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Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Additionally we are shipping RPS14 Proteins (32) and RPS14 Kits (30) and many more products for this protein.
Showing 10 out of 69 products:
Human Polyclonal RPS14 Primary Antibody for ELISA, WB - ABIN562728
Ebert, Pretz, Bosco, Chang, Tamayo, Galili, Raza, Root, Attar, Ellis, Golub: Identification of RPS14 as a 5q- syndrome gene by RNA interference screen. in Nature 2008
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Human Polyclonal RPS14 Primary Antibody for EIA, WB - ABIN954612
Oliva, Cuzzola, Nobile, Ronco, DErrigo, Laganà, Morabito, Galimberti, Cortelezzi, Aloe Spiriti, Specchia, Poloni, Breccia, Ghio, Finelli, Iacopino, Alimena, Latagliata: Changes in RPS14 expression levels during lenalidomide treatment in Low- and Intermediate-1-risk myelodysplastic syndromes with chromosome 5q deletion. in European journal of haematology 2010
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Dog (Canine) Polyclonal RPS14 Primary Antibody for WB - ABIN2778744
Kenmochi, Kawaguchi, Rozen, Davis, Goodman, Hudson, Tanaka, Page: A map of 75 human ribosomal protein genes. in Genome research 1998
ribosomal protein RPS-14 is able to modulate let-7 function in C. elegans
p53 (show TP53 Antibodies) synthesis is affected in zebrafish tumors with ribosomal protein gene mutations
Partial silencing of RPS14 inhibits the proliferation of SKM-1, an acute myeloid leukemia (show BCL11A Antibodies) cell line, and RPS14 negatively regulates p53 (show TP53 Antibodies) activation in SKM-1 cells.
RPS14 stabilized and activated p53 (show TP53 Antibodies) by inhibiting HDM2-mediated p53 (show TP53 Antibodies) polyubiquitination and degradation
Patients with nonclassical Diamond Blackfan anemia and other hypoproliferative anemias may have somatically acquired 5q deletions with RPS14 haploinsufficiency
Data indicate that RPS14 negates c-Myc (show MYC Antibodies) functions by directly inhibiting its transcriptional activity and mediating its mRNA degradation via miRNA.
lower RPS14 predicts prolonged survival and possible response to lenalidomide in lower risk MDS (show PAFAH1B1 Antibodies) patients.
RPS14 and RPS19 (show RPS19 Antibodies) have distinct roles in regulating the MDM2 (show MDM2 Antibodies)-p53 (show TP53 Antibodies) feedback loop in response to ribosomal stress
Loss of RPS14 is associated with 5q-syndrome.
Combined loss of miR (show MLXIP Antibodies)-145 and RPS14 cooperates to alter erythroid-megakaryocytic differentiation in a manner similar to the 5q- syndrome.
Myelodysplactic syndrome patients with an intermediate-1 risk score and low RPS14 expression have a superior median overall survival compared to patients with high RPS14 expression.
p53 (show TP53 Antibodies) accumulates selectively in the erythroid lineage in primary human hematopoietic progenitor cells after expression of shRNAs targeting RPS14, the ribosomal protein gene deleted in the 5q-syndrome, or RPS19 (show RPS19 Antibodies).
Rps14 haploinsufficiency in del(5q) myelodysplastic syndrome is linked to activation of the innate immune system and induction of S100A8 (show S100A8 Antibodies)-S100A9 (show S100A9 Antibodies) expression, leading to a p53 (show TP53 Antibodies)-dependent erythroid differentiation defect.
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S11P family of ribosomal proteins. It is located in the cytoplasm. Transcript variants utilizing alternative transcription initiation sites have been described in the literature. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. In Chinese hamster ovary cells, mutations in this gene can lead to resistance to emetine, a protein synthesis inhibitor. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.
ribosomal protein S14
, 40S ribosomal protein S14
, emetine resistance
, ribosomal protein S14b