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Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 3 Proteins (SLC1A3)

SLC1A3 encodes a member of a member of a high affinity glutamate transporter family. Additionally we are shipping Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 3 Antibodies (91) and Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 3 Kits (11) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SLC1A3 29483 P24942
SLC1A3 6507 P43003
SLC1A3 20512 P56564
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Top Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 3 Proteins at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
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Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
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HOST_Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
$246.96
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HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
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HOST_Escherichia coli (E. coli) Human Un-conjugated   5 applications Log in to see 1 to 2 Days
$312.71
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SLC1A3 Proteins by Origin and Source

Origin Expressed in Conjugate
Rat (Rattus)
Human , ,
,
Mouse (Murine) ,

More Proteins for Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 3 (SLC1A3) Interaction Partners

Fruit Fly (Drosophila melanogaster) Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 3 (SLC1A3) interaction partners

  1. Eaat1 expression is promoted by Fringe-mediated neuron-glial communication during development and suggest that Eaat1 plays an essential role in regulating central nervous system neural circuits that control locomotion in Drosophila

  2. dEAAT1 is present at the adult, but surprisingly not at embryonic and larval NMJ, suggesting a physiological maturation of the junction during metamorphosis

Human Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 3 (SLC1A3) interaction partners

  1. SPAK (show STK39 Proteins) and OSR1 (show OXSR1 Proteins) are powerful negative regulators of the excitatory glutamate (show GRIN1 Proteins) transporters EAAT1 and EAAT2 (show SLC1A2 Proteins).

  2. There was no association between pyramidal cell EAAT1 splice variant expression and schizophrenia.

  3. data provide additional insights into the mechanism by which substrates gate the anion conductance in EAATs and suggest that in EAAT1, Arg-388 is a critical element for the structural coupling between the substrate translocation and the gating mechanisms

  4. discovering compounds that can enhance EAAT1 expression and activity may be a novel strategy for therapeutic treatment of glaucoma.

  5. Results showed that EAAT2 (show SLC1A2 Proteins) levels were significantly decreased in the essential tremor cerebellar cortex, in contrast to similar levels of EAAT1 levels between essential tremor cases and controls

  6. EAAT1 polymorphism which is involved in the Regulation of extracellular glutamate (show GRIN1 Proteins) concentrations, influences Cognitive performances with a detrimental effect of T/T homozygosis.

  7. the delivered miR (show MLXIP Proteins)-124 increased the expression of the glutamate (show GRIN1 Proteins) transporters, EAAT1 in NPCs and EAAT2 (show SLC1A2 Proteins) in both NPCs and astrocytes.

  8. Results describe EAAT1 and EAAT2 (show SLC1A2 Proteins) labeling in the prefrontal cortex in human postmortem control brains at the light and electron microscopic level

  9. Its dysregulation may contribute to the pathology and possibly affect the onset of fragile X (show FMR1 Proteins)-associated tremor/ataxia (show USP14 Proteins) syndrome.

  10. Increased SLC1A3 expression in the cerebellum of elderly schizophrenia patients indicates facilitated transport and may result in reduced glutamate (show GRIN1 Proteins) neurotransmission.

Mouse (Murine) Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 3 (SLC1A3) interaction partners

  1. glutamate/aspartate transporter (GLAST) was elevated in 8- to 10- and/or 20- to 22-month GHR (show GHR Proteins)-KO mice when comparing genotypes

  2. This study findings demonstrate that Ascl1 (show ASCL1 Proteins)(CreERT2) and Glast(CreERT2) mouse lines enable simple and reliable labeling of adult-born GC lineages within restricted time windows.

  3. arundic acid treatment prevented RGC death by upregulating GLAST in heterozygous (GLAST(+/-)) mice

  4. Results show that expression of GLAST is decreased in cerebellar astrocytes in a mouse model of SCA1; decrease occurs in non-cell autonomous manner late in disease and correlates well with the loss of Purkinje neurons

  5. we have demonstrated for the first time that DOR receptor activation induces astrocytic expression of EAAT1 and EAAT2 (show SLC1A2 Proteins)

  6. The result showed significant correlation between changes in GLUT 8 (show SLC2A8 Proteins) and glucose levels with changes in StAR level in the testis and circulating testosterone level in the mice from birth to senescence

  7. EAAT1 activity and sodium potassium-ATPase activity are co-regulated by a tightly coupled homeostatic relationship in astrocytes.

