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anti-Sialidase 2 (Cytosolic Sialidase) (NEU2) Antibodies

NEU2 belongs to a family of glycohydrolytic enzymes which remove sialic acid residues from glycoproteins and glycolipids. Additionally we are shipping NEU2 Proteins (7) and NEU2 Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NEU2 23956 Q9JMH3
NEU2 29204  
NEU2 4759 Q9Y3R4
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Top anti-NEU2 Antibodies at antibodies-online.com

Showing 10 out of 55 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, IF, IHC (p), WB Confocal immunofluorescent analysis of NEU2 Antibody (N-term)(ABIN656123) with A549 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red). DAPI was used to stain the cell nuclear (blue). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, FACS, IF, IHC (p), WB Flow cytometric analysis of A549 cells using NEU2 Antibody (N-term) Cat.-No AP52855PU-N (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Confocal immunofluorescent analysis of NEU2 Antibody (N-term) Cat.-No AP52855PU-N with A549 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red). DAPI was used to stain the cell nuclear (blue). 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated EIA, IHC (fro), IF, IP, WB Western blot analysis using Rockland Immunochemical's Affinity Purified anti-Neu2 antibody to detect recombinant His tagged Neu-2 (1.0 ug loaded). Molecular weight marker (not shown) indicates a single band of the expected MW (43 kDa). The blot was incubated with a 1:500 dilution of the antibody at room temperature for 1 h followed by detection using IRDye™800 labeled Goat-a-Rabbit IgG [H&L] diluted 1:1,000. IRDye™800 fluorescence image was captured using the Odyssey® Infrared Imaging System developed by LI-COR. IRDye is a trademark of LI-COR, Inc. Other detection systems will yield similar results. Western blot analysis using Affinity Purified anti-Neu2 antibody to detect Neu-2 present in a lysate expressing human Neu2 (1.0 ul loaded). Molecular weight marker (not shown) indicates a band of the expected MW (43 kDa). The reactive lower molecular weight band is believed to represent a truncated form of this protein. The blot was incubated with a 1:500 dilution of the antibody at room temperature for 1 h followed by detection using IRDye™800 labeled Goat-a-Rabbit IgG [H&L] diluted 1:1,000. IRDye™800 fluorescence image was captured using the Odyssey® Infrared Imaging System developed by LI-COR. IRDye is a trademark of LI-COR, Inc. Other detection systems will yield similar results. 0.1 mg Log in to see 6 to 8 Days
$500.50
Details
Human Mouse Un-conjugated WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY NEU2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-NEU2. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated IF, WB Anti-NEU2 mouse monoclonal antibody (ABIN2454580) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY NEU2 (RC219858). HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY NEU2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-NEU2. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated ELISA, WB NEU2 monoclonal antibody (M03), clone 3B9. Western Blot analysis of NEU2 expression in human liver. NEU2 monoclonal antibody (M03), clone 3B9. Western Blot analysis of NEU2 expression in human fetal liver. 100 μg Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated FACS, IF, WB Anti-NEU2 mouse monoclonal antibody (ABIN2454605) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY NEU2 (RC219858). HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY NEU2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-NEU2. 100 μL Log in to see 2 to 3 Days
$482.90
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged NEU2 is approximately 3 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Mouse Un-conjugated ELISA Detection limit for recombinant GST tagged NEU2 is approximately 1 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 8 to 10 Days
$610.50
Details

NEU2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine)


Rat (Rattus)


Human ,
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Top referenced anti-NEU2 Antibodies

  1. Human Polyclonal NEU2 Primary Antibody for EIA, FACS - ABIN954803 : Stoppani, Rossi, Marchesini, Preti, Fanzani: Defective myogenic differentiation of human rhabdomyosarcoma cells is characterized by sialidase Neu2 loss of expression. in Cell biology international 2009 (PubMed)
    Show all 4 references for ABIN954803

  2. Human Polyclonal NEU2 Primary Antibody for EIA, IHC (fro) - ABIN117994 : Fanzani, Giuliani, Colombo, Zizioli, Presta, Preti, Marchesini: Overexpression of cytosolic sialidase Neu2 induces myoblast differentiation in C2C12 cells. in FEBS letters 2003 (PubMed)
    Show all 4 references for ABIN117994

