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Rhomboid, Veinlet-Like 2 (Drosophila) Proteins (RHBDL2)

The protein encoded by RHBDL2 is a member of the rhomboid family of integral membrane proteins. Additionally we are shipping RHBDL2 Antibodies (22) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
RHBDL2 54933 Q9NX52
RHBDL2 230726 A2AGA4
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Top RHBDL2 Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 16 to 21 Days
$314.29
Details

RHBDL2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Rhomboid, Veinlet-Like 2 (Drosophila) (RHBDL2) Interaction Partners

Human Rhomboid, Veinlet-Like 2 (Drosophila) (RHBDL2) interaction partners

  1. Thrombomodulin and RHBDL2 are upr (show THBD Proteins)egulated in human HaCaT cells stimulated by scratch wounds; furthermore, increased solulbe thrombomodulin was found (show THBD Proteins) in culture medium.

  2. RHBDL2 cleaves epidermal growth factor (show EGF Proteins) just outside its transmembrane domain, thereby facilitating its secretion and triggering activation of the epidermal growth factor receptor (show EGFR Proteins).

  3. Substrate specificity of RHBDL2 intramembrane protease is governed by helix-breaking residues in the transmembrane domain.

  4. Here, the authors show that RHBDL2 is produced as a proenzyme and that the processing of RHBDL2 is required for its cellular protease activity.

  5. The encoded protein is thought to release soluble growth factors by proteolytic cleavage of certain membrane-bound substrates, including ephrin B2 (show EFNB2 Proteins) and ephrin B3 (show EFNB3 Proteins).

Mouse (Murine) Rhomboid, Veinlet-Like 2 (Drosophila) (RHBDL2) interaction partners

  1. RHBDL2 and soluble thrombomodulin (show THBD Proteins) were upregulated in ex vivo tissue culture of injured mouse skin. 3,4-Dichloroisocoumarin inhibited thrombomodulin (show THBD Proteins) production and wound healing; this was reversed by recombinant thrombomodulin (show THBD Proteins) in mice.

RHBDL2 Protein Profile

Protein Summary

The protein encoded by this gene is a member of the rhomboid family of integral membrane proteins. This family contains proteins that are related to Drosophila rhomboid protein. Members of this family are found in both prokaryotes and eukaryotes and are thought to function as intramembrane serine proteases. The encoded protein is thought to release soluble growth factors by proteolytic cleavage of certain membrane-bound substrates, including ephrin B2 and ephrin B3.

Gene names and symbols associated with RHBDL2

  • rhomboid, veinlet-like 2 (Drosophila) (RHBDL2)
  • rhomboid, veinlet-like 2 (Drosophila) (Rhbdl2)
  • 9130416B15 protein
  • RRP2 protein

Protein level used designations for RHBDL2

rhomboid (veinlet, Drosophila)-like 2 , rhomboid protease 2 , rhomboid-like protein 2 , rhomboid-related protein 2

GENE ID SPECIES
54933 Homo sapiens
482466 Canis lupus familiaris
230726 Mus musculus
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