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High-affinity self-ligand important in bidirectional T- cell to B-cell stimulation. Additionally we are shipping SLAMF1 Antibodies (279) and SLAMF1 Proteins (20) and many more products for this protein.
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We demonstrated that Bacille Calmette-Guerin infection significantly upregulated SLAMF1, which enhanced inflammatory response by activating the NF-kappaB (show NFKB1 ELISA Kits) signaling pathway and facilitated bacterial clearance in BCG (show SLC11A1 ELISA Kits)-infected RAW264.7 cells and mice.
Slamf1 and Slamf8 (show SLAMF8 ELISA Kits) govern ROS (show ROS1 ELISA Kits)-dependent innate immune responses of myeloid cells.
The combined effects of RIIB deletion and pathogenic SLAM can lead to severe lupus nephritis in the B6 genetic background.
SLAM-SAP (show APCS ELISA Kits) signaling promotes differentiation of IL-17 (show IL17A ELISA Kits)-producing T cells and progression of experimental autoimmune encephalomyelitis.
The goal of the current study was to determine whether Slam haplotype affected NKT (show CTSL1 ELISA Kits) and Vgamma4+ T-cell responses subsequent to coxsackievirus b3 infection.
Signaling lymphocyte activation molecule regulates development of colitis in mice.
Slamf1, which controls phagosomal/lysosomal fusion and phagosomal NADPH-oxidase (show NOX1 ELISA Kits) activity, is required for T.cruzi replication in macrophages and dendritic cells, but not in other cells, which do not express the receptor.
conclude that Slamf1 recruits a subset of Vps34 (show PIK3C3 ELISA Kits)-associated proteins, which is involved in membrane fusion and NOX2 (show CYBB ELISA Kits) regulation
Slamf1 is a bacterial sensor that regulates intracellular enzyme activities involved in the removal of Gram-negative bacteria.
SLAM signaling drives most of (interleukin) IL-4 (show IL4 ELISA Kits) production by germinal center T follicular helper CD4 (show CD4 ELISA Kits) cells.
Malignant B-cell lines at the different stages of maturation only partially resemble their normal counterparts by CD150 expression. In malignant B-cell lines, CD150 expression on mRNA level is much broader than on protein level. CD150 isoforms are differentially expressed in normal and malignant B cells with predominant expression of mCD150 isoform.
Data suggest that SLAMF1 is another significant piece in the intricate defective immune-regulatory function of patients with SLE.
results indicate that loss of SLAMF1 expression in chronic lymphocytic leukemia modulates genetic pathways
Upstream open reading frames regulate translation of the long isoform of SLAMF1 mRNA that encodes costimulatory receptor CD150
Molecular dynamics analysis revealed that mutant R32Q and T53I structures of SAP (show APCS ELISA Kits) exhibited structural variation with respect to their backbone atoms before and after binding with the unphosphorylated SLAM peptide.
Signaling lymphocytic activation molecule (SLAM)/SLAM-associated protein pathway regulates human B-cell tolerance.
Latent membrane protein 1 was responsible for the CD150 upregulation.
Experimental adaptation of wild-type canine distemper virus (CDV) to the human entry receptor CD150
Two genes were consistently retained in the models with clinical variables: SKI (show SKI ELISA Kits) (v-SKI (show SKI ELISA Kits) avian sarcoma viral oncogene (show RAB1A ELISA Kits) homolog) and SLAMF1 (signaling lymphocytic activation molecule family member 1; CD150).
High-affinity self-ligand important in bidirectional T- cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates.
signaling lymphocyte activation molecule
, signaling lymphocytic activation molecule
, signaling lymphocytic activation molecule family member 1