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Binds to the C-terminal propeptide of types I and II procollagens and may enhance the cleavage of that propeptide by BMP1 (By similarity).. Additionally we are shipping PCOLCE2 Antibodies (38) and PCOLCE2 Kits (4) and many more products for this protein.
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Procollagen C-endopeptidase protein 2, atherosclerosis and HDL (show HSD11B1 Proteins) cholesteryl ester catabolism. [Review]
Assignment of Pcolce2 gene, which encodes procollagen C-proteinase enhancer protein 2, to hum (show PCOLCE Proteins)an chromosome 3q23.
PCPE2 is shown to be a glycoprotein that differs markedly in the nature of its glycosylation from that of PCPE1 (show PCOLCE Proteins)
Data indicate that PCPE2 accelerates the proteolytic processing of pro-apolipoprotein (apo) AI (show APOA1 Proteins) by enhancing the cleavage of the hexapeptide extension present at the N terminus of apoAI.
PCPE2 was shown to enhance SR-BI (show SCARB1 Proteins) function by increasing the rate of HDL (show HSD11B1 Proteins)-associated cholesteryl ester uptake, possibly by optimizing SR-BI (show SCARB1 Proteins) localization and/or conformation.
It was shown that PCOLCE2 is required for efficient procollagen processing and deposition of fibrillar collagen in the pressure-overloaded myocardium.
the role of the PCPE2 protein in an in vivo model
Assignment of the mouse Pcolce2 gene, which encodes procollagen C-proteinase enhancer protein (show PCOLCE Proteins) 2, to chromosome 9.
Binds to the C-terminal propeptide of types I and II procollagens and may enhance the cleavage of that propeptide by BMP1 (By similarity).
procollagen C-proteinase enhancer 2
, procollagen COOH-terminal proteinase enhancer 2