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Ring Finger Protein 144B Proteins (RNF144B)

E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates such as LCMT2, thereby promoting their degradation. Additionally we are shipping Ring Finger Protein 144B Antibodies (99) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
RNF144B 255488 Q7Z419
RNF144B 218215 Q8BKD6
Rat RNF144B RNF144B 364681  
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Top Ring Finger Protein 144B Proteins at antibodies-online.com

Showing 3 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
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HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

RNF144B Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Ring Finger Protein 144B (RNF144B) Interaction Partners

Human Ring Finger Protein 144B (RNF144B) interaction partners

  1. findings substantiate PIR2/Rnf144b as a potentially critical component of epithelial homeostasis, acting downstream of DeltaNp63alpha to regulate cellular levels of p21(WAF1/CIP1 (show CDKN1A Proteins)) and DeltaNp63alpha

  2. PIR2/RNF144B/IBRDC2 regulates the stability of TAp73 and DNp73.

  3. IBRDC2, an IBR-type RING-finger (show PCGF1 Proteins) E3 ubiquitin ligase (show MUL1 Proteins), regulates the levels of Bax (show BAX Proteins) and protects cells from unprompted Bax (show BAX Proteins). activation and cell death.

  4. p53RFP, a p53-inducible RING-finger protein, regulates the stability of p21WAF1.

Mouse (Murine) Ring Finger Protein 144B (RNF144B) interaction partners

  1. PIR2, by being induced by TAp73 and degrading DeltaNp73, differentially regulates TAp73/DeltaNp73 stability.[PIR2]

Ring Finger Protein 144B (RNF144B) Protein Profile

Protein Summary

E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates such as LCMT2, thereby promoting their degradation. Induces apoptosis via a p53/TP53-dependent but caspase-independent mechanism. However, its overexpression also produces a decrease of the ubiquitin-dependent stability of BAX, a pro-apoptotic protein, ultimately leading to protection of cell death\; But, it is not an anti-apoptotic protein per se (By similarity).

Gene names and symbols associated with RNF144B

  • ring finger protein 144B (RNF144B)
  • ring finger protein 144B (Rnf144b)
  • bA528A10.3 protein
  • BC025007 protein
  • E130105P19Rik protein
  • Ibrdc2 protein
  • p53RFP protein
  • Pir2 protein

Protein level used designations for RNF144B

E3 ubiquitin-protein ligase RNF144B , IBR domain containing 2 , IBR domain-containing protein 2 , p53-inducible RING finger protein , ring finger 144B

GENE ID SPECIES
255488 Homo sapiens
218215 Mus musculus
524166 Bos taurus
364681 Rattus norvegicus
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