENE ID SPECIES
218832 Mus musculus
361102 Rattus norvegicus
11128 Homo sapiens
479256 Canis lupus familiaris
540308 Bos taurus
423727 Gallus gallus
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