  3. Human Monoclonal NEU2 Primary Antibody for ELISA, WB - ABIN518292 : Bilyy, Shkandina, Tomin, Muñoz, Franz, Antonyuk, Kit, Zirngibl, Fürnrohr, Janko, Lauber, Schiller, Schett, Stoika, Herrmann: Macrophages discriminate glycosylation patterns of apoptotic cell-derived microparticles. in The Journal of biological chemistry 2012 (PubMed)
    Show all 2 references for ABIN518292

  4. Human Polyclonal NEU2 Primary Antibody for FACS, IF - ABIN656123 : Seyrantepe, Landry, Trudel, Hassan, Morales, Pshezhetsky: Neu4, a novel human lysosomal lumen sialidase, confers normal phenotype to sialidosis and galactosialidosis cells. in The Journal of biological chemistry 2004 (PubMed)
    Show all 2 references for ABIN656123

More Antibodies against NEU2 Interaction Partners

Mouse (Murine) Sialidase 2 (Cytosolic Sialidase) (NEU2) interaction partners

  1. Neu2 from thymus exhibited sialidase activity with fetuin (show AHSG Antibodies) at pH 7.0.

  2. Our data demonstrate that IGF-1 (show IGF1 Antibodies)-induced myoblast differentiation and hypertrophy are driven, at least in part, by Neu2 upregulation and further support the significant role of cytosolic sialidase in myoblasts.

  3. the lack of soluble sialidase activity in the SM/J mouse thymus is due to the thymus-specific low expression level of the Neu2 gene

  4. 30-40% of B and C forms of Neu2 activity was located in the crude membrane-fraction, and hydrolyzed ganglioside effectively, while both soluble fraction showed particular behavior with substrate specificity.

Human Sialidase 2 (Cytosolic Sialidase) (NEU2) interaction partners

  1. cytosolic GBA3 (show GBA3 Antibodies) is likely involved in the catabolism of cytosolic sialyl free N-glycans, possibly by stabilizing the activity of the NEU2 protein

  2. Circular dichroism (CD) spectra at variable temperatures have been recorded for human cytosolic sialidase NEU2 in buffered water solutions and in the presence of divalent cations.

  3. Q136K is a novel mutation in an expressed NEU2 protein that was discovered during crystallographic analysis.

  4. the present study demonstrated NEU2 expression to be detectable but very low in many human tissues and cells, and suggested possible functional roles in PC-3 (show PCSK1 Antibodies) prostate cancer cells.

  5. NEU2 appears to be activated when lysine 45 and glutamine (show GFPT1 Antibodies) 112 are mutated to alanine.

  6. the first high resolution x-ray structures of sialidase, human Neu2

  7. Neu2 loss of expression might exacerbate the defective myogenic differentiation of rhabdomyosarcoma cells.

NEU2 Antigen Profile

Protein Summary

This gene belongs to a family of glycohydrolytic enzymes which remove sialic acid residues from glycoproteins and glycolipids. Expression studies in COS7 cells confirmed that this gene encodes a functional sialidase. Its cytosolic localization was demonstrated by cell fractionation experiments.

Gene names and symbols associated with NEU2

  • sialidase 2 (cytosolic sialidase) (NEU2) antibody
  • neuraminidase 2 (Neu2) antibody
  • sialidase 2 (Neu2) antibody
  • MBS antibody
  • MSS antibody
  • MTS antibody
  • NEU2 antibody
  • SIAL2 antibody

Protein level used designations for NEU2

sialidase 2 (cytosolic sialidase) , sialidase-2-like , N-acetyl-alpha-neuraminidase 2 , brain sialidase , cystolic sialidase , cytosolic sialidase , murine thymic sialidase , sialidase-2 , skeletal muscle sialidase , neuraminidase 2

GENE ID SPECIES
486166 Canis lupus familiaris
713979 Macaca mulatta
768823 Gallus gallus
100404163 Callithrix jacchus
100598166 Nomascus leucogenys
23956 Mus musculus
29204 Rattus norvegicus
4759 Homo sapiens
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