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Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. Additionally we are shipping KCNJ15 Antibodies (38) and many more products for this protein.
Showing 3 out of 6 products:
KCNJ15 couples with polyamines in sensing weak electric fields.
RNA-seq evidence of biallelic expression of KCNJ15 and 10 neighboring genes in at least one primary human tissue tested indicates that the expression of KCNJ15 is uncoupled from the control of the maternally inherited 5mCpG imprints at the WRB (show WRB Proteins) differentially methylated region (DMR (show WDR20 Proteins)) in disomic controls or trisomy (Down syndrome) individuals.
KCNJ15 has a major role in histamine-stimulated gastric acid secretion.
We had performed a replication study using an independent larger Japanese population for the association of rs3746876 within KCNJ15, and observed a significant association of rs3746876 with type 2 diabetes, but this study failed to find original finding.
It was shown that downregulation of Kcnj15 leads to increased insulin (show INS Proteins) secretion in vitro and in vivo. The mechanism for regulating insulin (show INS Proteins) secretion inolved a calcium-sensiong receptor.
KCNJ15 is a previously unreported susceptibility gene for T2DM among Asians
The potential synergy and consequences of the overexpression of KIR4.2 and KIR3.2 (show KCNJ6 Proteins) in Down's syndrome brain development are discussed.
Calcium-sensing receptor (show CASR Proteins) interacts directly with Kir4.1 (show KCNJ10 Proteins) and Kir4.2 and can decrease their currents.
MUPP1 and Kir4.2 may participate in a protein complex in the nephron that could regulate transport of K(+) as well as other ions.
Data show that KCNJ15 inward rectifier potassium channel and hyperpolarization-activated cyclic nucleotide-gated (HCN) channel currents are changed in Trisomic neuron.
in nonsecreting parietal cells, KCNJ15 is stored in vesicles distinct from the H(+)-K(+)-ATPase (show ATP4b Proteins)-enriched tubulovesicles. Furthermore, upon stimulation, KCNJ15 and H(+)-K(+)-ATPase (show ATP4b Proteins) both translocate to the apical membrane for active acid secretion.
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Eight transcript variants encoding the same protein have been found for this gene.
potassium inwardly-rectifying channel, subfamily J, member 15
, ATP-sensitive inward rectifier potassium channel 15
, potassium inwardly-rectifying channel J15
, Potassium channel, inwardly rectifying subfamily J member 15
, inward rectifier K(+) channel Kir1.3
, inward rectifier K(+) channel Kir4.2
, inward rectifier K+ channel KIR4.2
, potassium channel, inwardly rectifying subfamily J member 15
, inward rectifier K+ channel Kir4.2
, inwardly rectifying potassium channel Kir1.3