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anti-Ring Finger Protein 111 (RNF111) Antibodies

The protein encoded by RNF111 is a nuclear RING-domain containing E3 ubiquitin ligase. Additionally we are shipping RNF111 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
RNF111 93836 Q99ML9
RNF111 54778 Q6ZNA4
RNF111 300813  
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Top anti-RNF111 Antibodies at antibodies-online.com

Showing 10 out of 36 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Mouse Un-conjugated IF, RNAi, ELISA, WB Western blot analysis of RNF111 over-expressed 293 cell line, cotransfected with RNF111 Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1). Blot probed with RNF111 monoclonal antibody (M05), clone 1C4. GAPDH ( 36.1 kDa ) used as specificity and loading control. Western Blot analysis of RNF111 expression in transfected 293T cell line by RNF111 monoclonal antibody (M05), clone 1C4.Lane 1: RNF111 transfected lysate(107.8 KDa).Lane 2: Non-transfected lysate. 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated WB RNF111 Antibody (N-term)  western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the RNF111 antibody detected the RNF111 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated IHC (p), WB Western Blot analysis of RNF111 expression in transfected 293T cell line by RNF111 MaxPab polyclonal antibody.Lane 1: RNF111 transfected lysate(108.35 KDa).Lane 2: Non-transfected lysate. RNF111 MaxPab polyclonal antibody. Western Blot analysis of RNF111 expression in rat brain. 50 μg Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated WB Western blot analysis of RNF111 over-expressed 293 cell line, cotransfected with RNF111 Validated Chimera RNAi used as specificity and loading control. Western Blot analysis of RNF111 expression in transfected 293T cell line by RNF111 monoclonal antibody (M05), clone 1C4. Lane 1: RNF111 transfected lysate(107.8 KDa). Lane 2: Non-transfected lysate. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit PE ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated ELISA, WB   100 μL Log in to see 14 Days
$201.19
Details
Human Rabbit Un-conjugated ELISA, WB   100 μL Log in to see 8 to 10 Days
$478.50
Details
Human Rabbit Un-conjugated IHC, WB   50 μg Log in to see 3 to 4 Days
$473.93
Details

RNF111 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine)


Human , ,
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Rat (Rattus)


Top referenced anti-RNF111 Antibodies

  1. Human Monoclonal RNF111 Primary Antibody for IF, RNAi - ABIN527194 : Levy, Howell, Das, Harkin, Episkopou, Hill: Arkadia activates Smad3/Smad4-dependent transcription by triggering signal-induced SnoN degradation. in Molecular and cellular biology 2007 (PubMed)
    Show all 9 references for ABIN527194

  2. Human Polyclonal RNF111 Primary Antibody for IHC (p), WB - ABIN527193 : Zhou, Drabsch, Dekker, de Vinuesa, Li, Hawinkels, Sheppard, Goumans, Luwor, de Vries, Mesker, Tollenaar, Devilee, Lu, Zhu, Zhang, Dijke: Nuclear receptor NR4A1 promotes breast cancer invasion and metastasis by activating TGF-? signalling. in Nature communications 2014 (PubMed)
    Show all 2 references for ABIN527193

  3. Human Polyclonal RNF111 Primary Antibody for ELISA, WB - ABIN1451235 : Zody, Garber, Sharpe, Young, Rowen, ONeill, Whittaker, Kamal, Chang, Cuomo, Dewar, FitzGerald, Kodira, Madan, Qin, Yang, Abbasi, Abouelleil, Arachchi, Baradarani, Birditt, Bloom, Bloom, Borowsky et al.: Analysis of the DNA sequence and duplication history of human chromosome 15. ... in Nature 2006 (PubMed)

More Antibodies against RNF111 Interaction Partners

Mouse (Murine) Ring Finger Protein 111 (RNF111) interaction partners

  1. Arkadia, but not the C937A (CA) mutant lacking E3 ubiquitin-ligase (show MUL1 Antibodies) activity, induced ubiquitylation and proteasome-dependent degradation of Smad6 (show SMAD6 Antibodies).

  2. Arkadia enhances transforming growth factor-beta signaling responses and supports its tumor-suppressing properties in colorectal cancer.

  3. RB1CC1 (show RB1CC1 Antibodies) thus appears to play a unique role as a modulator of TGF-beta (show TGFB1 Antibodies) signaling by restricting substrate specificity of Arkadia.

  4. Trps1 haploinsufficiency enhances TGF-beta1-induced epithelial-to-mesenchymal transition (EMT) and tubulointerstitial fibrosis by modulating the amount of Smad7 through Arkadia/ubiquitin-mediated degradation.

  5. findings show that Arkadia regulates the levels of expression of c-Ski (show SKI Antibodies) protein (show SKIL Antibodies) in cell-type-dependent fashion, and exhibits a tumour suppressor function by inhibiting tumour cell growth

  6. Axin (show AXIN1 Antibodies) and Arkadia cooperate with each other in promoting Smad7 (show SMAD7 Antibodies) ubiquitination.

