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Cell surface receptor for PLXNB2 that plays an important role in cell-cell signaling. Additionally we are shipping SEMA4C Antibodies (54) and SEMA4C Kits (8) and many more products for this protein.
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Data show that G-protein-coupled receptor (show ADRA1A Proteins) kinase-interacting protein (show CIB1 Proteins) 1 (GIT1) and semaphorin 4C (SEMA4C) were found to have putative microRNA miR (show MLXIP Proteins)-138 binding sites in their 3' untranslated region (3'UTRs).
Suggest that up-regulation of miR (show MLXIP Proteins)-125b or targeting Sema4C could serve as novel approaches to reverse chemotherapy resistance in breast cancers.
Data suggest that Erbin (show ERBB2IP Proteins) can interact with Sema4C, and co-expression of Erbin (show ERBB2IP Proteins) blocks the process of Sema4C-induced epithelial-mesenchymal transition.
There is a high expression of Sema4C in esophageal cancer, gastric cancer and rectal cancer, and expression is strongly correlated with lymphatic metastasis.
High Sema4C is associated with epithelial-mesenchymal transition and renal fibrosis.
Sema4C-Plexin B2 (show PLXNB2 Proteins) signalling regulates ureteric branching
We have identified here Sema4C and Sema4G (show SEMA4G Proteins) as candidate ligands for Plexin-B2 (show PLXNB2 Proteins)
Plexin-B2 (show PLXNB2 Proteins) and Sema4C are potential regulators of the vascular and endocrine system.
Results suggest a putative role of Sema4C during neurogenesis both in vivo and in vitro.
Sema4C-mediated interaction among myoblasts plays an important role in terminal myogenic differentiation
Sema4C promotes terminal myogenic differentiation in a p38 MAPK (show MAPK14 Proteins)-dependent manner.
Cell surface receptor for PLXNB2 that plays an important role in cell-cell signaling. PLXNB2 binding promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. Required for normal brain development, axon guidance and cell migration. Probable signaling receptor which may play a role in myogenic differentiation through activation of the stress- activated MAPK cascade.
, sema I
, semaphorin I
, semaphorin-C-like 1