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anti-Protein-O-Mannosyltransferase 1 (POMT1) Antibodies

The protein encoded by POMT1 is an O-mannosyltransferase that requires interaction with the product of the POMT2 gene for enzymatic function. Additionally we are shipping Protein-O-Mannosyltransferase 1 Kits (4) and Protein-O-Mannosyltransferase 1 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
POMT1 10585 Q9Y6A1
POMT1 99011 Q8R2R1
POMT1 84430 Q99PR0
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Top anti-Protein-O-Mannosyltransferase 1 Antibodies at antibodies-online.com

Showing 10 out of 44 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, FACS, IHC (p), WB Flow cytometric analysis of U251 cells using POMT1 Antibody (C-term) Cat.-No AP53389PU-N (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue reacted with POMT1 Antibody (C-term) followed which was peroxidase conjugated to the secondary antibody and followed by DAB staining. This data demonstrates the use of POMT1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-POMT1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB POMT1 Antibody (C-term) (ABIN656314) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated WB POMT1 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Rabbit APC FACS, IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated FACS, IHC, WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Rabbit Biotin IHC (p), WB   100 μL Log in to see 14 to 21 Days
$357.50
Details

POMT1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Protein-O-Mannosyltransferase 1 Antibodies

  1. Human Polyclonal POMT1 Primary Antibody for EIA, FACS - ABIN954244 : Manya, Akasaka-Manya, Nakajima, Kawakita, Endo: Role of N-glycans in maintaining the activity of protein O-mannosyltransferases POMT1 and POMT2. in Journal of biochemistry 2010 (PubMed)
    Show all 2 references for ABIN954244

More Antibodies against Protein-O-Mannosyltransferase 1 Interaction Partners

Human Protein-O-Mannosyltransferase 1 (POMT1) interaction partners

  1. Inhibition of POMT1/2 in human mesencyhmal stem cells , resulted in complete abolishment of chondrogenesis and alterations of adipogenic and osteogenic potential together with a lethal effect during myogenic induction.

  2. Three patients with heterozygous POMT1 mutations showed left ventricular (LV) dilation and/or decrease in myocardial contractile force.

  3. the effects of replacing Arg(64), Glu (show DCTN1 Antibodies)(78) and Arg(138)residues in human POMT1 and POMT2 (show POMT2 Antibodies) with Ala on complex formation and enzymatic activity were studied.

  4. the function of the gene products is only known for POMT1, POMT2 (show POMT2 Antibodies), and POMGnT1 (show POMGNT1 Antibodies), all responsible for the O-mannosylglycan biosynthesis

  5. the N-glycosylation of POMT1 and POMT2 (show POMT2 Antibodies) is required for maintaining the conformation as well as the activity of the POMT1-POMT2 (show POMT2 Antibodies) complex.

  6. Mutations in the O-mannosyltransferase gene POMT1 give rise to the severe neuronal migration disorder Walker-Warburg syndrome

  7. Extracellular matrix and nuclear abnormalities in skeletal muscle of a patient with Walker-Warburg syndrome caused by POMT1 mutation.

  8. active enzyme complex of POMT1 and POMT2 (show POMT2 Antibodies) suggests that the regulation of protein O-mannosylation is complex and appears to be required for normal structure and function of alpha-dystroglycan in muscle and brain

  9. The authors report on a patient with Walker-Warburg syndrome and a novel POMT1 mutation. The patient expressed alpha-dystroglycan core protein, but fully glycosylated alpha-DG antibody epitopes were absent, associated with loss of laminin-binding activity

  10. Results indicate that mutations in the protein O-mannosyltransferase 1 gene result in a defect of protein O-mannosylation in Walker-Warburg syndrome patients.

Mouse (Murine) Protein-O-Mannosyltransferase 1 (POMT1) interaction partners

  1. during embryogenesis, Pomt1 is expressed in the neural tube, the developing eye, and the mesenchyme; targeted deletion of Pomt1 results in early embryonic lethality due to defects in the assembly of Reichert's membrane

Protein-O-Mannosyltransferase 1 (POMT1) Antigen Profile

Protein Summary

The protein encoded by this gene is an O-mannosyltransferase that requires interaction with the product of the POMT2 gene for enzymatic function. The encoded protein is found in the membrane of the endoplasmic reticulum. Defects in this gene are a cause of Walker-Warburg syndrome (WWS) and limb-girdle muscular dystrophy type 2K (LGMD2K). Several transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with POMT1

  • protein-O-mannosyltransferase 1 (POMT1) antibody
  • protein-O-mannosyltransferase 1 (Pomt1) antibody
  • AI505244 antibody
  • LGMD2K antibody
  • MDDGA1 antibody
  • MDDGB1 antibody
  • MDDGC1 antibody
  • RT antibody

Protein level used designations for POMT1

dolichyl-phosphate-mannose--protein mannosyltransferase 1 , dolichyl-phosphate-mannose-protein mannosyltransferase , protein O-mannosyl-transferase 1 , protein O-mannosyltransferase 1

GENE ID SPECIES
10585 Homo sapiens
617609 Bos taurus
99011 Mus musculus
84430 Rattus norvegicus
608039 Canis lupus familiaris
100525803 Sus scrofa
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