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PFDN5 encodes a member of the prefoldin alpha subunit family. Additionally we are shipping PFDN5 Antibodies (83) and PFDN5 Kits (23) and many more products for this protein.
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Human PFDN5 Protein expressed in Escherichia coli (E. coli) - ABIN667517
Mori, Maeda, Kitaura, Taira, Iguchi-Ariga, Ariga: MM-1, a novel c-Myc-associating protein that represses transcriptional activity of c-Myc. in The Journal of biological chemistry 1998
Show all 2 references for ABIN667517
a genetic disruption in the murine Pfdn5 gene, a subunit of prefoldin, causes a syndrome characterized by photoreceptor degeneration, central nervous system abnormalities, and male infertility
MM-1 may play a role in liver development and growth.
knockdown of PFD2 (show PFDN2 Proteins) and PFD5 disrupted prefoldin formation in HTT (show HTT Proteins)-expressing cells, resulting in accumulation of aggregates of a pathogenic form of HTT (show HTT Proteins) and in induction of cell death.
Rabring7 (show RNF115 Proteins) stimulates c-Myc (show MYC Proteins) degradation via mono-ubiquitination of MM-1
interaction with p73 (show TP73 Proteins)
MM-1alpha, MM-1gamma, and MM-1gamma, but not MM-1beta, were found to repress transcription activity of c-Myc (show MYC Proteins)
Wnt4 (show WNT4 Proteins) gene, a member of the Wnt (show WNT2 Proteins)-beta-catenin (show CTNNB1 Proteins) pathway, was identified as a target gene of MM-1.
MM-1, a c-Myc (show MYC Proteins) interacting protein, interacts with HCV ARFP/F protein (show HPD Proteins), which can result in the enhancement of the c-Myc (show MYC Proteins) activity.
This gene encodes a member of the prefoldin alpha subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. The encoded protein may also repress the transcriptional activity of the proto-oncogene c-Myc. Alternatively spliced transcript variants encoding different isoforms have been described.
prefoldin subunit 5
, Prefoldin subunit 5
, C-myc-binding protein Mm-1
, c-myc binding protein MM-1
, myc modulator 1
, c-myc binding protein
, myc modulator-1
, prefoldin 5