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Pre T-Cell Antigen Receptor alpha Proteins (PTCRA)

The protein encoded by PTCRA is a single-pass type I membrane protein that is found in immmature but not mature T-cells. Additionally we are shipping PTCRA Antibodies (22) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PTCRA 19208 P0C6B2
PTCRA 171558 Q6ISU1
PTCRA 116462 P0C6B3
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Top PTCRA Proteins at antibodies-online.com

Showing 6 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,297.17
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,311.83
Details

PTCRA Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
,
Human ,
,
Rat (Rattus)

More Proteins for Pre T-Cell Antigen Receptor alpha (PTCRA) Interaction Partners

Mouse (Murine) Pre T-Cell Antigen Receptor alpha (PTCRA) interaction partners

  1. pre-TCR expression is not essential for thymic differentiation to DP cells or for V-DJbeta suppression

  2. Combined expression of pTalpha and Notch3 (show NOTCH3 Proteins) in T cell leukemia identifies the requirement of preTCR for leukemogenesis

  3. The cytoplasmic tail of pTalpha plays a critical role in T lymphocyte development.

  4. pTalpha plays a role in protecting developing thymocytes from DNA damage in mice

  5. the dosage of E2A (show TCF3 Proteins), HEB, and SCL (show TAL1 Proteins) determines pT alpha gene expression in immature T cells

  6. when in competition with pTalpha, TCRalpha induced defective proliferation, survival, and differentiation of alphabeta T lymphocyte precursors

Human Pre T-Cell Antigen Receptor alpha (PTCRA) interaction partners

  1. Combined expression of pTalpha and Notch3 (show NOTCH3 Proteins) in T cell leukemia identifies the requirement of preTCR for leukemogenesis

  2. High levels of pre-T cell receptor alpha-chain mRNA splice forms have been demonstrated in immature CD2 (show CD2 Proteins)+CD7 (show CDK7 Proteins)+CD3 (show CD3 Proteins)- T cells of the jejunal mucosa, both intraepithelially and in lamina propria.

  3. identified a polyproline-arginine sequence in the pTalpha cytoplasmic tail that interacted in vitro with SH3 domains of the CIN85 (show SH3KBP1 Proteins)/CMS (show Cd2ap Proteins) family of adaptors, and mediated the recruitment of multiprotein complexes involving all (CMS (show Cd2ap Proteins), CIN85 (show SH3KBP1 Proteins), and CD2BP3 (show SH3KBP1 Proteins)) members

PTCRA Protein Profile

Protein Summary

The protein encoded by this gene is a single-pass type I membrane protein that is found in immmature but not mature T-cells. Along with TCRB and CD3 complex, the encoded protein forms the pre-T-cell receptor complex, which regulates early T-cell development. Four transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with PTCRA

  • pre T cell antigen receptor alpha (Ptcra)
  • pre T-cell antigen receptor alpha (PTCRA)
  • pre T-cell antigen receptor alpha (Ptcra)
  • gp33 protein
  • PT-ALPHA protein
  • pT-alpha-TCR protein
  • PTA protein
  • pTalpha protein
  • pT[a] protein

Protein level used designations for PTCRA

pre T-cell antigen receptor alpha , pT-alpha-TCR , pre-T-cell receptor alpha chain , pT-alpha , pTa

GENE ID SPECIES
19208 Mus musculus
171558 Homo sapiens
116462 Rattus norvegicus
513669 Bos taurus
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