  7. Arkadia, a nuclear RING-domain E3 ubiquitin ligase (show MUL1 Antibodies), is essential for a subset of Nodal functions in the embryo

  8. Arkadia induces degradation of SnoN (show SKIL Antibodies) and c-Ski (show SKI Antibodies) in addition to Smad7 (show SMAD7 Antibodies).

  9. These results suggest that Arkadia targets Ski (show SKI Antibodies)-bound, inactive phospho-Smad2 (show SMAD2 Antibodies)/3 to regulate positively Myostatin (show MSTN Antibodies)/TGF-beta (show TGFB1 Antibodies) signaling.

  10. This work presents an efficient method for expression in E. coli and purification of recombinant Arkadia RING finger (show PCGF1 Antibodies) domain as a soluble protein.

Human Ring Finger Protein 111 (RNF111) interaction partners

  1. Results suggest that -459CpG methylation in Sp1 (show PSG1 Antibodies)-binding site of RNF111 promoter transcriptionally decreases RNF111 expression, which inhibits TGF-beta (show TGFB1 Antibodies)/Smad (show SMAD1 Antibodies) signaling associated invasion in NSCLC cells.

  2. Study reports that the monomeric RING domains from the human E3 ligases Arkadia and Ark2C bind directly to free ubiquitin with an affinity comparable to that of other dedicated ubiquitin-binding domains.

  3. These data suggest that RNF111, together with the CRL4(DDB2 (show DDB2 Antibodies)) ubiquitin ligase complex, is responsible for sequential XPC (show XPC Antibodies) ubiquitylation, which regulates the recruitment and release of XPC (show XPC Antibodies) and is crucial for efficient progression of the NER (show NR1H2 Antibodies) reaction.

  4. Arkadia can both promote and inhibit gene expression, indicating that Arkadia's activity in transcriptional control may depend on the epigenetic context, defined by Polycomb (show CBX2 Antibodies) repressive complexes and DNA methylation (show HELLS Antibodies).

  5. Our findings establish RNF111 as a new STUbL that directly links nonproteolytic ubiquitylation and SUMOylation in the DNA damage response.

  6. findings indicate that Arkadia is not critical for regulating tumor growth per se, but is required for the early stages of cancer cell colonization at the sites of metastasis

  7. Arkadia is involved in arsenic-induced degradation of polysumoylated PML (show PML Antibodies) protein.

  8. RNF111-dependent neddylation activates DNA damage-induced ubiquitination

  9. FHL2 (show FHL2 Antibodies) increases the stability of the TGF-beta (show TGFB1 Antibodies) pathway positive regulator Arkadia by inhibiting its ubiquitination and cooperates with Arkadia to activate TGF-beta (show TGFB1 Antibodies) signaling.

  10. We established that ARX (show UBA2 Antibodies) polyA alterations damage the regulation of KDM5C (show KDM5C Antibodies) expression.

RNF111 Antigen Profile

Protein Summary

The protein encoded by this gene is a nuclear RING-domain containing E3 ubiquitin ligase. This protein interacts with the transforming growth factor (TGF) -beta/NODAL signaling pathway by promoting the ubiquitination and proteosomal degradation of negative regulators, like SMAD proteins, and thereby enhances TGF-beta target-gene transcription. As a modulator of the nodal signaling cascade, this gene plays a critical role in the induction of mesoderm during embryonic development. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.

Gene names and symbols associated with RNF111

  • ring finger protein 111 (RNF111) antibody
  • hypothetical LOC702104 (RNF111) antibody
  • ring finger protein 111 (rnf111) antibody
  • ring finger protein 111 (LOC100222518) antibody
  • ring finger protein 111 (LOC100357930) antibody
  • ring finger 111 (Rnf111) antibody
  • ring finger protein 111 (Rnf111) antibody
  • ark antibody
  • Arkadia antibody
  • MGC81253 antibody
  • MGC146379 antibody
  • RNF111 antibody

Protein level used designations for RNF111

E3 ubiquitin-protein ligase Arkadia , arkadia , hypothetical LOC702104 , ring finger protein 111 , e3 ubiquitin-protein ligase Arkadia-like , RING finger protein 111 , Arkadia , ring finger 111

GENE ID SPECIES
540353 Bos taurus
374021 Gallus gallus
478323 Canis lupus familiaris
100155446 Sus scrofa
702104 Macaca mulatta
453477 Pan troglodytes
701953 Macaca mulatta
780266 Xenopus (Silurana) tropicalis
100054463 Equus caballus
100222518 Taeniopygia guttata
100357930 Oryctolagus cuniculus
100475090 Ailuropoda melanoleuca
100543062 Meleagris gallopavo
100555431 Anolis carolinensis
100579843 Nomascus leucogenys
93836 Mus musculus
54778 Homo sapiens
300813 Rattus norvegicus
Selected quality suppliers for anti-RNF111 (RNF111) Antibodies
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