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The ADF (actin-depolymerizing factor)/cofilin family (see MIM 601442) is composed of stimulus-responsive mediators of actin dynamics. Additionally we are shipping SSH3 Proteins (5) and SSH3 Kits (2) and many more products for this protein.
Showing 10 out of 54 products:
Human Polyclonal SSH3 Primary Antibody for EIA, FACS - ABIN954955
Kousaka, Kiyonari, Oshima, Nagafuchi, Shima, Chisaka, Uemura: Slingshot-3 dephosphorylates ADF/cofilin but is dispensable for mouse development. in Genesis (New York, N.Y. : 2000) 2008
Show all 4 references for ABIN954955
Human Polyclonal SSH3 Primary Antibody for FACS, IF - ABIN655643
Kligys, Claiborne, DeBiase, Hopkinson, Wu, Mizuno, Jones: The slingshot family of phosphatases mediates Rac1 regulation of cofilin phosphorylation, laminin-332 organization, and motility behavior of keratinocytes. in The Journal of biological chemistry 2007
Show all 2 references for ABIN655643
Human Polyclonal SSH3 Primary Antibody for IHC, ELISA - ABIN1451472
Niwa, Nagata-Ohashi, Takeichi, Mizuno, Uemura: Control of actin reorganization by Slingshot, a family of phosphatases that dephosphorylate ADF/cofilin. in Cell 2002
Human Polyclonal SSH3 Primary Antibody for IHC (p), IP - ABIN253146
Lu, Boora, Seabra, Rabai, Fenton, Reiman, Nagy, Maher: Knockdown of Slingshot 2 (SSH2) serine phosphatase induces Caspase3 activation in human carcinoma cell lines with the loss of the Birt-Hogg-Dubé tumour suppressor gene (FLCN). in Oncogene 2014
Dephosphorylates actin-depolymerizing factor/cofilin (show CFL1 Antibodies), but is not essential for viability, fertility, or development of epithelial tissues.
Expression of phosphatase-dead versions of SSH proteins, SSH1 (show SSH1 Antibodies), SSH2 (show SSH2 Antibodies) & SSH3 results in phosphorylation/inactivation of cofilin (show CFL1 Antibodies), changes in cytoskeleton organization, loss of cell polarity, and assembly of aberrant arrays of laminin-332 in keratinocytes.
The ADF (actin-depolymerizing factor)/cofilin family (see MIM 601442) is composed of stimulus-responsive mediators of actin dynamics. ADF/cofilin proteins are inactivated by kinases such as LIM domain kinase-1 (LIMK1\; MIM 601329). The SSH family appears to play a role in actin dynamics by reactivating ADF/cofilin proteins in vivo (Niwa et al., 2002
slingshot homolog 3 (Drosophila)
, protein phosphatase Slingshot homolog 3
, protein phosphatase Slingshot homolog 3-like
, SSH-like protein 3
, slingshot-like 3
, slingshot 3
, slingshot homolog 3