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SH3RF1 encodes a protein containing an N-terminus RING-finger, four SH3 domains, and a region implicated in binding of the Rho GTPase Rac. Additionally we are shipping SH3RF1 Proteins (4) and many more products for this protein.
Showing 10 out of 30 products:
Human Monoclonal SH3RF1 Primary Antibody for WB - ABIN393739
Rose, Behm, Drgon, Johnson, Uhl: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. in Molecular medicine (Cambridge, Mass.) 2010
Show all 5 references for ABIN393739
Cow (Bovine) Polyclonal SH3RF1 Primary Antibody for WB - ABIN2774771
Lyons, Thorburn, Ryan, Thorburn, Anderson, Kassenbrock: Regulation of the Pro-apoptotic scaffolding protein POSH by Akt. in The Journal of biological chemistry 2007
Human Polyclonal SH3RF1 Primary Antibody for ELISA, WB - ABIN566141
Wilhelm, Xu, Kukekov, Gire, Greene: Proapoptotic Nix activates the JNK pathway by interacting with POSH and mediates death in a Parkinson disease model. in The Journal of biological chemistry 2007
Human Monoclonal SH3RF1 Primary Antibody for ELISA, WB - ABIN566142
Wilhelm, Kukekov, Schmit, Biagas, Sproul, Gire, Maes, Xu, Greene: Sh3rf2/POSHER protein promotes cell survival by ring-mediated proteasomal degradation of the c-Jun N-terminal kinase scaffold POSH (Plenty of SH3s) protein. in The Journal of biological chemistry 2012
the active JNK (show MAPK8 Antibodies) signaling complex formed of POSH and the JNK (show MAPK8 Antibodies) module is essential for the expression of anterior neural genes and apoptosis in anterior development
We found a genome-wide significant association for rs2282987 in CDK6 (show CDK6 Antibodies) and a consistent association for rs2706748 in SH3RF1 .
The data presented here define POSH and Siah2 (show SIAH2 Antibodies) as important mediators of death receptor mediated apoptosis and suggest targeting the interaction of these two E3 ligases is a promising novel cancer therapeutic strategy.
POSH promotes cell survival in Drosophila and in human rheumatoid arthritis synovial fibroblasts
POSH disassociates from the JNK (show MAPK8 Antibodies) complex after phosphorylation of MLK3 (show MAP3K11 Antibodies) by Akt2 (show AKT2 Antibodies), which leads to down-regulation of the JNK (show MAPK8 Antibodies) signaling pathway
Results identified ALIX (show PDCD6IP Antibodies) as an ubiquitination substrate of POSH and indicate that POSH and ALIX (show PDCD6IP Antibodies) cooperate to facilitate efficient virus release.
POSH inhibits ROMK (show KCNJ1 Antibodies) channels by enhancing dynamin (show DNM1 Antibodies)-dependent and clathrin-independent endocytosis and by stimulating ubiquitination of ROMK (show KCNJ1 Antibodies) channels.
identify plenty of SH3 (POSH) and JNK-interacting protein 1 (JIP-1 (show MAPK8IP1 Antibodies)) as a multiprotein scaffold network for TCR-mediated JNK1 (show MAPK8 Antibodies) activation in CD8 (show CD8A Antibodies)(+) T cells.
a mechanism by which POSH regulates the localization of activated Rac1 and F-actin assembly to control PCDLP formation and subsequent somal translocation of migratory neurons.
An intracellular signaling pathway for process outgrowth inhibition by Nogo66 implicates the POSH complex as a therapeutic target to enhance axon outgrowth and plasticity in the injured central nervous system.
Siah1 (show SIAH1 Antibodies) is a binding partner for POSH (plenty of SH3s), a scaffold component of the apoptotic JNK (show MAPK8 Antibodies) pathway
POSH and JIPs directly associate with one another to form a multiprotein complex, PJAC (POSH-JIP (show SMAD4 Antibodies) apoptotic complex), that includes all of the known kinase components of the pathway.
Results suggest that the molecular scaffold protein POSH assembles an inhibitory complex that links to the actin-myosin network to regulate neuronal process outgrowth.
This gene encodes a protein containing an N-terminus RING-finger, four SH3 domains, and a region implicated in binding of the Rho GTPase Rac. Via the RING-finger, the encoded protein has been shown to function as an ubiquitin-protein ligase involved in protein sorting at the trans-Golgi network. The encoded protein may also act as a scaffold for the c-Jun N-terminal kinase signaling pathway, facilitating the formation of a functional signaling module.
SH3 multiple domains 2
, SH3 domain containing ring finger 1
, putative E3 ubiquitin-protein ligase SH3RF1
, plenty of SH3s
, SH3 domain-containing RING finger protein 1
, E3 ubiquitin-protein ligase SH3RF1
, SH3 multiple domains protein 2
, plenty of SH3 domains
, ring finger protein 142
, putative scaffolding protein POSH