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anti-Sialidase 1 (Lysosomal Sialidase) (NEU1) Antibodies

The protein encoded by NEU1 is a lysosomal enzyme that cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. Additionally we are shipping NEU1 Proteins (11) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NEU1 18010 O35657
NEU1 24591  
NEU1 4758 Q99519
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Top anti-NEU1 Antibodies at antibodies-online.com

Showing 10 out of 52 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated WB NEU1 Antibody (Center) (ABIN1881576) western blot analysis in HepG2 cell line lysates (35 µg/lane). This demonstrates the NEU1 antibody detected the NEU1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated ELISA, WB NEU1 polyclonal antibody (A01), Lot # 060703JCS1. Western Blot analysis of NEU1 expression in human ovarian cancer. Western Blot detection against Immunogen (35.13 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of NEU1 Antibody (Center) (ABIN653650) in MDA-MB231 cell line lysates (35 µg/lane). NEU1 (arrow) was detected using the purified polyclonal antibody. NEU1 Antibody (Center) (ABIN653650)IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated IHC (p), WB 100 μL Log in to see 8 to 10 Days
$493.17
Details
Human Mouse Un-conjugated WB 100 μL Log in to see 8 to 10 Days
$493.17
Details
Human Mouse Un-conjugated WB 100 μL Log in to see 8 to 10 Days
$529.83
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 100 μg Log in to see 2 to 3 Days
$343.75
Details
Human Mouse Un-conjugated IP, WB   100 μg Log in to see 8 to 10 Days
$793.83
Details
Human Rabbit Un-conjugated IHC, WB NEU1 antibody was used for immunohistochemistry at a concentration of 4-8 ug/ml to stain Skeletal muscle cells (arrows) in Human Muscle. Magnification is at 400X NEU1 antibody was used for immunohistochemistry at a concentration of 4-8 ug/ml. Magnification is at 400X 100 μg Log in to see 3 to 4 Days
$388.93
Details

NEU1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine)


Rat (Rattus)


Human ,
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Top referenced anti-NEU1 Antibodies

  1. Human Polyclonal NEU1 Primary Antibody for WB - ABIN1881576 : Caciotti, Di Rocco, Filocamo, Grossi, Traverso, dAzzo, Cavicchi, Messeri, Guerrini, Zammarchi, Donati, Morrone: Type II sialidosis: review of the clinical spectrum and identification of a new splicing defect with chitotriosidase assessment in two patients. in Journal of neurology 2009 (PubMed)
    Show all 3 references for ABIN1881576

  2. Cow (Bovine) Polyclonal NEU1 Primary Antibody for IHC, WB - ABIN2781801 : Hinek, Pshezhetsky, von Itzstein, Starcher: Lysosomal sialidase (neuraminidase-1) is targeted to the cell surface in a multiprotein complex that facilitates elastic fiber assembly. in The Journal of biological chemistry 2006 (PubMed)

  3. Human Polyclonal NEU1 Primary Antibody for ELISA, WB - ABIN561961 : Bilyy, Shkandina, Tomin, Muñoz, Franz, Antonyuk, Kit, Zirngibl, Fürnrohr, Janko, Lauber, Schiller, Schett, Stoika, Herrmann: Macrophages discriminate glycosylation patterns of apoptotic cell-derived microparticles. in The Journal of biological chemistry 2012 (PubMed)

More Antibodies against NEU1 Interaction Partners

Mouse (Murine) Sialidase 1 (Lysosomal Sialidase) (NEU1) interaction partners

  1. Neu1 (show NEURL Antibodies) desialylation is a mechanism of Fc-independent platelet clearance in immune thrombocytopenia.

  2. Data indicate a role for neuraminidase 1 (Neu1) in regulating Siglec E protein-toll-like receptor 4 (TLR4 (show TLR4 Antibodies)) interaction and endotoxemia.

  3. elastin (show ELN Antibodies)-derived peptides as an enhancer of atherogenesis and defines the Neuraminidase 1/PI3Kgamma (show PIK3CG Antibodies) signalling pathway as a key mediator

  4. significant increases in Col1a1 (show COL1A1 Antibodies), serine/threonine-protein kinase 1, Ctnnb1 (show CTNNB1 Antibodies), CSRNP1 (show CSRNP1 Antibodies), Ddit4 (show DDIT4 Antibodies), Cyp2e1 (show CYP2E1 Antibodies), and Krit1 (show KRIT1 Antibodies) expressions and great decreases inreceptor D2, Neu1 (show NEURL Antibodies), and Dhcr7 (show DHCR7 Antibodies) expressions following long-term exposure to TiO2 NPs (show NPS Antibodies)

  5. NEU1 (show NEURL Antibodies) deficiency has a role in determining amyloid precursor protein (show APP Antibodies) levels and amyloid-beta secretion via deregulated lysosomal exocytosis

  6. Neu1 (show NEURL Antibodies) sialidase and matrix metalloproteinase-9 (show MMP9 Antibodies) cross-talk regulates nucleic acid-induced endosomal TOLL-like receptor-7 (show TLR7 Antibodies) and -9 activation, cellular signaling and pro-inflammatory responses.

