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Reelin Proteins (RELN)

RELN encodes a large secreted extracellular matrix protein thought to control cell-cell interactions critical for cell positioning and neuronal migration during brain development. Additionally we are shipping Reelin Antibodies (54) and Reelin Kits (29) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
RELN 19699 Q60841
RELN 5649 P78509
RELN 24718 P58751
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Top Reelin Proteins at antibodies-online.com

Showing 9 out of 18 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag,S tag 100 μg Log in to see 11 to 13 Days
$785.40
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$721.60
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,025.83
Details
HOST_Escherichia coli (E. coli) Human His tag   50 μg Log in to see 11 Days
$341.00
Details
Yeast Human His tag   50 μg Log in to see 8 to 11 Days
$341.00
Details
HOST_Escherichia coli (E. coli) Rat His tag,S tag   100 μg Log in to see 11 to 13 Days
$668.80
Details
HOST_Escherichia coli (E. coli) Rat Un-conjugated   100 μg Log in to see 9 to 16 Days
$735.63
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   100 μg Log in to see 9 to 16 Days
$831.88
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 16 to 21 Days
$285.71
Details

RELN Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
,
Rat (Rattus)

More Proteins for Reelin (RELN) Interaction Partners

Zebrafish Reelin (RELN) interaction partners

  1. Developmental gene expression pattern of reelin, dab1 (show DAB1 Proteins), vldlr (show VLDLR Proteins), and apoer2 (show LRP8 Proteins) in the central nervous system of zebrafish was compared, and their remarkable expression was detected in the developing laminar structures and also non-laminated structures.

Mouse (Murine) Reelin (RELN) interaction partners

  1. These findings suggest that circulating Reelin promotes atherosclerosis by increasing vascular inflammation, and that reducing or inhibiting circulating Reelin may present a novel approach for the prevention of cardiovascular disease.

  2. A new transgenic mouse model demonstrates that Reelin is a molecule which is critical for proper cortical development.

  3. androgenic hormones can influence cerebral reelin demethylation

  4. data suggest Kdm5b (show KDM5B Proteins) negatively regulates neurogenesis and represses reelin in neural stem cells from the adult subventricular zone.

  5. reveals a novel function for Reelin/ApoER2 (show LRP8 Proteins) in peripheral nervous system, inducing cell migration of Schwann cells, a process relevant for peripheral nervous system development and regeneration

  6. Reelin thus plays a role in restraining RAS and PI3-kinase (show PIK3CA Proteins) promotion of cell motility and potentially tumour metastasis.

  7. meprin alpha (show MEP1A Proteins) and meprin beta (show MEP1B Proteins) join the modulators of Reelin signalling as they cleave Reelin at a specific site and are upregulated under specific pathological conditions.

  8. reelin and cofilin (show CFL1 Proteins) cooperate in controlling cytoskeletal dynamics during neuronal migration.

  9. Results suggest that Reelin induces branching of the leading processes of migrating neurons and that of basal processes of radial glial cells when they arrive at the Reelin-containing marginal zone.

  10. Results revealed that lack of functional reelin does not simply invert, but highly disorganize visual cortical layers, resulting in a massive intermingling of cells with different laminar fates.

Human Reelin (RELN) interaction partners

  1. common variants of GABRG2 (show GABRG2 Proteins), RELN and NRG3 (show NRG3 Proteins) and the GABRG2 (show GABRG2 Proteins)-RELN-PTCH1 (show PTCH1 Proteins) interaction networks might confer altered susceptibility to Hirschsprung disease.

  2. RELN is mapped at 7q22, which had been identified as a candidate region for autism by early genetic linkage study.

  3. reelin promotes multiple myeloma cell adhesion, survival, and drug resistance via activation of integrin alpha5beta1.

  4. These findings suggest that circulating Reelin promotes atherosclerosis by increasing vascular inflammation, and that reducing or inhibiting circulating Reelin may present a novel approach for the prevention of cardiovascular disease.

  5. Reelin thus plays a role in restraining RAS and PI3-kinase (show PIK3CA Proteins) promotion of cell motility and potentially tumour metastasis.

  6. Among men, but not in women certain genotypes of the RELN gene were significantly associated with the susceptibility to Alzheimer's disease.

  7. Report demonstrated that the reelin subregion R5-6 consisting of 747 amino acids in the 5th and 6th repeats was sufficient for apoER2 (show LRP8 Proteins) and VLDLR (show VLDLR Proteins) binding, and inhibiting lipoprotein-induced cholesterol accumulation in macrophages.

  8. The features of reelin expression in the brain of fetuses and newborns at 22-40 weeks' gestation with internal HC should be considered as morphological differential and diagnostic criteria for the disease in relation to its etiology.

  9. Study shows that early neural cells transiently express Reelin at the time they leave the presumptive olfactory/vomeronasal epithelium and that Dab 1 (show DAB1 Proteins) is present in the migratory cell mass and in the presumptive ensheathing cells in the absence of reelin.

  10. the reelin protein blood concentration might be a relevant signal with respect to the pathophysiology of schizophrenia.

Pig (Porcine) Reelin (RELN) interaction partners

  1. A peak in Reelin mRNA and protein expression is present in the pig embryonic brain during the period of major neurogenesis and neuronal migration.

Reelin (RELN) Protein Profile

Protein Summary

This gene encodes a large secreted extracellular matrix protein thought to control cell-cell interactions critical for cell positioning and neuronal migration during brain development. This protein may be involved in schizophrenia, autism, bipolar disorder, major depression and in migration defects associated with temporal lobe epilepsy. Mutations of this gene are associated with autosomal recessive lissencephaly with cerebellar hypoplasia. Two transcript variants encoding distinct isoforms have been identified for this gene. Other transcript variants have been described but their full length nature has not been determined.

Gene names and symbols associated with Reelin Proteins (RELN)

  • reelin (RELN)
  • reelin (reln)
  • reelin (Reln)
  • reelin-like (RELN)
  • LIS2 protein
  • MGC172539 protein
  • PRO1598 protein
  • Reelen protein
  • reeler protein
  • RELN protein
  • Rl protein

Protein level used designations for Reelin Proteins (RELN)

reelin , reelin-like , extracellular matrix serine protease , reelin, extracellular

GENE ID SPECIES
100058621 Equus caballus
260303 Danio rerio
398547 Xenopus laevis
463635 Pan troglodytes
579060 Strongylocentrotus purpuratus
696372 Macaca mulatta
786373 Bos taurus
100013879 Monodelphis domestica
100049232 Oryzias latipes
100192371 Xenopus (Silurana) tropicalis
100403212 Callithrix jacchus
100480458 Ailuropoda melanoleuca
100552788 Anolis carolinensis
100593340 Nomascus leucogenys
19699 Mus musculus
5649 Homo sapiens
24718 Rattus norvegicus
427850 Gallus gallus
483273 Canis lupus familiaris
100127480 Sus scrofa
100723362 Cavia porcellus
281450 Bos taurus
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