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PFDN5 encodes a member of the prefoldin alpha subunit family. Additionally we are shipping PFDN5 Antibodies (84) and PFDN5 Kits (13) and many more products for this protein.
Showing 10 out of 14 products:
Human PFDN5 Protein expressed in Escherichia coli (E. coli) - ABIN667517
Mori, Maeda, Kitaura, Taira, Iguchi-Ariga, Ariga: MM-1, a novel c-Myc-associating protein that represses transcriptional activity of c-Myc. in The Journal of biological chemistry 1998
Show all 2 references for ABIN667517
a genetic disruption in the murine Pfdn5 gene, a subunit of prefoldin, causes a syndrome characterized by photoreceptor degeneration, central nervous system abnormalities, and male infertility
MM-1 may play a role in liver development and growth.
knockdown of PFD2 (show PFDN2 Proteins) and PFD5 disrupted prefoldin formation in HTT (show HTT Proteins)-expressing cells, resulting in accumulation of aggregates of a pathogenic form of HTT (show HTT Proteins) and in induction of cell death.
Rabring7 (show RNF115 Proteins) stimulates c-Myc (show MYC Proteins) degradation via mono-ubiquitination of MM-1
interaction with p73 (show TP73 Proteins)
MM-1alpha, MM-1gamma, and MM-1gamma, but not MM-1beta, were found to repress transcription activity of c-Myc (show MYC Proteins)
Wnt4 (show WNT4 Proteins) gene, a member of the Wnt (show WNT2 Proteins)-beta-catenin (show CTNNB1 Proteins) pathway, was identified as a target gene of MM-1.
MM-1, a c-Myc (show MYC Proteins) interacting protein, interacts with HCV ARFP/F protein (show HPD Proteins), which can result in the enhancement of the c-Myc (show MYC Proteins) activity.
This gene encodes a member of the prefoldin alpha subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. The encoded protein may also repress the transcriptional activity of the proto-oncogene c-Myc. Alternatively spliced transcript variants encoding different isoforms have been described.
prefoldin subunit 5
, Prefoldin subunit 5
, C-myc-binding protein Mm-1
, c-myc binding protein MM-1
, myc modulator 1
, c-myc binding protein
, myc modulator-1
, prefoldin 5