You are viewing an incomplete version of our website. Please click to reload the website as full version.

Proteasome (Prosome, Macropain) Activator Subunit 2 (PA28 Beta) Proteins (PSME2)

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. Additionally we are shipping Proteasome (Prosome, Macropain) Activator Subunit 2 (PA28 Beta) Antibodies (94) and Proteasome (Prosome, Macropain) Activator Subunit 2 (PA28 Beta) Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat PSME2 PSME2 29614 Q63798
PSME2 5721 Q9UL46
PSME2 19188 P97372
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top Proteasome (Prosome, Macropain) Activator Subunit 2 (PA28 Beta) Proteins at antibodies-online.com

Showing 10 out of 13 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 7 to 8 Days
$407.00
Details
HOST_Escherichia coli (E. coli) Human GST tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Please inquire GST tag Proteasome (Prosome, Macropain) Activator Subunit 2 (PA28 Beta) (PSME2) (AA 2-239), (full length) protein (GST tag) 1 mg Log in to see 56 to 66 Days
$1,842.50
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 2 to 3 Days
$165.00
Details
Yeast Wild boar His tag   1 mg Log in to see 56 to 66 Days
$2,603.33
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,603.33
Details
HOST_Escherichia coli (E. coli) Human His tag   0.1 mg Log in to see 2 to 3 Days
$343.75
Details

PSME2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Top referenced Proteasome (Prosome, Macropain) Activator Subunit 2 (PA28 Beta) Proteins

  1. Human PSME2 Protein expressed in Escherichia coli (E. coli) - ABIN667979 : Fabunmi, Wigley, Thomas, DeMartino: Interferon gamma regulates accumulation of the proteasome activator PA28 and immunoproteasomes at nuclear PML bodies. in Journal of cell science 2001 (PubMed)
    Show all 2 references for ABIN667979

More Proteins for Proteasome (Prosome, Macropain) Activator Subunit 2 (PA28 Beta) (PSME2) Interaction Partners

Human Proteasome (Prosome, Macropain) Activator Subunit 2 (PA28 Beta) (PSME2) interaction partners

  1. Naa10p suppresses 28S proteasome activity through interaction with PA28beta.

  2. knockdown of PA28beta could enhance tumor invasion and metastasis, at least in part, through up-regulation of CLIC1 (show CLIC1 Proteins) in gastric adenocarcinoma

  3. PA28 selectively up-regulates the presentation of viral MHC class I epitopes and that down regulation PA28 in tumor cells results in impaired presentation of a human TRP2 (show DCT Proteins) tumor antigen.

  4. Impaired expression of proteasome subunits is involved in the loss of HLA class I (show MICA Proteins) expression in human colon cancer cells.

Mouse (Murine) Proteasome (Prosome, Macropain) Activator Subunit 2 (PA28 Beta) (PSME2) interaction partners

  1. Nrf2 (show NFE2L2 Proteins)-dependent induction of proteasome and Pa28alphabeta regulator are required for adaptation to oxidative stress.

  2. demonstrate that PA28 and the proteasome immunosubunits use fundamentally different mechanisms to enhance the supply of MHC class I-binding peptides

  3. the processing of antigens is regulated by two distinct pathways, one requiring PA28 and the other hsp90 (show HSP90 Proteins)

  4. An alternative splice pattern of the Psme2 (PA28b) gene, which encodes the beta subunit (show POLG Proteins) of the proteasome activator PA28, is characterized.

Proteasome (Prosome, Macropain) Activator Subunit 2 (PA28 Beta) (PSME2) Protein Profile

Protein Summary

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits\; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) of the 11S regulator have been identified. This gene encodes the beta subunit of the 11S regulator, one of the two 11S subunits that is induced by gamma-interferon. Three beta and three alpha subunits combine to form a heterohexameric ring. Six pseudogenes have been identified on chromosomes 4, 5, 8, 10 and 13.

Gene names and symbols associated with PSME2

  • proteasome activator subunit 2 (psme2)
  • proteasome (prosome, macropain) activator subunit 2 (PA28 beta) (PSME2)
  • proteasome (prosome, macropain) activator subunit 2 (Psme2)
  • proteasome (prosome, macropain) activator subunit 2 (PA28 beta) (Psme2)
  • AA589371 protein
  • AI788882 protein
  • PA28b protein
  • PA28beta protein
  • REGbeta protein
  • unp309 protein

Protein level used designations for PSME2

proteasome activator complex subunit 2 , pA28-b , proteasome activator subunit 2 , 11S regulator complex subunit beta , PA28b , PA28beta , REG-beta , activator of multicatalytic protease subunit 2 , protease (prosome, macropain) 28 subunit, beta , proteasome (prosome, macropain) 28 subunit, beta , proteasome activator 28 subunit beta , 11S regulator complex beta subunit , MCP activator, 31-kD subunit , cell migration-inducing protein 22 , proteasome activator 28-beta , proteasome activator hPA28 subunit beta , PA28 beta subunit , proteasome activator 28 beta subunit

GENE ID SPECIES
30647 Danio rerio
744802 Pan troglodytes
100196625 Salmo salar
29614 Rattus norvegicus
5721 Homo sapiens
480258 Canis lupus familiaris
19188 Mus musculus
509857 Bos taurus
397522 Sus scrofa
Selected quality suppliers for Proteasome (Prosome, Macropain) Activator Subunit 2 (PA28 Beta) Proteins (PSME2)
Did you look for something else?