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The zeta-sarcoglycan gene measures over 465 kb and localizes to 8p22. Additionally we are shipping SGCZ Antibodies (4) and many more products for this protein.
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Zeta-sarcoglycan is an integral component of the sarcoglycan (show SGCD Proteins) complex and is important in the pathogenesis of muscular dystrophy.
No pathogenic SGCZ mutations were identified
three CNVs associated with BMI, obesity, and other obesity-related traits after adjusting for multiple testing. These CNVs overlap the PARK2 (show PARK2 Proteins), GYPA (show GYPA Proteins), and SGCZ genes
The zeta-sarcoglycan gene measures over 465 kb and localizes to 8p22. This protein is part of the sarcoglycan complex, a group of 6 proteins. The sarcoglycans are all N-glycosylated transmembrane proteins with a short intra-cellular domain, a single transmembrane region and a large extra-cellular domain containing a carboxyl-terminal cluster with several conserved cysteine residues. The sarcoglycan complex is part of the dystrophin-associated glycoprotein complex (DGC), which bridges the inner cytoskeleton and the extra-cellular matrix.
, sarcoglycan zeta