Sema Domain, Transmembrane Domain (TM), and Cytoplasmic Domain, (Semaphorin) 6A Proteins (SEMA6A)

The transmembrane semaphorin SEMA6A is expressed in developing neural tissue and is required for proper development of the thalamocortical projection (Leighton et al., 2001 [PubMed 11242070]).[supplied by OMIM, Feb 2011].. Additionally we are shipping SEMA6A Antibodies (92) and SEMA6A Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SEMA6A 57556 Q9H2E6
SEMA6A 20358 O35464
Rat SEMA6A SEMA6A 361324  
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Top SEMA6A Proteins at antibodies-online.com

Showing 4 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
HOST_Human Cells Human His tag 50 μg Log in to see 20 to 21 Days
$382.80
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HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details

SEMA6A Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)
,

More Proteins for Sema Domain, Transmembrane Domain (TM), and Cytoplasmic Domain, (Semaphorin) 6A (SEMA6A) Interaction Partners

Zebrafish Sema Domain, Transmembrane Domain (TM), and Cytoplasmic Domain, (Semaphorin) 6A (SEMA6A) interaction partners

  1. Sema6a and Plxna2 (show Plxna2 Proteins) have roles in promoting eye vesicle cohesion through mediating spatially regulated repulsion within the developing zebrafish eye

Human Sema Domain, Transmembrane Domain (TM), and Cytoplasmic Domain, (Semaphorin) 6A (SEMA6A) interaction partners

  1. miR (show MLXIP Proteins)-203 induces the apoptosis of YD-38 human oral cancer cells by directly targeting SEMA6A.

  2. our findings indicated that SEMA6A may be a potential prognostic biomarker in the treatment of Glioblastoma multiforme

  3. Data suggest that Sema6A and Mical1 (show MICAL1 Proteins) may represent new potential therapeutic targets in BRAFV600E melanoma.

  4. We identified the SEMA6A and HLA-DP (show HLA-DPB1 Proteins) loci as significant contributors to risk for granulomatosis with polyangiitis.

  5. Data show that miR (show MLXIP Proteins)-27a/b regulated the expression of the angiogenesis inhibitor semaphorin 6A (SEMA6A) in vitro and in vivo and targeted the 3'-untranslated region of SEMA6A.

  6. Strong expression of SEMA6A is associated with langerhans cells of histiocytosis or dermatopathic lymphadenitis

  7. NANOG (show NANOG Proteins)-, SOX2 (show SOX2 Proteins)-, and POU5F1 (OCT3/OCT4 (show POU5F1 Proteins))-binding sites within intron 1 of the SEMA6A gene

  8. findings suggest for SEMA6A a novel function in the cytoskeleton and a role in modulating tubulin (show TUBB Proteins) isotype composition and microtubule dynamics

Mouse (Murine) Sema Domain, Transmembrane Domain (TM), and Cytoplasmic Domain, (Semaphorin) 6A (SEMA6A) interaction partners

  1. The experiments reveal the complex nature of Sema6A biochemical functions and the molecular logic of the context-dependent interactions between Sema6A and PlxnA2 (show Plxna2 Proteins).

  2. Using time-lapse videomicroscopy we provide evidence that Sema6A/PlexinA2 signaling participates to interkinetic nuclear migration of retinal progenitor cell

  3. findings reveal a unique function of Nrf2 (show NFE2L2 Proteins) in reprogramming ischemic tissue toward neurovascular repair via Sema6A regulation, providing a potential therapeutic strategy for ischemic retinal and CNS diseases

  4. Tangential migration is selectively altered in cerebellar neurons of Sema6A knockouts.

  5. semaphorin 6A is expressed in On starburst amacrine cell.

  6. Sema6A expressed in oligodendrocyte precursor cells is involved in their autonomous migration through ligand-receptor interaction with Plexin-A4 (show PLXNA4 Proteins) expressed in surrounding cells.

  7. The results of this study suggested that Sema6A might have a role in myelination by controlling oligodendrocyte differentiation.

  8. Adult Sema6A-null mice exhibit reduced tumor, matrigel, and choroidal angiogenesis compared with controls. Here we show that it also regulates vascular development and adult angiogenesis.

  9. null mutations in Sema6A or PlexinA4 (PlexA4 (show PLXNA4 Proteins)) exhibit a pronounced defect in OPL (show ZIC1 Proteins) stratification of horizontal cell axons without any apparent deficits in bipolar cell dendrite or photoreceptor axon targeting.

  10. Mice with mutations in Sema6A or the interacting genes may thus represent a highly informative model for how neurodevelopmental defects can lead to anatomical dysconnectivity.

SEMA6A Protein Profile

Protein Summary

The transmembrane semaphorin SEMA6A is expressed in developing neural tissue and is required for proper development of the thalamocortical projection (Leighton et al., 2001

Gene names and symbols associated with SEMA6A

  • sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A (sema6a)
  • sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A (SEMA6A)
  • sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A (Sema6a)
  • 9330158E07 protein
  • A730020P05Rik protein
  • AI851735 protein
  • b2b997Clo protein
  • fj46c12 protein
  • HT018 protein
  • SEMA protein
  • SEMA6A protein
  • Sema6A-1 protein
  • SEMA6A1 protein
  • Semaq protein
  • VIa protein
  • wu:fj46c12 protein
  • zgc:66106 protein

Protein level used designations for SEMA6A

semaphorin 6a , semaphorin-6A , semaphorin 6A1 , sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A , semaphorin-6A-like , SEMA6A-1 , sema VIa , semaphorin 6A-1 , semaphorin VIA , semaphorin-6A-1 , Mutant line 997 , sema Q , sema VIA , semaphorin Q

GENE ID SPECIES
336060 Danio rerio
427387 Gallus gallus
462014 Pan troglodytes
100014958 Monodelphis domestica
100082422 Ornithorhynchus anatinus
100355525 Oryctolagus cuniculus
100395044 Callithrix jacchus
100443615 Pongo abelii
100472243 Ailuropoda melanoleuca
100493034 Xenopus (Silurana) tropicalis
100563546 Anolis carolinensis
100597845 Nomascus leucogenys
57556 Homo sapiens
20358 Mus musculus
481432 Canis lupus familiaris
100522008 Sus scrofa
516019 Bos taurus
361324 Rattus norvegicus
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