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Proteasome (Prosome, Macropain) Subunit, beta Type, 5 Proteins (PSMB5)

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. Additionally we are shipping Proteasome (Prosome, Macropain) Subunit, beta Type, 5 Antibodies (50) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PSMB5 19173 O55234
PSMB5 29425 P28075
PSMB5 5693 P28074
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Top Proteasome (Prosome, Macropain) Subunit, beta Type, 5 Proteins at antibodies-online.com

Showing 10 out of 17 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 7 to 8 Days
$407.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Chicken His tag   1 mg Log in to see 56 to 66 Days
$2,489.67
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,498.83
Details
Yeast Pongo abelii His tag   1 mg Log in to see 56 to 66 Days
$2,498.83
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,498.83
Details
Yeast REACT_Spinach His tag   1 mg Log in to see 56 to 66 Days
$2,539.17
Details
HOST_Escherichia coli (E. coli) Human His tag   1 mg Log in to see 3 to 4 Days
$5,769.50
Details

PSMB5 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Rat (Rattus)

Human , ,
,

Top referenced Proteasome (Prosome, Macropain) Subunit, beta Type, 5 Proteins

  1. Human PSMB5 Protein expressed in Escherichia coli (E. coli) - ABIN667858 : Wenzel, Baumeister: Conformational constraints in protein degradation by the 20S proteasome. in Nature structural biology 1995 (PubMed)
    Show all 2 references for ABIN667858

More Proteins for Proteasome (Prosome, Macropain) Subunit, beta Type, 5 (PSMB5) Interaction Partners

Mouse (Murine) Proteasome (Prosome, Macropain) Subunit, beta Type, 5 (PSMB5) interaction partners

  1. The role of the ubiquitin-proteasome system in pressure overloaded hearts andheart failure.

  2. Probeta5 predominantly promotes integration into LMP2 (show PSMB9 Proteins)/MECL-1 (show PSMB10 Proteins)-containing precursors in IFNgamma-stimulated, LMP7 (show PSMB8 Proteins)-deficient cells and infected LMP7 (show PSMB8 Proteins)-deficient mice.

  3. Data demonstrate that TNF-alpha (show TNF Proteins) expression is primarily dependent on both the chymotrypsin-and the trypsin-like activities of X, Y, Z subunits (PSMB5, PSMB6 (show PSMB6 Proteins), PSMB7 (show PSMB7 Proteins)) of the proteasome.

Human Proteasome (Prosome, Macropain) Subunit, beta Type, 5 (PSMB5) interaction partners

  1. Data indicate that proteasomal subunit X PSMB5 is a target of signal transducer and activator of transcription 3 (STAT3 (show STAT3 Proteins)).

  2. Nuclear MB1 expression was an independent predictor of worse survival in ovarian cancer.

  3. critical role of PSMB5 in 20S proteasome (show PSMA5 Proteins)-mediated protection against replicative senescence, pointing to a possible strategy for maintaining the integrity of culture-expanded bone marrow stromal cells by manipulating the expression of PSMB5

  4. Data indicate that treatment-emergent resistance to single-agent bortezomib was independent of variants in the proteasome genes PSMB1 (show PSMB1 Proteins), PSMB5, PSMB6 (show PSMB6 Proteins), PSMB8 (show PSMB8 Proteins), PSMB9 (show PSMB9 Proteins), and PSMB10 (show PSMB10 Proteins).

  5. Letter/Case Reports: proteasome subunit beta5t is expressed in cervical ectopic thymoma.

  6. PSMB5 overexpression is associated with Bortezomib resistance in myeloma.

  7. No mutations or differences in PSMB5 mRNA expression were seen before bortezomib treatment in 3 multiple myeloma patients, but after treatment, 1 patient showed PSMB5 upregulation associated with bortezomib resistance.

  8. CDK5 (show CDK5 Proteins) regulation of proteasome subunit PSMB5 was identified as a probable route to antineoplastic drug sensitization.

  9. Expression of mutated PSMB5 was associated with the prevention of the accumulation of unfolded proteins

  10. interaction of TAP1 and TAP2 and P-glycoprotein with proteasome subunits beta-5 and beta-5i suggest direct targeting of antigenic peptides to the ER via a TAP-proteasome association and a possible role for P-glycoprotein

Proteasome (Prosome, Macropain) Subunit, beta Type, 5 (PSMB5) Protein Profile

Protein Summary

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits\; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. This catalytic subunit is not present in the immunoproteasome and is replaced by catalytic subunit 3i (proteasome beta 8 subunit). Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with PSMB5

  • proteasome (prosome, macropain) subunit, beta type, 5 (PSMB5)
  • proteasome (prosome, macropain) subunit, beta type, 5 (psmb5)
  • proteasome (prosome, macropain) subunit, beta type 5 (Psmb5)
  • etID309919.2 protein
  • fb59c07 protein
  • LMPX protein
  • MB1 protein
  • si:zc14a17.13 protein
  • wu:fb59c07 protein
  • x protein
  • zgc:86820 protein

Protein level used designations for PSMB5

proteasome subunit beta type 5 , proteasome subunit beta type-5 , proteasome (prosome, macropain) subunit, beta type, 5 , macropain epsilon chain , multicatalytic endopeptidase complex epsilon chain , proteasome beta type subunit 5 , proteasome chain 6 , proteasome epsilon chain , proteasome subunit X , proteasome beta 5 subunit , PSX large multifunctional protease X , proteasome catalytic subunit 3 , proteasome subunit MB1 , proteasome subunit, beta type, 5 , macropain chain 1 , multicatalytic endopeptidase complex chain 1 , proteasome C1 subunit , proteasome chain 1 , proteasome subunit C1

GENE ID SPECIES
677719 Macaca mulatta
100379732 Xenopus (Silurana) tropicalis
19173 Mus musculus
29425 Rattus norvegicus
5693 Homo sapiens
534640 Bos taurus
30387 Danio rerio
100127332 Xenopus laevis
396003 Gallus gallus
480246 Canis lupus familiaris
100173015 Pongo abelii
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