  7. The activity of NEU1 (show NEURL Antibodies) was preferentially higher in epididymal fat and lower in the livers of two strains of obese and diabetic mice.

  8. these studies identify Neu1 (show NEURL Antibodies) as a novel component of the signaling pathways of energy metabolism and glucose uptake.

  9. The rescue of sialidase activity in hypomorphic sialidase mice using helper-dependent adenovirus resulted in increased VLDL production and an increase in MTP (show LAPTM4A Antibodies) levels.

  10. Data indicate that sialidases Neu1 (show NEURL Antibodies) and Neu3 (show Neu3 Antibodies) are present on sperm, and their activity is required for capacitation and zona pellucida binding.

Human Sialidase 1 (Lysosomal Sialidase) (NEU1) interaction partners

  1. How the point mutations of the neuraminidase (show NEU Antibodies) sequences affected the susceptibility of H9N2 virus to oseltamivir is still to be determined and deserve further investigations

  2. Basal Neu-1 catalytic activity is strongly increased in aged cells.

  3. Neu1 desialylation is a mechanism of Fc-independent platelet clearance in immune thrombocytopenia.

  4. Flagellin (show FliC Antibodies) drives NEU1 to desialylate MUC1 (show MUC1 Antibodies), thereby increasing its adhesiveness for Pseudomonas aeruginosa and its shedding

  5. Muc1 (show MUC1 Antibodies) clearly plays a significant role in enhancing the hypoxia-inducible transcription factors protective pathway during ischemic insult and recovery in kidney epithelia

  6. This study analyzed patient cells with GM1 gangliosidosis and sialidosis. A novel mutation p.R347Q is identified in NEU1 gene.

  7. The lymphocyte levels of NEU1 and ST6GAL1 (show ST6GAL1 Antibodies) mRNA expression are significantly increased in erythremia.

  8. Insulin (show INS Antibodies)-induced phosphorylation of the insulin receptor (show INSR Antibodies) is dependent on Neu1 sialidase activity.

  9. Sialidosis should be suspected and the NEU1 gene analyzed in patients with isolated action myoclonus presenting in adulthood in the absence of other typical clinical and laboratory findings.

  10. catalytically active NEU1 inhibits in vitro angiogenesis through desialylation of its substrate, CD31 (show HBA1 Antibodies)

Cow (Bovine) Sialidase 1 (Lysosomal Sialidase) (NEU1) interaction partners

  1. NEU1 gene is not responsible for the lysosomal storage disease of Japanese Black cattle.

NEU1 Antigen Profile

Protein Summary

The protein encoded by this gene is a lysosomal enzyme that cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A (the latter is also referred to as 'protective protein'). Mutations in this gene can lead to sialidosis, a lysosomal storage disease that can be type 1 (cherry red spot-myoclonus syndrome or normosomatic type), which is late-onset, or type 2 (the dysmorphic type), which occurs at an earlier age with increased severity.

Gene names and symbols associated with NEU1

  • sialidase 1 (lysosomal sialidase) (neu1) antibody
  • sialidase 1 (lysosomal sialidase) (NEU1) antibody
  • neuraminidase 1 (neu1) antibody
  • neuraminidase 1 (Neu1) antibody
  • AA407268 antibody
  • AA407316 antibody
  • Aglp antibody
  • Apl antibody
  • Bat-7 antibody
  • Bat7 antibody
  • G9 antibody
  • Map-2 antibody
  • MGC81958 antibody
  • NANH antibody
  • NEU antibody
  • Neu-1 antibody
  • SIAL1 antibody

Protein level used designations for NEU1

sialidase 1 (lysosomal sialidase) , neuraminidase , sialidase-1 , isotocin , Isotocin-neurophysin IT 1 , neuraminidase 1 , sialidase-1-like , G9 sialidase , HLA-B-associated transcript 7 , N-acetyl-alpha-neuraminidase 1 , lysosomal sialidase , sialidase 1 , acetylneuraminyl hydrolase , exo-alpha-sialidase

GENE ID SPECIES
444511 Xenopus laevis
471968 Pan troglodytes
716740 Macaca mulatta
100136555 Salmo salar
100342130 Oryctolagus cuniculus
100408501 Callithrix jacchus
100595428 Nomascus leucogenys
18010 Mus musculus
24591 Rattus norvegicus
4758 Homo sapiens
481717 Canis lupus familiaris
100124381 Sus scrofa
505554 Bos taurus
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