SGT1, Suppressor of G2 Allele of SKP1 (S. Cerevisiae) Proteins (SUGT1)

SUGT1 is homologous to the yeast gene SGT1, which encodes a protein involved in kinetochore function and required for the G1/S and G2/M transitions. Additionally we are shipping SGT1, Suppressor of G2 Allele of SKP1 (S. Cerevisiae) Antibodies (67) and SGT1, Suppressor of G2 Allele of SKP1 (S. Cerevisiae) Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SUGT1 10910 Q9Y2Z0
SUGT1 67955 Q9CX34
SUGT1 290408 B0BN85
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Top SGT1, Suppressor of G2 Allele of SKP1 (S. Cerevisiae) Proteins at antibodies-online.com

Showing 8 out of 12 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
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Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
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HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 15 to 19 Days
$319.00
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HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
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HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
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Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$2,905.83
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Yeast Cow His tag   1 mg Log in to see 60 to 71 Days
$2,911.33
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Human Un-conjugated   5 μg Log in to see 6 Days
$168.54
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SUGT1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Mouse (Murine)

Rat (Rattus)

More Proteins for SGT1, Suppressor of G2 Allele of SKP1 (S. Cerevisiae) (SUGT1) Interaction Partners

Human SGT1, Suppressor of G2 Allele of SKP1 (S. Cerevisiae) (SUGT1) interaction partners

  1. Data suggest that PHLPP1 plays an important role in assembly of kinetochores by counteracting RNF41 (show RNF41 Proteins)-mediated SGT1 degradation. (PHLPP1 = PH domain and leucine rich repeat protein phosphatase 1; RNF41 (show RNF41 Proteins) = ring finger protein 41 (show RNF41 Proteins); SGT1 = suppressor of G2 allele of SKP1)

  2. Fusion of human SGT1 (hSGT1 (show ECD Proteins)) to NOD1 (show NOD1 Proteins) LRR significantly enhanced the solubility, and the fusion protein was stabilized by coexpression of mouse Hsp90alpha (show HSP90AA2 Proteins).

  3. Data (including data from studies using purified proteins/hepatocyte lysates) suggest eEF1A1 (show EEF1A1 Proteins)/Sgt1a interact as multimer; D2/D3 domains of eEF1A1 (show EEF1A1 Proteins) and TPR domain of Sgt1 are involved in multimer formation; Sgt1 competes with viral RNA to bind to eEF1A (show EEF1A1 Proteins).

  4. Data suggest that SspH2 (ubiquitin ligase effector from Salmonella typhimurium) ubiquitination activity and protein stability is enhanced by SGT1.

  5. our data revealed a previously uncovered role of SGT1 in gastric cancer development, and suggested that SGT1 could be a promising anti-cancer target to against gastric cancer

  6. Chp-1 (show CHP Proteins) and melusin (show ITGB1BP2 Proteins) can interact with cochaperones PP5 (show PPP5C Proteins) and Sgt1 and with each other in an ATP-dependent manner

  7. Plk1 is required for the kinetochore localization of Sgt1 and phosphorylates serine 331 of Sgt1 at the kinetochores.

  8. Sgt1 translocates to the nucleus due to heat shock. S100A6 (show S100A6 Proteins) is necessary for nuclear translocation of the Sgt1 protein.

  9. S100A6 (show S100A6 Proteins)-Ca(2 (show CA2 Proteins)+)-mediated Sgt1 dephosphorylation promotes its nuclear translocation, most likely due to disruption of the Sgt1-Hsp90 (show HSP90 Proteins) complex

  10. SUGT1 amplification might give rise to promoting transcription of the gene directly subsequent to the progression of colorectal cancer cases with worsening prognosis

Mouse (Murine) SGT1, Suppressor of G2 Allele of SKP1 (S. Cerevisiae) (SUGT1) interaction partners

  1. Chp-1 (show CHORDC1 Proteins) and melusin (show ITGB1BP2 Proteins) can interact with cochaperones PP5 (show PPP5C Proteins) and Sgt1 and with each other in an ATP-dependent manner

SGT1, Suppressor of G2 Allele of SKP1 (S. Cerevisiae) (SUGT1) Protein Profile

Protein Summary

This gene is homologous to the yeast gene SGT1, which encodes a protein involved in kinetochore function and required for the G1/S and G2/M transitions. Complementation studies suggest that the human protein has similar functions. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with SUGT1

  • suppressor of G2 allele of SKP1 homolog (LOC100402050)
  • SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae) (SUGT1)
  • suppressor of G2 allele of SKP1 homolog (LOC100481572)
  • suppressor of G2 allele of SKP1 homolog (LOC100512856)
  • suppressor of G2 allele of SKP1 homolog (LOC100543240)
  • suppressor of G2 allele of SKP1 homolog (LOC100595307)
  • suppressor of G2 allele of SKP1 homolog (LOC100598627)
  • suppressor of G2 allele of SKP1 homolog (LOC100631434)
  • suppressor of G2 allele of SKP1 homolog (LOC100645570)
  • LOC100282745 (IDP1602)
  • SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae) (Sugt1)
  • 2410174K12Rik protein
  • Aa1114 protein
  • SGT1 protein

Protein level used designations for SUGT1

suppressor of G2 allele of SKP1 homolog , PCO098564 , PCO098564(275) , PCO098564_ov , suppressor of G2 allele of SKP1 , SGT1B protein , putative 40-6-3 protein , suppressor of G2 allele of SKP1, S. cerevisiae, homolog of

GENE ID SPECIES
100402050 Callithrix jacchus
100455328 Pongo abelii
100481572 Ailuropoda melanoleuca
100512856 Sus scrofa
100543240 Meleagris gallopavo
100595307 Nomascus leucogenys
100598627 Nomascus leucogenys
100631434 Amphimedon queenslandica
100645570 Bombus terrestris
418827 Gallus gallus
100282745 Zea mays
10910 Homo sapiens
67955 Mus musculus
290408 Rattus norvegicus
515509 Bos taurus
609605 Canis lupus familiaris
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