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SEPT11 belongs to the conserved septin family of filament-forming cytoskeletal GTPases that are involved in a variety of cellular functions including cytokinesis and vesicle trafficking (Hanai et al., 2004 [PubMed 15196925]\; Nagata et al., 2004 [PubMed 15485874]).[supplied by OMIM, Jul 2009].. Additionally we are shipping Septin 11 Antibodies (48) and many more products for this protein.
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Authors report here that the septins SEPT2 (show SEPT2 Proteins), -9, -11, and probably -7 form fibrillar structures around the chlamydial inclusion.
The proteomic discovery of insoluble SEPT11 accumulation in FTLD-U, along with novel pathological associations, highlights a role for this cytoskeleton-associated protein in the pathogenesis of this complex disorder.
the role of SEPT2 (show SEPT2 Proteins) and SEPT11 in the InlB-Met interactions
Cloned and characterised novel SEPT11 variants and investigated interaction partners of SEPT11 in platelets and human umbilical vein endothelial cells.
LOH in genes around D4S2964, including ARD1B (show NAA11 Proteins) and SEPT11 may play an important role in hepatocellular carcinoma development and progression
Sept7 (show SEPT7 Proteins)/9b/11 form a complex that has effects on filament elongation, bundling, or disruption
SEPT9 (show SEPT9 Proteins) sequence alternations causing hereditary neuralgic amyotrophy are associated with altered interactions with SEPT4 (show SEPT4 Proteins)/SEPT11 and resistance to Rho/Rhotekin (show RTKN Proteins)-signaling
Our finding suggests a role for members of the septin (show SEPT6 Proteins) family in the development of proliferative retinal membranes.
SEPT2 (show SEPT2 Proteins) is essential for the InlB-mediated entry of Listeria, but SEPT11 is not, which distinguishes the roles of different mammalian septins
SEPT11 is involved in vesicle trafficking and may play a role in synaptic connectivity. Interestingly, mice that harbor a homozygous Sept11 null mutation, die in utero.
SEPT11 belongs to the conserved septin family of filament-forming cytoskeletal GTPases that are involved in a variety of cellular functions including cytokinesis and vesicle trafficking (Hanai et al., 2004
, septin 6