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Potassium Inwardly-Rectifying Channel, Subfamily J, Member 12 Proteins (KCNJ12)

KCNJ12 encodes an inwardly rectifying K+ channel which may be blocked by divalent cations. Additionally we are shipping Potassium Inwardly-Rectifying Channel, Subfamily J, Member 12 Antibodies (81) and Potassium Inwardly-Rectifying Channel, Subfamily J, Member 12 Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
KCNJ12 3768 Q14500
Rat KCNJ12 KCNJ12 117052  
KCNJ12 16515 P52187
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Top Potassium Inwardly-Rectifying Channel, Subfamily J, Member 12 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

KCNJ12 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine) ,
,

More Proteins for Potassium Inwardly-Rectifying Channel, Subfamily J, Member 12 (KCNJ12) Interaction Partners

Human Potassium Inwardly-Rectifying Channel, Subfamily J, Member 12 (KCNJ12) interaction partners

  1. The augmentation of Ca(2 (show CA2 Proteins)+) influx and cytokine release suggests a physiological role for Kir2.2 in TLR4 (show TLR4 Proteins)-stimulated monocytes.

  2. Unconventional role of the inwardly rectifying potassium channel (show KCNAB2 Proteins) Kir2.2 as a constitutive activator of RelA (show NFkBP65 Proteins) in cancer.

  3. Kir2.1 (show KCNJ2 Proteins) and Kir2.2 have two distinct lipid requirements for activity.

  4. Kir2.2 knockdown induces senescence of cancer cells by a mechanism involving reactive oxygen species accumulation.

  5. Kir2.1 (show KCNJ2 Proteins) and Kir2.2 subunits exert neither a dominant nor an anomalous effect on any of the properties of heteromeric channels.

  6. KIr2.1 (show KCNJ2 Proteins) and Kir2.2 are directly activated by membrane phosphatidylinositol 4,5-bisphosphate.

  7. Molecular cloning of functional KCNJ12 with an arginine residue at position 285.

  8. transcripts for Kir2.2 potassium channels are identified in proliferative smooth muscle cells

  9. Kir2.2 and Kir2.1 (show KCNJ2 Proteins) are primary determinants of endogenous K(+) conductance in HAECs under resting conditions and that Kir2.2 provides the dominant conductance in these cells.

  10. Results describe the regulation of inwardly rectifying potassium current and its main molecular correlates, Kir2.1 (show KCNJ2 Proteins), Kir2.2 and Kir2.3 (show KCNJ4 Proteins) channels, by endothelin-1 (show EDN1 Proteins) in human atrial cardiomyocytes.

Mouse (Murine) Potassium Inwardly-Rectifying Channel, Subfamily J, Member 12 (KCNJ12) interaction partners

  1. Kir2.2 in the brainstem plays a transient role in hypercapnic ventilatory response , possibly through central ventilatory chemosensitivity, during postnatal development.

  2. Computer simulations grounded in biophysical measurements of prelimbic and infralimbic cortex slices suggest a dynamic interaction among Kir2, Kleak, and HCN channel currents in shaping membrane potential and temporal integration of synaptic potentials.

Potassium Inwardly-Rectifying Channel, Subfamily J, Member 12 (KCNJ12) Protein Profile

Protein Summary

This gene encodes an inwardly rectifying K+ channel which may be blocked by divalent cations. This protein is thought to be one of multiple inwardly rectifying channels which contribute to the cardiac inward rectifier current (IK1). The gene is located within the Smith-Magenis syndrome region on chromosome 17.

Gene names and symbols associated with KCNJ12

  • potassium inwardly-rectifying channel, subfamily J, member 12 (KCNJ12)
  • potassium inwardly-rectifying channel, subfamily J, member 12 (Kcnj12)
  • hIRK protein
  • hIRK1 protein
  • hkir2.2x protein
  • IRK protein
  • IRK-2 protein
  • IRK2 protein
  • kcnj12x protein
  • KCNJN1 protein
  • Kir2.1 protein
  • KIR2.2 protein
  • Kir2.2v protein
  • MB-IRK2 protein

Protein level used designations for KCNJ12

ATP-sensitive inward rectifier potassium channel 12 , inward rectifier K(+) channel Kir2.2 , potassium channel, inwardly rectifying subfamily J member 12 , potassium inwardly-rectifying channel, subfamily J, member 12 , inwardly-rectifying potassium channel Kir2.2 , inward rectifier K(+) channel Kir2.2v , inward rectifier K(+) channel Kir2.6 , potassium inwardly-rectifying channel, subfamily J, inhibitor 1 , IRK-2 , atrium potassium channel IRK , potassium inwardly-rectifying channel J12

GENE ID SPECIES
427662 Gallus gallus
705326 Macaca mulatta
746628 Pan troglodytes
100169698 Cavia porcellus
3768 Homo sapiens
117052 Rattus norvegicus
403760 Canis lupus familiaris
538479 Bos taurus
16515 Mus musculus
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