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binds GTP but does not display intrinsic GTPase activity. Additionally we are shipping and many more products for this protein.
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Genetic ablation of RAB7L1 in SH-SY5Y cells recapitulated the findings in amyotrophic lateral sclerosis and frontotemporal dementia fibroblasts and induced pluripotent stem cell neurons
This study showed that the significant differences in genotypic and allelic frequencies of RAB7L1 promoter polymorphism between patients and controls.
Our study provides strong support for the susceptibility role of RAB7L1/NUCKS1 rs823118 and MCCC1 rs12637471 in sporadic Parkinson's disease in a Han Chinese population
Rab29 is a regulator of receptor recycling and this GTPase (show RACGAP1 Antibodies) is a shared participant in immune synapse and primary cilium assembly.
rs1572931 decreases the risk for Parkinson's disease but not for amyotrophic lateral sclerosis (ALS (show IGFALS Antibodies)) and multiple system atrophy(MSA (show TPO Antibodies)) in the Chinese population. However, the polymorphism is unlikely to be a common cause of sporadic ALS (show IGFALS Antibodies) and MSA (show TPO Antibodies) in the Chinese population
Results suggest that Rab (show HRB Antibodies) protein Rab29 is essential for the integrity of the trans-Golgi network (TGN (show TG Antibodies)) and participates in the retrograde trafficking of mannose-6-phosphate receptor (M6PR (show M6PR Antibodies)).
RAB7L1 is a binding partners of LRRK2 (show LRRK2 Antibodies), a candidate genes for risk for sporadic Parkinson disease, and part of a complex that promotes clearance of Golgi-derived vesicles through the autophagy-lysosome system.
This study confirmed the associations of RAB7L1 with parkinson disease susceptibility and fail to show significant associations of alzheimer disease genome-wide association study (GWAS) top hits with PD susceptibility in a Korean population.
This study demonistrated that RAB7L1 interacts with LRRK2 (show LRRK2 Antibodies) to modify intraneuronal protein sorting and Parkinson's disease risk.
Direct DNA sequencing of the RAB7L1 and SLC41A1 (show SLC41A1 Antibodies) genes within the PARK16 locus in 205 Chinese Parkinson's disease patients shows no significant difference with controls.
binds GTP but does not display intrinsic GTPase activity
RAB7, member RAS oncogene family-like 1
, rab-7-like protein 1
, ras-related protein Rab-7L1
, Ras-related GTP-binding protein Rab29
, ras-related protein Rab-29