Pro-Platelet Basic Protein (Chemokine (C-X-C Motif) Ligand 7) Proteins (PPBP)

The protein encoded by PPBP is a platelet-derived growth factor that belongs to the CXC chemokine family. Additionally we are shipping Pro-Platelet Basic Protein (Chemokine (C-X-C Motif) Ligand 7) Antibodies (120) and Pro-Platelet Basic Protein (Chemokine (C-X-C Motif) Ligand 7) Kits (51) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PPBP 57349  
PPBP 5473 P02775
PPBP 246358  
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Top Pro-Platelet Basic Protein (Chemokine (C-X-C Motif) Ligand 7) Proteins at antibodies-online.com

Showing 10 out of 57 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human GST tag Pro-Platelet Basic Protein (Chemokine (C-X-C Motif) Ligand 7) (PPBP) (AA 59-125), (partial) protein (GST tag) 50 μg Log in to see 13 to 16 Days
$242.00
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated 25 μg Log in to see 10 to 12 Days
$320.68
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 25 μg Log in to see 10 to 12 Days
$320.68
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated Validation with Western Blot 10 μg Log in to see 12 to 15 Days
$345.35
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details
HOST_Human Cells Cynomolgus Fc Tag 10 μg Log in to see 20 to 21 Days
$173.80
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 100 μg Log in to see 15 to 19 Days
$319.00
Details
Yeast Cynomolgus His tag SDS-PAGE 100 μg Log in to see 20 to 21 Days
$612.15
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   10 μg Log in to see 3 to 4 Days
$85.00
Details

PPBP Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , , , , ,
, ,
Rat (Rattus) , ,
,

More Proteins for Pro-Platelet Basic Protein (Chemokine (C-X-C Motif) Ligand 7) (PPBP) Interaction Partners

Mouse (Murine) Pro-Platelet Basic Protein (Chemokine (C-X-C Motif) Ligand 7) (PPBP) interaction partners

  1. This is the first report that demonstrates Ppbp as a novel biomarker in the bronchial airway for lung cancer diagnosis.

  2. Platelet-derived CXCL7 and CXCL4 (show PF4 Proteins) contribute to the pathogenesis of acute lung injury.

  3. The findings suggest that CXCL7 attracts macrophages especially at the tumor site and may accelerate lung tumor development in the early stages.

  4. These results suggest that Cxcl4 (show PF4 Proteins) and Cxcl7 play a role in the development of neurobehavioral alterations that are triggered by in utero TCDD exposure and later surface in adults.

Human Pro-Platelet Basic Protein (Chemokine (C-X-C Motif) Ligand 7) (PPBP) interaction partners

  1. Two haplotype blocks, one upstream to the coding region of UGT2A1 (rs146712414, P = 9.1 x 10(-5); odds ratio [OR], 1.34; 95% confidence interval [CI], 1.16-1.56) and one downstream of the genes PF4/PPBP/CXCL5 (rs1595009, P = 1.3 x 10(-4); OR, 1.32; 95% CI, 1.15-1.52), were associated with AgP.

  2. Cby's C-terminal domain alone binds to TC-1 with significantly greater affinity compared to full-length Cby (show CBY1 Proteins), implying that target binding of the coiled-coil domain is affected by the flanking disordered regions.

  3. CXCL7 plays a promoting role in regulating the growth and metastasis of cholangiocarcinoma.

  4. Data suggest that neutrophil-activating peptide 2 (NAP-2) secreted by NK cells can bind to CXC Chemokine Receptor (show CXCR4 Proteins) 2 (CXCR2 (show CXCR2 Proteins)) on mesenchymal stem cells (MSCs) leading to stimulation of its recruitment.

  5. Utilizing mass spectrometry-based proteomics, platelet basic protein has been identified as a candidate serum biomarker for transient ischemic attack

  6. Synovial Cxcl7 mRNA and protein were increased in early rheumatoid arthritis compared to uninflamed controls and resolving arthritis.

  7. Studied and characterized the dynamics and thermodynamic stability of monomer and homodimer structures of CXCL7.

  8. Leptin (show LEP Proteins) and neutrophil-activating peptide act synergistically to promote mesenchymal stem cell senescence through enhancement of the PI3K (show PIK3CA Proteins)/Akt (show AKT1 Proteins) signaling pathway in systemic lupus erythematosus patients.

  9. CXCL7/CXCR2 (show CXCR2 Proteins) signalling pathways are a predictive factor of poor outcome in metastatic colon cancer.

  10. CXCR4 (show CXCR4 Proteins)-CXCL12 (show CXCL12 Proteins)-CXCR7 (show CXCR7 Proteins) regulates mTOR (show FRAP1 Proteins) signaling in renal cancer cells.

Pro-Platelet Basic Protein (Chemokine (C-X-C Motif) Ligand 7) (PPBP) Protein Profile

Protein Summary

The protein encoded by this gene is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells.

Gene names and symbols associated with PPBP

  • Platelet basic protein (scyb7)
  • pro-platelet basic protein (Ppbp)
  • pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) (PPBP)
  • pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) (Ppbp)
  • 2400003M24Rik protein
  • AI854500 protein
  • B-TG1 protein
  • Beta-TG protein
  • CTAP-III protein
  • CTAP3 protein
  • CTAPIII protein
  • CTAPIII/NAP-2 protein
  • CXCL7 protein
  • LA-PF4 protein
  • LDGF protein
  • MDGF protein
  • Nap-2 protein
  • NAP-2-L1 protein
  • PBP protein
  • SCYB7 protein
  • TC1 protein
  • TC2 protein
  • TGB protein
  • TGB1 protein
  • THBGB protein
  • THBGB1 protein

Protein level used designations for PPBP

Platelet basic protein , chemokine (C-X-C motif) ligand 7 , platelet basic protein , C-X-C motif chemokine 7 , CXC chemokine ligand 7 , beta-thromboglobulin , connective tissue-activating peptide III , leukocyte-derived growth factor , low-affinity platelet factor IV , macrophage-derived growth factor , neutrophil-activating peptide 2 , neutrophil-activating peptide-2 , small inducible cytokine B7 , small inducible cytokine subfamily B, member 7 , small-inducible cytokine B7 , thrombocidin 1 , thrombocidin 2 , thromboglobulin, beta-1 , neutrophil activating peptide-2 , PBP

GENE ID SPECIES
100196194 Salmo salar
57349 Mus musculus
5473 Homo sapiens
246358 Rattus norvegicus
396870 Sus scrofa
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