  8. Study suggests that there is a remarkable subcellular heterogeneity of GLAST and GLT-1 expression in the developing hippocampus

  9. TNR (show TNR Proteins) is expressed in a subset of astrocytes and contributes to glutamate (show GRIN1 Proteins) homeostasis by regulating astrocytic GLAST expression.

  10. Results suggest that an impairment of astrocytic ascorbate-release may exacerbate neuronal dysfunction in neurodegenerative disorders and acute brain injury in which excitotoxicity and/or GLAST deregulation have been implicated.

Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 3 (SLC1A3) Protein Profile

Protein Summary

This gene encodes a member of a member of a high affinity glutamate transporter family. Mutations in this gene are associated with episodic ataxia, Type 6. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with SLC1A3

  • Excitatory amino acid transporter 1 (Eaat1)
  • excitatory amino acid transporter 1 (EAAT1)
  • excitatory amino acid transporter 1 (PTRG_00379)
  • excitatory amino acid transporter 1 (Tsp_02392)
  • solute carrier family 1 (glial high affinity glutamate transporter), member 3a (slc1a3a)
  • solute carrier family 1 (glial high affinity glutamate transporter), member 3 (SLC1A3)
  • solute carrier family 1 (glial high affinity glutamate transporter), member 3 (Slc1a3)
  • AF001784 protein
  • AI504299 protein
  • B430115D02Rik protein
  • CG3747 protein
  • dEAAT protein
  • dEaat1 protein
  • Dglt-1 protein
  • Dglut-1 protein
  • Dmel\\CG3747 protein
  • EA6 protein
  • EAAT protein
  • Eaat1 protein
  • GLAST protein
  • GLAST-1 protein
  • GLAST1 protein
  • GLU-T protein
  • GluT-1 protein
  • Gmt1 protein
  • MGluT1 protein
  • SLC1A3 protein
  • wu:fb98e05 protein
  • wu:fd50b05 protein
  • zgc:56661 protein
  • zgc:77768 protein

Protein level used designations for SLC1A3

CG3747-PA , CG3747-PB , CG3747-PC , CG3747-PD , Eaat1-PA , Eaat1-PB , Eaat1-PC , Eaat1-PD , drosophila glutamate transporter-1 , excitatory amino acid transporter 1 , glutamate transporter , sodium-dependent excitatory amino acid transporter 1 , sodium-dependent glutamate transporter , sodium-excitatory-glutamate-cotransporter , EAAT1A , excitatory amino acid transporter SLC1A3a , glasta , solute carrier family 1 (glial high affinity glutamate transporter), member 3 , Na+-dependent glutamate/aspartate transporter , Sodium-dependent glutamate/aspartate transporter 1 , excitatory amino acid transporter 1-like , GLAST-1 , glial glutamate transporter , glutamate/aspartate transporter , sodium-dependent glutamate/aspartate transporter 1 , solute carrier family 1, member 3 , solute carrier family 1 member 3 , glial high affinity glutamate transporter , high-affinity neuronal glutamate transporter

GENE ID SPECIES
34251 Drosophila melanogaster
443246 Ovis aries
6340496 Pyrenophora tritici-repentis Pt-1C-BFP
10908153 Trichinella spiralis
323439 Danio rerio
395443 Gallus gallus
461918 Pan troglodytes
701109 Macaca mulatta
100014533 Monodelphis domestica
100408230 Callithrix jacchus
100433620 Pongo abelii
100479747 Ailuropoda melanoleuca
100587553 Nomascus leucogenys
29483 Rattus norvegicus
6507 Homo sapiens
20512 Mus musculus
282354 Bos taurus
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