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SDPR encodes a calcium-independent phospholipid-binding protein whose expression increases in serum-starved cells. Additionally we are shipping SDPR Kits (17) and SDPR Proteins (4) and many more products for this protein.
Showing 10 out of 34 products:
Hamster Polyclonal SDPR Primary Antibody for FACS, IHC (p) - ABIN653890
Baig, Bao, Haslam: Proteomic identification of pleckstrin-associated proteins in platelets: possible interactions with actin. in Proteomics 2009
Show all 2 references for ABIN653890
Human Polyclonal SDPR Primary Antibody for ELISA, ICC - ABIN4352368
Hill, Bastiani, Luetterforst, Kirkham, Kirkham, Nixon, Walser, Abankwa, Oorschot, Martin, Hancock, Parton: PTRF-Cavin, a conserved cytoplasmic protein required for caveola formation and function. in Cell 2008
Show all 2 references for ABIN4352368
Hamster Polyclonal SDPR Primary Antibody for FACS, IHC (p) - ABIN954696
Hansen, Bright, Howard, Nichols: SDPR induces membrane curvature and functions in the formation of caveolae. in Nature cell biology 2009
Show all 2 references for ABIN954696
Hepatocellular carcinoma patients with lower cavin-2 expression have a relatively poor prognosis.
identification of a novel metastasis suppressor gene, serum deprivation response (SDPR), localized to 2q32-33, a region reported to be associated with significant loss of heterozygosity in breast cancer, is reported.
Cavin-1 (show PTRF Antibodies) and cavin-2 are strongly expressed within caveolae-like structures within liver sinusoidal endothelial cells of the hepatitis C-related cirrhotic liver and cavin-1 (show PTRF Antibodies) would play a critical role in regulating aspects of caveolin-1 (show CAV1 Antibodies).
Rather than forming a single coat complex containing the three cavin (show PTRF Antibodies) family members, single-molecule analysis reveals an exquisite specificity of interactions between cavin1 (show PTRF Antibodies), cavin2 and cavin3 (show PRKCDBP Antibodies).
Three genes (LY96 (show LY96 Antibodies), IL8 (show IL8 Antibodies) DPR (show DACT1 Antibodies)) were significantly downregulated over time. This finding was confirmed in a validation cohort of stroke patients (n=8).
The cavin (show PTRF Antibodies) family protein Polymerase 1 and transcript release factor, SRBC (show CD2 Antibodies) and serum deprivation response protein were down regulated in breast cancer cell lines and breast tumor tissue.
Study conclude that SDPR is a membrane-curvature-inducing component of caveolae, and that STB-induced membrane tubulation is facilitated by caveolae.
This gene encodes a calcium-independent phospholipid-binding protein whose expression increases in serum-starved cells. This protein is a substrate for protein kinase C (PKC) phosphorylation and recruits polymerase I and transcript release factor (PTRF) to caveolae. Removal of this protein causes caveolae loss and its over-expression results in caveolae deformation and membrane tubulation.
serum deprivation response
, serum deprivation response (phosphatidylserine binding protein)
, serum deprivation response protein
, serum deprivation-response protein-like
, phosphatidylserine binding protein
, phosphatidylserine-binding protein
, serum deprivation-response protein