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Regulating Synaptic Membrane Exocytosis 2 Proteins (RIMS2)

synaptic protein important for normal neurotransmitter release\; binds Rab3a [RGD, Feb 2006].. Additionally we are shipping Regulating Synaptic Membrane Exocytosis 2 Antibodies (68) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
RIMS2 9699 Q9UQ26
RIMS2 116838 Q9EQZ7
Rat RIMS2 RIMS2 116839 Q9JIS1
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Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

RIMS2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Regulating Synaptic Membrane Exocytosis 2 (RIMS2) Interaction Partners

Human Regulating Synaptic Membrane Exocytosis 2 (RIMS2) interaction partners

  1. Here, we report that, like Rab3A, RIM and Munc13 are present in human sperm and that they play a functional role in acrosomal exocytosis before the acrosomal calcium efflux

  2. These data suggest that RIM2beta contributes to the stabilization of Ca(v)1.3 (show CACNA1D Proteins) gating kinetics in immature cochlear inner hair cells.

  3. Western blot analysis shows increased RIMS2 protein expression in the amygdala in schizophrenia.

  4. tick-borne encephalitis virus -NS5 (show RAF1 Proteins) has high affinity to regulating synaptic membrane exocytosis-2 (RIMS2) and Scribble, whereas DENV-NS5 (show RAF1 Proteins) binds primarily to the tight junction protein (show OCLN Proteins) zonula occludens-1 (ZO-1 (show TJP1 Proteins))

Mouse (Murine) Regulating Synaptic Membrane Exocytosis 2 (RIMS2) interaction partners

  1. The function of RIM1/2 at rod ribbons is to enhance Cav1.4 (show CACNA1F Proteins) channel activity, possibly through direct or indirect modulation of the channel.

  2. RIM2alpha and RIM2beta promote a large complement of synaptic CaV1.3 (show CACNA1D Proteins) Ca(2 (show CA2 Proteins)+) channels at inner hair cell presynaptic active zones and are required for normal hearing.

  3. Experiments with single Rim 1/2 gene inactivation at the large calyx of Held synapse show largely overlapping roles of the two major Rim genes in vesicle priming/docking

  4. Data suggest that RIM1/2 proteins co-ordinately regulate key functions for fast transmitter release, enabling a high presynaptic Ca(2 (show CA2 Proteins))+ channel density and vesicle docking at the active zone.

  5. Rim2alpha determines docking and priming states in insulin granule exocytosis depending on its interacting partner, Rab3A or Munc13-1, respectively.

  6. Alternative splicing in the Rab (show HRB Proteins)-binding domain of Rim2 (show AP3B1 Proteins) regulates Rab3A (show RAB3A Proteins) binding activity.

  7. These data demonstrate that alpha-RIMs are not essential for synapse formation or synaptic exocytosis, but are required for normal Ca(2 (show CA2 Proteins)+)-triggering of exocytosis.

  8. Cyclic AMP (show TMPRSS5 Proteins) rescue of priming defects caused by Munc13-1 deficiency signaling pathways requires downstream Munc13-1-Rim2 (show AP3B1 Proteins) interaction.

Regulating Synaptic Membrane Exocytosis 2 (RIMS2) Protein Profile

Protein Summary

synaptic protein important for normal neurotransmitter release\; binds Rab3a

Gene names and symbols associated with RIMS2

  • regulating synaptic membrane exocytosis 2 (RIMS2)
  • regulating synaptic membrane exocytosis 2 (Rims2)
  • 2810036I15Rik protein
  • AW048769 protein
  • MGC159469 protein
  • mKIAA0751 protein
  • Nim2 protein
  • OBOE protein
  • Rab3ip2 protein
  • RAB3IP3 protein
  • Rim2 protein
  • Rim2(+4A) protein
  • Rim2(+40A) protein
  • Rim2(+44A) protein
  • RIMS2 protein
  • Serg2 protein
  • Syt3-rs protein

Protein level used designations for RIMS2

regulating synaptic membrane exocytosis 2 , RAB3 interacting protein 3 , RIM 2 , non-small cell lung cancer RimL3a protein , non-small cell lung cancer RimL3c protein , nuclear protein , rab-3-interacting molecule 2 , rab-3-interacting protein 3 , rab3-interacting molecule 2 , regulating synaptic membrane exocytosis protein 2 , Rab3 interacting protein 1 , Rab3 interacting protein 2 , rab-3-interacting protein 2 , rab3-interacting protein 2 , synaptic exocytosis regulator 2 , synaptotagmin 3, related sequence

GENE ID SPECIES
420264 Gallus gallus
535674 Bos taurus
9699 Homo sapiens
116838 Mus musculus
116839 Rattus norvegicus
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